Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy. (Q36042441)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22737280%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

title

Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy (English)

1 reference

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6 February 2020

1 reference

19

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6 February 2020

John Streicher

20

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6 February 2020

Laura M. Bohn

23

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6 February 2020

Jeffrey Aubé

25

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6 February 2020

21

Marc G Caron

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6 February 2020

author name string

Kevin J Frankowski

1

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Michael P Hedrick

2

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Palak Gosalia

3

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Kelin Li

4

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Shenghua Shi

5

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David Whipple

6

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Partha Ghosh

7

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Thomas E Prisinzano

8

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Frank J Schoenen

9

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Ying Su

10

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S Vasile

11

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Eduard Sergienko

12

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Wilson Gray

13

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Santosh Hariharan

14

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Loribelle Milan

15

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Susanne Heynen-Genel

16

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Arianna Mangravita-Novo

17

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Michael Vicchiarelli

18

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Lawrence S Barak

22

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Thomas D Y Chung

24

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publication date

20 January 2012

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ACS Chemical Neuroscience

6 February 2020

published in

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volume

3

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6 February 2020

issue

3

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6 February 2020

page(s)

221-236

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A κ Opioid Pharmacophore Becomes a Spinally Selective κ-δ Agonist When Modified with a Basic Extender Arm.

6 February 2020

cites work

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2 October 2017

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2 October 2017

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2 October 2017

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Prolonged kappa opioid receptor phosphorylation mediated by G-protein receptor kinase underlies sustained analgesic tolerance

2 October 2017

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Antidepressant-like effects of kappa-opioid receptor antagonists in the forced swim test in rats

2 October 2017

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2 October 2017

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2 October 2017

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23 September 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/22737280

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/CN200128X

1 reference

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6 February 2020

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6 February 2020

PubMed publication ID

22737280

1 reference

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