Protective spin-labeled fluorenes maintain amyloid beta peptide in small oligomers and limit transitions in secondary structure (Q36244824)

13 August 2017

Protective spin-labeled fluorenes maintain amyloid beta peptide in small oligomers and limit transitions in secondary structure (English)

1 reference

13 August 2017

10

1 reference

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2 June 2020

author name string

Robin Altman

1

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2 June 2020

Sonny Ly

2

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2 June 2020

Silvia Hilt

3

1 reference

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2 June 2020

Jitka Petrlova

4

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2 June 2020

Izumi Maezawa

5

1 reference

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2 June 2020

Tamás Kálai

6

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2 June 2020

Kálmán Hideg

7

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2 June 2020

Lee-Way Jin

8

1 reference

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2 June 2020

Ted A Laurence

9

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2 June 2020

language of work or name

English

0 references

publication date

13 September 2015

1 reference

Biochimica et Biophysica Acta

13 August 2017

1 reference

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2 June 2020

volume

1854

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2 June 2020

issue

12

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2 June 2020

page(s)

1860-1870

1 reference

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Accurate secondary structure prediction and fold recognition for circular dichroism spectroscopy

2 June 2020

cites work

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The influence of spin-labeled fluorene compounds on the assembly and toxicity of the aβ peptide

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Specific soluble oligomers of amyloid-β peptide undergo replication and form non-fibrillar aggregates in interfacial environments

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Intrinsic disorder modulates protein self-assembly and aggregation

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Unraveling the early events of amyloid-β protein (Aβ) aggregation: techniques for the determination of Aβ aggregate size

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Synthesis and study of 2-amino-7-bromofluorenes modified with nitroxides and their precursors as dual anti-amyloid and antioxidant active compounds.

1 October 2017

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A differential association of Apolipoprotein E isoforms with the amyloid-β oligomer in solution.

1 October 2017

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Tetracycline prevents Aβ oligomer toxicity through an atypical supramolecular interaction.

1 October 2017

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Size-dependent neurotoxicity of beta-amyloid oligomers.

1 October 2017

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Fibrillar oligomers nucleate the oligomerization of monomeric amyloid beta but do not seed fibril formation

1 October 2017

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Restored degradation of the Alzheimer's amyloid-beta peptide by targeting amyloid formation

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

1 October 2017

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The structural basis of protein folding and its links with human disease

1 October 2017

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Designing conditions for in vitro formation of amyloid protofilaments and fibrils

1 October 2017

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1 October 2017

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1 October 2017

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Nature of the amyloid-beta monomer and the monomer-oligomer equilibrium.

1 October 2017

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A summary of the measured pK values of the ionizable groups in folded proteins

29 June 2018

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29 June 2018

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29 June 2018

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Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs

29 June 2018

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29 June 2018

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The role of astrocytes in amyloid β-protein toxicity and clearance

29 June 2018

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ANS binding reveals common features of cytotoxic amyloid species

22 September 2018

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Modulation filtering enables removal of spikes in fluorescence correlation spectroscopy measurements without affecting the temporal information

22 September 2018

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Effects of the Arctic (E22-->G) mutation on amyloid beta-protein folding: discrete molecular dynamics study

22 September 2018

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Zinc-amyloid beta interactions on a millisecond time-scale stabilize non-fibrillar Alzheimer-related species.

22 September 2018

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Insight into the kinetic of amyloid beta (1-42) peptide self-aggregation: elucidation of inhibitors' mechanism of action

22 September 2018

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22 September 2018

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Unique physicochemical profile of beta-amyloid peptide variant Abeta1-40E22G protofibrils: conceivable neuropathogen in arctic mutant carriers

22 September 2018

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Dimethylamino-fluorenes: ligands for detecting beta-amyloid plaques in the brain

22 September 2018

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Structural and dynamic features of Alzheimer's Abeta peptide in amyloid fibrils studied by site-directed spin labeling.

22 September 2018

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Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

22 September 2018

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Alternate aggregation pathways of the Alzheimer beta-amyloid peptide. An in vitro model of preamyloid.

22 September 2018

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Rational Design of β-Sheet Ligands Against Aβ42-Induced Toxicity

22 September 2018

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Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates

5 December 2018

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12 December 2020

The Alzheimer β-peptide shows temperature-dependent transitions between left-handed 31-helix, β-strand and random coil secondary structures

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12 December 2020

Zinc Lowers Amyloid-β Toxicity by Selectively Precipitating Aggregation Intermediates†

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12 December 2020

Solution conformations and aggregational properties of synthetic amyloid beta-peptides of Alzheimer's disease. Analysis of circular dichroism spectra

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12 December 2020

Simultaneous measurement of a range of particle sizes during Aβ1–42 fibrillogenesis quantified using fluorescence correlation spectroscopy

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12 December 2020

10.1016/J.BBAPAP.2015.09.002

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release_2k6p5sykyncafm76v56vosjzlm

2 June 2020

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24 November 2022

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2 June 2020

PubMed publication ID

26374940

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