Epidermal growth factor receptor inhibits colitis-associated cancer in mice (Q36129106)

12 August 2017

Epidermal growth factor receptor inhibits colitis-associated cancer in mice (English)

1 reference

12 August 2017

Philip E Dubé

1

1 reference

12 August 2017

Fang Yan

2

1 reference

12 August 2017

Shivesh Punit

3

1 reference

12 August 2017

Nandini Girish

4

1 reference

12 August 2017

Steven J McElroy

5

1 reference

12 August 2017

M Kay Washington

6

1 reference

12 August 2017

D Brent Polk

7

1 reference

12 August 2017

language of work or name

English

0 references

publication date

9 July 2012

1 reference

Journal of Clinical Investigation

12 August 2017

1 reference

12 August 2017

122

1 reference

12 August 2017

8

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12 August 2017

2780-2792

1 reference

describes a project that uses

12 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3408743/fullTextXML

inferred from PubMed Central ID database lookup

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IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer

2 October 2017

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Crypt stem cells as the cells-of-origin of intestinal cancer

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Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis.

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Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors

2 October 2017

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Identification of stem cells in small intestine and colon by marker gene Lgr5

2 October 2017

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2 October 2017

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Epidermal growth factor receptor signaling is required for microadenoma formation in the mouse azoxymethane model of colonic carcinogenesis

2 October 2017

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2 October 2017

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Mutations of the BRAF gene in ulcerative colitis-related colorectal carcinoma

2 October 2017

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Kinase suppressor of Ras-1 protects intestinal epithelium from cytokine-mediated apoptosis during inflammation

2 October 2017

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Epidermal growth factor-stimulated intestinal epithelial cell migration requires Src family kinase-dependent p38 MAPK signaling

2 October 2017

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2 October 2017

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A novel inflammation‐related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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The risk of colorectal cancer in ulcerative colitis: a meta-analysis

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Tumor necrosis factor alpha regulates proliferation in a mouse intestinal cell line

2 October 2017

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Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses

2 October 2017

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Epidermal growth factor and transforming growth factor-alpha actions on the gut.

2 October 2017

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Interleukin-10-deficient mice develop chronic enterocolitis

2 October 2017

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Establishment of conditionally immortalized epithelial cell lines from both colon and small intestine of adult H-2Kb-tsA58 transgenic mice

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Dual inhibition of VEGFR and EGFR signaling reduces the incidence and size of intestinal adenomas in Apc(Min/+) mice.

2 October 2017

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TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling.

2 July 2018

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Epidermal growth factor for ulcerative colitis

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408743

Epidermal growth factor enemas with oral mesalamine for mild-to-moderate left-sided ulcerative colitis or proctitis

2 July 2018

1 reference

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The epidermal growth factor receptor (EGF-R) is present on the basolateral, but not the apical, surface of enterocytes in the human gastrointestinal tract

2 July 2018

1 reference

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Clinical course of colorectal cancer in patients with ulcerative colitis

2 July 2018

1 reference

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Relative role of methylator and tumor suppressor pathways in ulcerative colitis-associated colon cancer

23 September 2018

1 reference

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Epidermal growth factor competes with EGF receptor inhibitors to induce cell death in EGFR-overexpressing tumor cells

23 September 2018

1 reference

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Interleukin 10 (IL-10) gene variants and susceptibility for paediatric onset Crohn's disease

23 September 2018

1 reference

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Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408743

Risk of intestinal cancer in inflammatory bowel disease: a population-based study from olmsted county, Minnesota

23 September 2018

1 reference

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Wa5 is a novel ENU-induced antimorphic allele of the epidermal growth factor receptor

23 September 2018

1 reference

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BRAF gene is somatically mutated but does not make a major contribution to malignant melanoma susceptibility: the Italian Melanoma Intergroup Study

23 September 2018

1 reference

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Progression of flat low-grade dysplasia to advanced neoplasia in patients with ulcerative colitis

23 September 2018

1 reference

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Evidence for the expression of the EGF receptor on human monocytic cells

23 September 2018

1 reference

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EGF regulates early embryonic mouse gut development in chemically defined organ culture.

23 September 2018

1 reference

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Interleukin 10-deficient colitis: new similarities to human inflammatory bowel disease.

23 September 2018

1 reference

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Azoxymethane-induced colon tumors and aberrant crypt foci in mice of different genetic susceptibility

23 September 2018

1 reference

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The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase

23 September 2018

1 reference

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The effect of epidermal growth factor (EGF) on cell proliferation of the gastrointestinal mucosa in rodents

23 September 2018

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12 December 2020

Induction of a novel epidermal growth factor-secreting cell lineage by mucosal ulceration in human gastrointestinal stem cells

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12 December 2020

Expression of growth factor receptor-encoded mRNA by colonic epithelial cells is altered in inflammatory bowel disease

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12 December 2020

Expression of transforming growth factors alpha and beta in colonic mucosa in inflammatory bowel disease

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12 December 2020

A defective EGF-receptor in waved-2 mice attenuates intestinal adaptation

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12 December 2020

The fate of low grade dysplasia in ulcerative colitis

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12 December 2020

Flat Colorectal Cancers Are Genetically Determined and Progress to Invasion without Going through a Polypoid Stage

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12 December 2020

Infant colitis—it's in the genes

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12 December 2020

Epidermal growth factor receptor signaling is up-regulated in human colonic aberrant crypt foci

1 reference

12 December 2020

Expression of epidermal growth factor receptor (EGFR) is frequent in inflammatory bowel disease (IBD)-associated intestinal cancer

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12 December 2020

Ulcerative colitis-associated colorectal cancer shows a poorer survival than sporadic colorectal cancer: a nationwide Japanese study

1 reference

12 December 2020

Intestinal Cancer Risk in Crohn’s Disease: A Meta-Analysis

1 reference

12 December 2020

1 reference

12 December 2020

Interleukin 21 controls tumour growth and tumour immunosurveillance in colitis-associated tumorigenesis in mice

1 reference

12 December 2020

Mice harboring a defective epidermal growth factor receptor (waved-2) have an increased susceptibility to acute dextran sulfate-induced colitis

1 reference

12 December 2020

Epidermal growth factor receptor immunohistochemical reactivity in patients with American Joint Committee on Cancer Stage IV colon adenocarcinoma: implications for a standardized scoring system

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12 December 2020

Identifiers

DOI

10.1172/JCI62888

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

22772467

1 reference