Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2. (Q36258971)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9689088%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

title

Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2 (English)

1 reference

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13 November 2019

2

1 reference

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13 November 2019

author name string

M Weinstein

1

1 reference

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13 November 2019

C Li

3

1 reference

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13 November 2019

X Xu

4

1 reference

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13 November 2019

J Gotay

5

1 reference

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13 November 2019

C X Deng

6

1 reference

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13 November 2019

language of work or name

English

0 references

publication date

1 August 1998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9689088%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

13 November 2019

published in

1 reference

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13 November 2019

volume

95

1 reference

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13 November 2019

issue

16

1 reference

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13 November 2019

page(s)

9378-9383

1 reference

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Smad2 Signaling in Extraembryonic Tissues Determines Anterior-Posterior Polarity of the Early Mouse Embryo

13 November 2019

cites work

1 reference

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The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice

30 September 2017

1 reference

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The type I activin receptor ActRIB is required for egg cylinder organization and gastrulation in the mouse

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

TGF-β signalling from cell membrane to nucleus through SMAD proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

Smad8 mediates the signaling of the ALK-2 [corrected] receptor serine kinase

30 September 2017

1 reference

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Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

30 September 2017

1 reference

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30 September 2017

1 reference

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A structural basis for mutational inactivation of the tumour suppressor Smad4

30 September 2017

1 reference

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Cloning and characterization of a novel member of the human Mad gene family (MADH6)

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

Identification of Smad2, a human Mad-related protein in the transforming growth factor beta signaling pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

TGFbeta signaling: receptors, transducers, and Mad proteins.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

A human Mad protein acting as a BMP-regulated transcriptional activator

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

Fibroblast growth factor receptor 3 is a negative regulator of bone growth

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

Embryonic expression of Lim-1, the mouse homolog of Xenopus Xlim-1, suggests a role in lateral mesoderm differentiation and neurogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

Fgf-8 expression in the post-gastrulation mouse suggests roles in the development of the face, limbs and central nervous system.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

TGF beta signals through a heteromeric protein kinase receptor complex

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

Drosophila Dpp signaling is mediated by the punt gene product: A dual ligand-binding type II receptor of the TGFβ receptor family

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

From receptor to nucleus: the Smad pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

The murine H19 gene is activated during embryonic stem cell differentiation in vitro and at the time of implantation in the developing embryo

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

Smad6 inhibits signalling by the TGF-β superfamily

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

Insertional mutation of a gene involved in growth regulation of the early mouse embryo

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21346

Murine FGFR-1 is required for early postimplantation growth and axial organization

22 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9689088

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9689088

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.95.16.9378

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9689088%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

0 references

release_cyar7ilmsvb4jakyecwweocq2u

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/cyar7ilmsvb4jakyecwweocq2u

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9689088%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

PubMed publication ID

9689088

1 reference