Genetic variation in G-protein-coupled receptors--consequences for G-protein-coupled receptors as drug targets (Q36318560)

13 August 2017

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title

Genetic variation in G-protein-coupled receptors--consequences for G-protein-coupled receptors as drug targets (English)

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G protein-coupled receptor

13 August 2017

main subject

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Chih-Min Tang

1

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13 August 2017

Paul A Insel

series ordinal

2

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13 August 2017

language of work or name

English

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publication date

1 December 2005

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Expert Opinion on Therapeutic Targets

13 August 2017

published in

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13 August 2017

volume

9

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13 August 2017

issue

6

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13 August 2017

page(s)

1247-1265

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The Sequence of the Human Genome

13 August 2017

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Polymorphisms of cardiac presynaptic alpha2C adrenergic receptors: Diverse intragenic variability with haplotype-specific functional effects

21 January 2018

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Synergistic polymorphisms of beta1- and alpha2C-adrenergic receptors and the risk of congestive heart failure

21 January 2018

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A functional polymorphism in the promoter region of the dopamine D2 receptor gene is associated with schizophrenia

21 January 2018

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-141 C del/ins polymorphism of the dopamine receptor 2 gene is associated with schizophrenia in a British population

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A genetic polymorphism in the promoter region of DRD4 associated with expression and schizophrenia

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Elevation of D4 dopamine receptor mRNA in postmortem schizophrenic brain

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Polymorphisms of the 5' leader cistron of the human beta2-adrenergic receptor regulate receptor expression

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A cluster of single nucleotide polymorphisms in the 5'-leader of the human dopamine D3 receptor gene (DRD3) and its relationship to schizophrenia.

21 January 2018

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Complex promoter and coding region beta 2-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness

21 January 2018

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Association of angiotensin II type 1 receptor polymorphism with resistant essential hypertension

21 January 2018

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Identification of a naturally occurring 21 bp deletion in alpha 2c noradrenergic receptor gene and cognitive correlates to antipsychotic treatment

21 January 2018

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The calcium sensing receptor and its alternatively spliced form in keratinocyte differentiation

21 January 2018

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5-HT4 receptors: gene, transduction and effects on olfactory memory.

21 January 2018

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Regulation of serotonin 2C receptor pre-mRNA editing by serotonin

21 January 2018

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Regulation of serotonin-2C receptor G-protein coupling by RNA editing

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RNA editing of the human serotonin 5-hydroxytryptamine 2C receptor silences constitutive activity

21 January 2018

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RNA editing of the human serotonin 5-HT2C receptor disrupts transactivation of the small G-protein RhoA.

21 January 2018

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The regulatory mechanisms of export trafficking of G protein-coupled receptors.

21 January 2018

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Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction

21 January 2018

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The molecular basis of nephrogenic diabetes insipidus

21 January 2018

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21 January 2018

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beta2 adrenoceptor gene polymorphisms in cystic fibrosis lung disease

21 January 2018

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Beta2-adrenoceptor gene polymorphisms

21 January 2018

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Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial

21 January 2018

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Efficacy as a vector: the relative prevalence and paucity of inverse agonism

21 January 2018

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Modification of human 5-HT(2C) receptor function by Cys23Ser, an abundant, naturally occurring amino-acid substitution.

21 January 2018

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A missense mutation of the endothelin-B receptor gene in multigenic Hirschsprung's disease

21 January 2018

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Transduction of receptor signals by beta-arrestins

21 January 2018

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Characterization of a common susceptibility locus for asthma-related traits

21 January 2018

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Haplotypes of G protein-coupled receptor 154 are associated with childhood allergy and asthma

21 January 2018

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Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.

21 January 2018

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21 January 2018

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GPR40 gene Arg211His polymorphism may contribute to the variation of insulin secretory capacity in Japanese men

21 January 2018

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Sex-specific association between bipolar affective disorder in women and GPR50, an X-linked orphan G protein-coupled receptor

21 January 2018

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Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54

21 January 2018

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The GPR54 gene as a regulator of puberty

21 January 2018

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Two novel missense mutations in g protein-coupled receptor 54 in a patient with hypogonadotropic hypogonadism.

21 January 2018

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Are beta2-adrenoceptor polymorphisms important in asthma--an unravelling story

21 January 2018

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Pharmacogenetics and response to beta-adrenergic receptor antagonists in heart failure

21 January 2018

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Molecular basis of ethnic differences in drug disposition and response

21 January 2018

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21 January 2018

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GPCR expression in the heart; "new" receptors in myocytes and fibroblasts

21 January 2018

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5-HT2A and 5-HT2C receptor polymorphisms and psychopathology in late onset Alzheimer's disease.

21 January 2018

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An asn to lys polymorphism in the third intracellular loop of the human alpha 2A-adrenergic receptor imparts enhanced agonist-promoted Gi coupling

21 January 2018

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A four amino acid deletion polymorphism in the third intracellular loop of the human alpha 2C-adrenergic receptor confers impaired coupling to multiple effectors

21 January 2018

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Amino acid 49 polymorphisms of the human beta1-adrenergic receptor affect agonist-promoted trafficking

21 January 2018

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A gain-of-function polymorphism in a G-protein coupling domain of the human beta1-adrenergic receptor

21 January 2018

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Association between genetic polymorphisms of the beta2-adrenoceptor and response to albuterol in children with and without a history of wheezing

21 January 2018

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Polymorphic variants of the beta2-adrenergic receptor (ADRB2) gene and ADRB2-related propanolol-induced dyslipidemia in the Colombian population

21 January 2018

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21 January 2018

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21 January 2018

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CCR5 promoter alleles and specific DNA binding factors

21 January 2018

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Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

21 January 2018

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Sequence variants of the gene encoding chemoattractant receptor expressed on Th2 cells (CRTH2) are associated with asthma and differentially influence mRNA stability

21 January 2018

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Functional analysis of the human D2 dopamine receptor missense variants

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Follicle-stimulating hormone receptor polymorphisms in a population of infertile women

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Impaired receptor binding and activation associated with a human prostacyclin receptor polymorphism

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Sequence variation in the promoter region of the cholinergic receptor muscarinic 3 gene and asthma and atopy

21 January 2018

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Single nucleotide polymorphisms in the human mu opioid receptor gene alter basal G protein coupling and calmodulin binding

21 January 2018

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A polymorphic protease-activated receptor 2 (PAR2) displaying reduced sensitivity to trypsin and differential responses to PAR agonists

21 January 2018

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Human P2Y2 receptor polymorphism: identification and pharmacological characterization of two allelic variants

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Identification of the platelet ADP receptor targeted by antithrombotic drugs

21 January 2018

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Rhodopsin mutations in autosomal dominant retinitis pigmentosa

21 January 2018

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Evaluation of the G protein coupled receptor-75 (GPR75) in age related macular degeneration

21 January 2018

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Association of the C(-1019)G 5-HT1A functional promoter polymorphism with antidepressant response

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Molecular Analysis and Genetic Mapping of the Rhodopsin Gene in Families with Autosomal Dominant Retinitis Pigmentosa

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10.1517/14728222.9.6.1247

21 January 2018

Identifiers

DOI

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13 August 2017

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