Understanding the response to immunotherapy in humans (Q36017877)

11 August 2017

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title

Understanding the response to immunotherapy in humans (English)

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11 August 2017

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3

Francesco M Marincola

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11 August 2017

Ena Wang

1

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11 August 2017

Monica C Panelli

series ordinal

2

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11 August 2017

publication date

22 January 2005

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Seminars in Immunopathology

11 August 2017

published in

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11 August 2017

volume

27

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11 August 2017

issue

1

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11 August 2017

page(s)

105-117

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Phenotypic and Functional Separation of Memory and Effector Human CD8+ T Cells

11 August 2017

cites work

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Translational Medicine: A two-way road

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Expansion and functional maturation of human tumor antigen-specific CD8+ T cells after vaccination with antigenic peptide.

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Tumor antigens recognized by T lymphocytes

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Cancer immunoediting: from immunosurveillance to tumor escape

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Cancer immunotherapy with peptide-based vaccines: what have we achieved? Where are we going?

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Status of activation of circulating vaccine-elicited CD8+ T cells

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Expansion of melanoma-specific cytolytic CD8+ T cell precursors in patients with metastatic melanoma vaccinated with CD34+ progenitor-derived dendritic cells

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Natural selection of tumor variants in the generation of "tumor escape" phenotypes

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Immune surveillance against a solid tumor fails because of immunological ignorance

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Dendritic cells loaded with killed breast cancer cells induce differentiation of tumor-specific cytotoxic T lymphocytes

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Escape of human solid tumors from T-cell recognition: molecular mechanisms and functional significance.

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Ex vivo analysis of tumor antigen specific CD8+ T cell responses using MHC/peptide tetramers in cancer patients

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12 December 2020

Tumors as elusive targets of T-cell-based active immunotherapy

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12 December 2020

Increased vaccine-specific T cell frequency after peptide-based vaccination correlates with increased susceptibility to in vitro stimulation but does not lead to tumor regression

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12 December 2020

A modified human ELISPOT assay to detect specific responses to primary tumor cell targets

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12 December 2020

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Experience with the use of high-dose interleukin-2 in the treatment of 652 cancer patients

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Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections

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A genomic- and proteomic-based hypothesis on the eclectic effects of systemic interleukin-2 administration in the context of melanoma-specific immunization

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T-cell clonotypes in cancer

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Short-term kinetics of tumor antigen expression in response to vaccination

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Intensity of the vaccine-elicited immune response determines tumor clearance

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Evaluation of melanoma vaccines with molecularly defined antigens by ex vivo monitoring of tumor-specific T cells

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Polymorphism in clinical immunology - From HLA typing to immunogenetic profiling

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Peptide vaccine trials for melanoma: preclinical background and clinical results

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Vaccination with mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma

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12 December 2020

Prospective molecular profiling of melanoma metastases suggests classifiers of immune responsiveness.

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12 December 2020

Alterations in T cell receptor and signal transduction molecules in melanoma patients

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12 December 2020

HLA associations in the antitumor response against malignant melanoma.

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12 December 2020

Local delivery of poxvirus vaccines for melanoma

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Enhancement of antitumor immunity by CTLA-4 blockade

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New Paths in Human Cancer Serology

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12 December 2020

Genetic instabilities in human cancers

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Gene polymorphisms, inflammatory diseases and cancer

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12 December 2020

Vaccination of Metastatic Melanoma Patients With Autologous Tumor-Derived Heat Shock Protein gp96-Peptide Complexes: Clinical and Immunologic Findings

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Stringent allele/epitope requirements for MART-1/Melan A immunodominance: implications for peptide-based immunotherapy.

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12 December 2020

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12 December 2020

Gene expression profiling of anticancer immune responses.

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Localization of 111indium-labeled tumor infiltrating lymphocytes to tumor in patients receiving adoptive immunotherapy. Augmentation with cyclophosphamide and correlation with response

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Molecular and functional profiling of memory CD8 T cell differentiation.

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12 December 2020

Functional heterogeneity of vaccine-induced CD8(+) T cells

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12 December 2020

Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

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12 December 2020

Quiescent phenotype of tumor-specific CD8+ T cells following immunization

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12 December 2020

Immunotherapy of melanoma

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12 December 2020

Ex vivo IFN-gamma secretion by circulating CD8 T lymphocytes: implications of a novel approach for T cell monitoring in infectious and malignant diseases

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Synopsis of the 6th Walker's Cay Colloquium on Cancer Vaccines and Immunotherapy

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12 December 2020

Skewed maturation of memory HIV-specific CD8 T lymphocytes

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12 December 2020

Immunotherapy of melanoma: the good news, the bad ones and what to do next

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12 December 2020

Phase 2 trial of vaccination with tyrosinase peptides and granulocyte-macrophage colony-stimulating factor in patients with metastatic melanoma.

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12 December 2020

Lysis of human melanoma cells by autologous cytolytic T cell clones. Identification of human histocompatibility leukocyte antigen A2 as a restriction element for three different antigens

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12 December 2020

Kinetics of TCR use in response to repeated epitope-specific immunization

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12 December 2020

Overview of melanoma vaccines and promising approaches

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12 December 2020

Failing immune control as a result of impaired CD8+ T-cell maturation: CD27 might provide a clue

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12 December 2020

Cancer vaccines based on the identification of genes encoding cancer regression antigens

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12 December 2020

CD8 T Cell Clonal Expansion and Development of Effector Function Require Prolonged Exposure to Antigen, Costimulation, and Signal 3 Cytokine

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12 December 2020

Rational peptide-based tumour vaccine development and T cell monitoring

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12 December 2020

HLA-DQB1*0301 association with increased cutaneous melanoma risk

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12 December 2020

A natural history of melanoma: serial gene expression analysis

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12 December 2020

Immunodominance across HLA polymorphism: implications for cancer immunotherapy

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12 December 2020

Forecasting the cytokine storm following systemic interleukin (IL)-2 administration

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12 December 2020

HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors

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12 December 2020

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12 December 2020

Is cancer dangerous to the immune system?

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12 December 2020

Dendritic cells as vectors for immunotherapy of cancer

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12 December 2020

Biased epitope selection by recombinant vaccinia-virus (rVV)-infected mature or immature dendritic cells

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12 December 2020

Immunization of patients with metastatic melanoma using both class I- and class II-restricted peptides from melanoma-associated antigens

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12 December 2020

The Granzyme B ELISPOT assay: an alternative to the 51Cr-release assay for monitoring cell-mediated cytotoxicity

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12 December 2020

Epitope spreading in immune-mediated diseases: implications for immunotherapy

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12 December 2020

Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients

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12 December 2020

Tumor antigens recognized by T cells

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12 December 2020

Vaccination with irradiated autologous tumor cells engineered to secrete granulocyte-macrophage colony-stimulating factor augments antitumor immunity in some patients with metastatic non-small-cell lung carcinoma

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12 December 2020

Introduction to the series. Danger model of immunity

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12 December 2020

Results of clinical trials with an allogenic melanoma tumor cell lysate vaccine: Melacine

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12 December 2020

Gene-expression profiling of the response of peripheral blood mononuclear cells and melanoma metastases to systemic IL-2 administration

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12 December 2020

A strategy for detection of known and unknown SNP using a minimum number of oligonucleotides applicable in the clinical settings

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12 December 2020

The activatory receptor 2B4 is expressed in vivo by human CD8+ effector alpha beta T cells

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12 December 2020

The dual role of IL-10.

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12 December 2020

Human tumor-derived heat shock protein 96 mediates in vitro activation and in vivo expansion of melanoma- and colon carcinoma-specific T cells.

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12 December 2020

Lost in Translation: Obstacles to Translational Medicine

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12 December 2020

HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function

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12 December 2020

Active-specific immunization against melanoma: is the problem at the receiving end?

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12 December 2020

Extra-lymphatic solid tumor growth is not immunologically ignored and results in early induction of antigen-specific T-cell anergy: dominant role of cross-tolerance to tumor antigens

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12 December 2020

In vivo activation of melanoma-specific CD8(+) T cells by endogenous tumor antigen and peptide vaccines. A comparison to virus-specific T cells

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12 December 2020

Functional analysis of antigen-specific T lymphocytes by serial measurement of gene expression in peripheral blood mononuclear cells and tumor specimens

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12 December 2020

Influence of vascular endothelial growth factor single nucleotide polymorphisms on tumour development in cutaneous malignant melanoma

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12 December 2020

Lineage relationship and protective immunity of memory CD8 T cell subsets

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12 December 2020

Expansion of tumor-T cell pairs from fine needle aspirates of melanoma metastases

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12 December 2020

10.1007/S00281-004-0198-7

Identifiers

DOI

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11 August 2017

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