Supernatural T cells: genetic modification of T cells for cancer therapy (Q36328805)

13 August 2017

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title

Supernatural T cells: genetic modification of T cells for cancer therapy (English)

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13 August 2017

Michael H Kershaw

1

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Phillip K. Darcy

object named as

Phillip K Darcy

series ordinal

4

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Mark J. Smyth

object named as

Mark J Smyth

series ordinal

3

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Michele W.L. Teng

series ordinal

2

object named as

Michele W L Teng

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13 August 2017

publication date

1 December 2005

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Nature Reviews Immunology

13 August 2017

published in

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13 August 2017

volume

5

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13 August 2017

issue

12

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13 August 2017

page(s)

928-940

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A fresh look at tumor immunosurveillance and immunotherapy.

13 August 2017

cites work

1 reference

Relationship of causative factors in spontaneous regression of cancer to immunologic factors possibly effective in cancer

21 January 2018

1 reference

Progress in human tumour immunology and immunotherapy

21 January 2018

1 reference

Rituximab: ongoing and future clinical development

21 January 2018

1 reference

Long-term restoration of immunity against Epstein-Barr virus infection by adoptive transfer of gene-modified virus-specific T lymphocytes

21 January 2018

1 reference

Cancer immunotherapy: moving beyond current vaccines

21 January 2018

1 reference

Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

21 January 2018

1 reference

Natural selection of tumor variants in the generation of "tumor escape" phenotypes

21 January 2018

1 reference

The immunobiology of cancer immunosurveillance and immunoediting

21 January 2018

1 reference

Primary human lymphocytes transduced with NY-ESO-1 antigen-specific TCR genes recognize and kill diverse human tumor cell lines

21 January 2018

1 reference

Circumventing tolerance to a human MDM2-derived tumor antigen by TCR gene transfer

21 January 2018

1 reference

Grafting primary human T lymphocytes with cancer-specific chimeric single chain and two chain TCR.

21 January 2018

1 reference

Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity

21 January 2018

1 reference

Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors

21 January 2018

1 reference

Lysis of ovarian cancer cells by human lymphocytes redirected with a chimeric gene composed of an antibody variable region and the Fc receptor gamma chain

21 January 2018

1 reference

Eradication of systemic B-cell tumors by genetically targeted human T lymphocytes co-stimulated by CD80 and interleukin-15.

21 January 2018

1 reference

Epstein-Barr virus-specific human T lymphocytes expressing antitumor chimeric T-cell receptors: potential for improved immunotherapy

21 January 2018

1 reference

Antigen-dependent CD28 signaling selectively enhances survival and proliferation in genetically modified activated human primary T lymphocytes

21 January 2018

1 reference

A recombinant antibody with the antigen-specific, major histocompatibility complex-restricted specificity of T cells.

21 January 2018

1 reference

A chimeric receptor that selectively targets membrane-bound carcinoembryonic antigen (mCEA) in the presence of soluble CEA.

21 January 2018

1 reference

T-cell killing of heterogenous tumor or viral targets with bispecific chimeric immune receptors

21 January 2018

1 reference

Melanocyte destruction after antigen-specific immunotherapy of melanoma: direct evidence of t cell-mediated vitiligo.

21 January 2018

1 reference

Vaccination with a recombinant vaccinia virus encoding a "self" antigen induces autoimmune vitiligo and tumor cell destruction in mice: requirement for CD4(+) T lymphocytes.

21 January 2018

1 reference

Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

21 January 2018

1 reference

Reversal in the immunodominance hierarchy in secondary CD8+ T cell responses to influenza A virus: roles for cross-presentation and lysis-independent immunodomination

21 January 2018

1 reference

Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients

21 January 2018

1 reference

Redirecting mouse CTL against colon carcinoma: superior signaling efficacy of single-chain variable domain chimeras containing TCR-zeta vs Fc epsilon RI-gamma

21 January 2018

1 reference

Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRζ /CD28 receptor

21 January 2018

1 reference

Single-chain antigen recognition receptors that costimulate potent rejection of established experimental tumors

21 January 2018

1 reference

Activation of resting human primary T cells with chimeric receptors: costimulation from CD28, inducible costimulator, CD134, and CD137 in series with signals from the TCR zeta chain

21 January 2018

1 reference

Chimeric receptors with 4-1BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia.

21 January 2018

1 reference

Integrated src kinase and costimulatory activity enhances signal transduction through single-chain chimeric receptors in T lymphocytes.

21 January 2018

1 reference

Role of T cell costimulation in anti-viral immunity

21 January 2018

1 reference

Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells

21 January 2018

1 reference

The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

21 January 2018

1 reference

A novel transcription factor, T-bet, directs Th1 lineage commitment

21 January 2018

1 reference

Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis.

21 January 2018

1 reference

Specific T Helper Cell Requirement for Optimal Induction of Cytotoxic T Lymphocytes against Major Histocompatibility Complex Class II Negative Tumors

21 January 2018

1 reference

Immunotherapy of cytotoxic T cell-resistant tumors by T helper 2 cells: an eotaxin and STAT6-dependent process.

21 January 2018

1 reference

Recognition of human colon cancer by T cells transduced with a chimeric receptor gene

21 January 2018

1 reference

Targeting of G(D2)-positive tumor cells by human T lymphocytes engineered to express chimeric T-cell receptor genes

21 January 2018

1 reference

Massive Expansion of Antigen-Specific CD8+ T Cells during an Acute Virus Infection

21 January 2018

1 reference

Reprogramming of virus-specific T cells into leukemia-reactive T cells using T cell receptor gene transfer

21 January 2018

1 reference

Dual-specific T cells combine proliferation and antitumor activity

21 January 2018

1 reference

Generation of functional antigen-specific T cells in defined genetic backgrounds by retrovirus-mediated expression of TCR cDNAs in hematopoietic precursor cells

21 January 2018

1 reference

Enhanced antilymphoma efficacy of CD19-redirected influenza MP1-specific CTLs by cotransfer of T cells modified to present influenza MP1.

21 January 2018

1 reference

The ABCs of artificial antigen presentation

21 January 2018

1 reference

Transduction of an IL-2 gene into human melanoma-reactive lymphocytes results in their continued growth in the absence of exogenous IL-2 and maintenance of specific antitumor activity

21 January 2018

1 reference

Enhanced signaling through the IL-2 receptor in CD8+ T cells regulated by antigen recognition results in preferential proliferation and expansion of responding CD8+ T cells rather than promotion of cell death

21 January 2018

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Restoration of CD28 expression in CD28- CD8+ memory effector T cells reconstitutes antigen-induced IL-2 production

21 January 2018

1 reference

Immortalization of human CD8+ T cell clones by ectopic expression of telomerase reverse transcriptase

21 January 2018

1 reference

Selective modification of antigen-specific CD4(+) T cells by retroviral-mediated gene transfer and in vitro sensitization with dendritic cells

21 January 2018

1 reference

Bcl-2 overexpression enhances tumor-specific T-cell survival

21 January 2018

1 reference

Retroviral transduction of human peripheral blood lymphocytes with Bcl-X(L) promotes in vitro lymphocyte survival in pro-apoptotic conditions

21 January 2018

1 reference

Human cytotoxic T lymphocytes with reduced sensitivity to Fas-induced apoptosis.

21 January 2018

1 reference

Enhancement of antitumor immunity by CTLA-4 blockade

21 January 2018

1 reference

Chemokines: agents for the immunotherapy of cancer?

21 January 2018

1 reference

Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(+)CD25(+) regulatory T cells

21 January 2018

1 reference

Adapting a transforming growth factor beta-related tumor protection strategy to enhance antitumor immunity.

21 January 2018

1 reference

A strategy for treatment of Epstein-Barr virus-positive Hodgkin's disease by targeting interleukin 12 to the tumor environment using tumor antigen-specific T cells

21 January 2018

1 reference

A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

21 January 2018

1 reference

HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia

21 January 2018

1 reference

An inducible caspase 9 safety switch for T-cell therapy

21 January 2018

1 reference

A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease

21 January 2018

1 reference

Liver-directed gene therapy: quantitative evaluation of promoter elements by using in vivo retroviral transduction

21 January 2018

1 reference

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

21 January 2018

1 reference

Self Antigens Expressed by Solid Tumors Do Not Efficiently Stimulate Naive or Activated T Cells: Implications for Immunotherapy

21 January 2018

1 reference

Transforming growth factor-beta in T-cell biology

21 January 2018

1 reference

Interleukin-10: a cytokine used by tumors to escape immunosurveillance

21 January 2018

1 reference

Correlation between tumor regression and T cell responses in melanoma patients vaccinated with a MAGE antigen

21 January 2018

1 reference

Immunization with Melan-A peptide-pulsed peripheral blood mononuclear cells plus recombinant human interleukin-12 induces clinical activity and T-cell responses in advanced melanoma

21 January 2018

1 reference

Phase I trial of intravenous peptide-pulsed dendritic cells in patients with metastatic melanoma

21 January 2018

1 reference

Phase 2 trial of vaccination with tyrosinase peptides and granulocyte-macrophage colony-stimulating factor in patients with metastatic melanoma.

21 January 2018

1 reference

Clinical and immunologic results of a randomized phase II trial of vaccination using four melanoma peptides either administered in granulocyte-macrophage colony-stimulating factor in adjuvant or pulsed on dendritic cells

21 January 2018

1 reference

A phase I trial of cytotoxic T-lymphocyte precursor-oriented peptide vaccines for colorectal carcinoma patients

21 January 2018

1 reference

Combining a recombinant cancer vaccine with standard definitive radiotherapy in patients with localized prostate cancer

21 January 2018

1 reference

Vaccination of cancer patients against telomerase induces functional antitumor CD8+ T lymphocytes

21 January 2018

1 reference

Induction of primary NY-ESO-1 immunity: CD8+ T lymphocyte and antibody responses in peptide-vaccinated patients with NY-ESO-1+ cancers.

21 January 2018

1 reference

Phase I study of a vaccine using recombinant vaccinia virus expressing PSA (rV-PSA) in patients with metastatic androgen-independent prostate cancer

21 January 2018

1 reference

Vaccination with p53-peptide-pulsed dendritic cells, of patients with advanced breast cancer: report from a phase I study

21 January 2018

1 reference

A multivalent bcr-abl fusion peptide vaccination trial in patients with chronic myeloid leukemia

21 January 2018

1 reference

Rejection of Syngeneic Colon Carcinoma by CTLs Expressing Single-Chain Antibody Receptors Codelivering CD28 Costimulation

21 January 2018

1 reference

Immunotherapy of cancer using systemically delivered gene-modified human T lymphocytes

21 January 2018

1 reference

Generation of gene-modified T cells reactive against the angiogenic kinase insert domain-containing receptor (KDR) found on tumor vasculature

21 January 2018

1 reference

Specific targeting of EGP-2+ tumor cells by primary lymphocytes modified with chimeric T cell receptors

21 January 2018

1 reference

Targeting of T lymphocytes to melanoma cells through chimeric anti-GD3 immunoglobulin T-cell receptors

21 January 2018

1 reference

Protocol for gene transduction and expansion of human T lymphocytes for clinical immunogene therapy of cancer

21 January 2018

1 reference

Spontaneous regression of hepatic metastases from gastric carcinoma

21 January 2018

1 reference

Reconstitution of Cellular Immunity against Cytomegalovirus in Recipients of Allogeneic Bone Marrow by Transfer of T-Cell Clones from the Donor

31 March 2020

1 reference

Immunotherapy through TCR gene transfer

31 March 2020

1 reference

Cooperation of Human Tumor-Reactive CD4+ and CD8+ T Cells after Redirection of Their Specificity by a High-Affinity p53A2.1-Specific TCR

31 March 2020

1 reference

Tumor-specific T cell activation by recombinant immunoreceptors: CD3 zeta signaling and CD28 costimulation are simultaneously required for efficient IL-2 secretion and can be integrated into one combined CD28/CD3 zeta signaling receptor molecule

31 March 2020

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Differential expression and costimulatory effect of 4-1BB (CD137) and CD28 molecules on cytokine-induced murine CD8(+) Tc1 and Tc2 cells

31 March 2020

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Anti-tumor activity of human T cells expressing the CC49-zeta chimeric immune receptor

31 March 2020

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Kinetics of TCR use in response to repeated epitope-specific immunization

31 March 2020

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Redirecting migration of T cells to chemokine secreted from tumors by genetic modification with CXCR2

31 March 2020

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Murine leukemia induced by retroviral gene marking

31 March 2020

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Safety of retroviral gene marking with a truncated NGF receptor

31 March 2020

1 reference

Infusion of dendritic cells pulsed with HLA-A2-specific prostate-specific membrane antigen peptides: a phase II prostate cancer vaccine trial involving patients with hormone-refractory metastatic disease

31 March 2020

1 reference

A phase I vaccine trial with peptides reflecting ras oncogene mutations of solid tumors.

31 March 2020

1 reference

Phase I/II study of treatment with dendritic cell vaccines in patients with disseminated melanoma

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRI1729

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Dimensions Publication ID

13 August 2017

1048553908

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