Cytosol-endoplasmic reticulum interplay by Sec61alpha translocon in polyglutamine-mediated neurotoxicity in Drosophila (Q36161562)

12 August 2017

Cytosol-endoplasmic reticulum interplay by Sec61alpha translocon in polyglutamine-mediated neurotoxicity in Drosophila (English)

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12 August 2017

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endoplasmic reticulum

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6

Hideyuki Okano

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12 August 2017

Hirotaka Kanuka

1

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12 August 2017

Erina Kuranaga

2

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12 August 2017

Tetsuo Hiratou

3

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12 August 2017

Tatsushi Igaki

4

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12 August 2017

Bryce Nelson

5

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12 August 2017

Masayuki Miura

7

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12 August 2017

language of work or name

English

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publication date

22 September 2003

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Proceedings of the National Academy of Sciences of the United States of America

12 August 2017

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12 August 2017

100

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12 August 2017

20

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12 August 2017

11723-11728

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Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48.

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208825

The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208825

Analysis of Drosophila 26 S proteasome using RNA interference

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208825

Proteasomes and ubiquitin are involved in the turnover of the wild-type prion protein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208825

An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208825

Impairment of the ubiquitin-proteasome system by protein aggregation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208825

Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208825

Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208825

Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208825

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208825

Modeling human neurodegenerative diseases in Drosophila: on a wing and a prayer.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208825

Drob-1, a Drosophila member of the Bcl-2/CED-9 family that promotes cell death

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208825

The engagement of Sec61p in the ER dislocation process

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208825

Control of the cell death pathway by Dapaf-1, a Drosophila Apaf-1/CED-4-related caspase activator

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208825

Caspase activation during apoptotic cell death induced by expanded polyglutamine in N2a cells.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208825

Flamingo, a seven-pass transmembrane cadherin, regulates planar cell polarity under the control of Frizzled

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208825

Retrograde protein translocation: ERADication of secretory proteins in health and disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208825

A transmembrane form of the prion protein in neurodegenerative disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208825

Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208825

Induction of apoptosis in a Drosophila neuronal cell line by calcium ionophore

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208825

Protein translocation into proteoliposomes reconstituted from purified components of the endoplasmic reticulum membrane

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208825

The gene search system. A method for efficient detection and rapid molecular identification of genes in Drosophila melanogaster

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208825

Polypeptide translocation: a pretty picture is worth a thousand words

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=208825

Functional DNA array' in the fly: implication for neuronal degeneration.

2 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934748100

Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934748100

Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934748100

Heritable gene silencing in Drosophila using double-stranded RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934748100

Identification of genes that modify ataxin-1-induced neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934748100

Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934748100

Identification of ter94, Drosophila VCP, as a modulator of polyglutamine-induced neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934748100

Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934748100

Conversion of PrP to a self-perpetuating PrPSc-like conformation in the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934748100

Oligomeric Rings of the Sec61p Complex Induced by Ligands Required for Protein Translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1934748100

21 January 2018

Identifiers

DOI

10.1073/PNAS.1934748100

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12 August 2017

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12 August 2017

PubMed publication ID

14504396

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