The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions. (Q36038807)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21774078%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions (English)

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8 February 2020

1

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8 February 2020

Paul Quax

19

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8 February 2020

author name string

Torsten Hoffmann

2

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8 February 2020

Daniel Friedrich

3

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8 February 2020

Astrid Kehlen

4

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8 February 2020

Kathrin Gans

5

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8 February 2020

Martin Kleinschmidt

6

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8 February 2020

Jens-Ulrich Rahfeld

7

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8 February 2020

Raik Wolf

8

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8 February 2020

Michael Wermann

9

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8 February 2020

Anett Stephan

10

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8 February 2020

Monique Haegele

11

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8 February 2020

Reinhard Sedlmeier

12

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Sigrid Graubner

13

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Wolfgang Jagla

14

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Anke Müller

15

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8 February 2020

Rico Eichentopf

16

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8 February 2020

Ulrich Heiser

17

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8 February 2020

Franziska Seifert

18

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8 February 2020

Margreet R de Vries

20

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Isabel Hesse

21

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Daniela Trautwein

22

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Ulrich Wollert

23

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8 February 2020

Sabine Berg

24

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8 February 2020

Ernst-Joachim Freyse

25

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Stephan Schilling

26

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Hans-Ulrich Demuth

27

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publication date

20 July 2011

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8 February 2020

published in

EMBO Molecular Medicine

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8 February 2020

volume

3

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issue

9

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8 February 2020

page(s)

545-558

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Glutaminyl cyclase knock-out mice exhibit slight hypothyroidism but no hypogonadism: implications for enzyme function and drug development

8 February 2020

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Glutaminyl cyclase contributes to the formation of focal and diffuse pyroglutamate (pGlu)-Aβ deposits in hippocampus via distinct cellular mechanisms

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Isolation of an isoenzyme of human glutaminyl cyclase: retention in the Golgi complex suggests involvement in the protein maturation machinery

2 October 2017

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Inhibition of glutaminyl cyclase alters pyroglutamate formation in mammalian cells

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Identification of human glutaminyl cyclase as a metalloenzyme. Potent inhibition by imidazole derivatives and heterocyclic chelators

2 October 2017

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The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism

2 October 2017

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2 October 2017

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Heterologous expression and characterization of human glutaminyl cyclase: evidence for a disulfide bond with importance for catalytic activity

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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11 July 2018

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CCL2/Monocyte Chemoattractant Protein-1 regulates inflammatory responses critical to healing myocardial infarcts.

21 January 2018

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Developmental expression and subcellular localization of glutaminyl cyclase in mouse brain

21 January 2018

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Anti-monocyte chemoattractant protein-1 gene therapy attenuates pulmonary fibrosis in mice

21 January 2018

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Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice

21 January 2018

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Essential role of monocyte chemoattractant protein-1 in development of restenotic changes (neointimal hyperplasia and constrictive remodeling) after balloon angioplasty in hypercholesterolemic rabbits

21 January 2018

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New anti-monocyte chemoattractant protein-1 gene therapy attenuates atherosclerosis in apolipoprotein E-knockout mice

21 January 2018

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Glutaminyl cyclase inhibition attenuates pyroglutamate Abeta and Alzheimer's disease-like pathology

21 January 2018

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Glutaminyl cyclases display significant catalytic proficiency for glutamyl substrates

21 January 2018

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Mammalian glutaminyl cyclases and their isoenzymes have identical enzymatic characteristics

21 January 2018

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Gene therapy via blockade of monocyte chemoattractant protein-1 for renal fibrosis.

21 January 2018

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Anti-monocyte chemoattractant protein-1 gene therapy inhibits restenotic changes (neointimal hyperplasia) after balloon injury in rats and monkeys

21 January 2018

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Posttranslational modifications affect the activity of the human monocyte chemotactic proteins MCP-1 and MCP-2: identification of MCP-2(6-76) as a natural chemokine inhibitor.

23 September 2018

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Structure/activity analysis of human monocyte chemoattractant protein-1 (MCP-1) by mutagenesis. Identification of a mutated protein that inhibits MCP-1-mediated monocyte chemotaxis.

23 September 2018

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The Role of CD26/DPP IV in Chemokine Processing

23 September 2018

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Expression of a Human Mutant Monocyte Chemotactic Protein 3 in Pichia pastoris and Characterization as an MCP-3 Receptor Antagonist

21 January 2018

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21 January 2018

2 references

PubMed

https://pubmed.ncbi.nlm.nih.gov/21774078

12 December 2020

inferred from PubMed ID database lookup

https://api.crossref.org/works/10.1002%2FEMMM.201100158

7 January 2021

inferred from DOI database lookup

Glutaminyl-cyclase expression in the bovine/porcine hypothalamus and pituitary

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21774078

12 December 2020

inferred from PubMed ID database lookup

Leukocyte subpopulations and arteriogenesis: specific role of monocytes, lymphocytes and granulocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21774078

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1002/EMMM.201100158

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21774078%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

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8 February 2020

PubMed publication ID

21774078

1 reference