Body weight is regulated by the brain: a link between feeding and emotion (Q35998749)

11 August 2017

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title

Body weight is regulated by the brain: a link between feeding and emotion (English)

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11 August 2017

Kishi T

1

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11 August 2017

Elmquist JK

series ordinal

2

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11 August 2017

language of work or name

English

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publication date

1 February 2005

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11 August 2017

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11 August 2017

volume

10

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11 August 2017

issue

2

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11 August 2017

page(s)

132-146

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Obesity in the new millennium

11 August 2017

cites work

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

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7 January 2021

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7 January 2021

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7 January 2021

Identification of targets of leptin action in rat hypothalamus

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Leptin increases hypothalamic pro-opiomelanocortin mRNA expression in the rostral arcuate nucleus.

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7 January 2021

Hypothalamic Pro-Opiomelanocortin mRNA Is Reduced By Fasting in ob/ob and db/db Mice, but Is Stimulated by Leptin

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7 January 2021

Melanocortin receptors weigh in.

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7 January 2021

Expression of melanocortin 4 receptor mRNA in the central nervous system of the rat.

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7 January 2021

Transgenic mice expressing green fluorescent protein under the control of the melanocortin-4 receptor promoter.

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7 January 2021

Targeted disruption of the melanocortin-4 receptor results in obesity in mice

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7 January 2021

A frameshift mutation in human MC4R is associated with a dominant form of obesity

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7 January 2021

A frameshift mutation in MC4R associated with dominantly inherited human obesity

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7 January 2021

Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency

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7 January 2021

Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity

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7 January 2021

Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene

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7 January 2021

Intracellular retention is a common characteristic of childhood obesity-associated MC4R mutations

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7 January 2021

Mutations in the human melanocortin-4 receptor gene associated with severe familial obesity disrupts receptor function through multiple molecular mechanisms

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7 January 2021

Genetics of body-weight regulation

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7 January 2021

Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

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7 January 2021

Mutations in the human proopiomelanocortin gene

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7 January 2021

Hypothalamic expression of ART, a novel gene related to agouti, is up-regulated in obese and diabetic mutant mice

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7 January 2021

Overexpression of Agrt leads to obesity in transgenic mice

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7 January 2021

Antagonism of Central Melanocortin Receptors in Vitro and in Vivo by Agouti-Related Protein

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7 January 2021

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7 January 2021

Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons

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7 January 2021

Melanocortin receptors in leptin effects

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7 January 2021

Satiety effect and sympathetic activation of leptin are mediated by hypothalamic melanocortin system

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7 January 2021

Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis

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7 January 2021

Independent and Additive Effects of Central POMC and Leptin Pathways on Murine Obesity

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7 January 2021

Response of melanocortin-4 receptor-deficient mice to anorectic and orexigenic peptides.

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7 January 2021

The presence of two α-MSH positive cell groups in rat hypothalamus

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7 January 2021

Anatomy of an endogenous antagonist: relationship between Agouti-related protein and proopiomelanocortin in brain.

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7 January 2021

Feeding effects of hypothalamic injection of melanocortin 4 receptor ligands

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7 January 2021

Paraventricular hypothalamic alpha-melanocyte-stimulating hormone and MTII reduce feeding without causing aversive effects.

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7 January 2021

ARC POMC mRNA and PVN alpha-MSH are lower in obese relative to lean zucker rats.

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7 January 2021

Hypothalamic Integration: Organization of the Paraventricular and Supraoptic Nuclei

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7 January 2021

Interaction between alpha-melanocyte-stimulating hormone and corticotropin-releasing hormone in the regulation of feeding and hypothalamo-pituitary-adrenal responses.

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7 January 2021

Transcriptional regulation of the thyrotropin-releasing hormone gene by leptin and melanocortin signaling

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7 January 2021

alpha-Melanocyte-stimulating hormone is contained in nerve terminals innervating thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and prevents fasting-induced suppression of prothyrotropin-releasing [...]

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7 January 2021

Effect of Agouti-related protein in regulation of the hypothalamic-pituitary-thyroid axis in the melanocortin 4 receptor knockout mouse

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7 January 2021

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7 January 2021

A role for melanin-concentrating hormone in the central regulation of feeding behaviour

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7 January 2021

Mice lacking melanin-concentrating hormone are hypophagic and lean

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7 January 2021

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

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7 January 2021

The distribution of the mRNA and protein products of the melanin-concentrating hormone (MCH) receptor gene, slc-1, in the central nervous system of the rat.

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7 January 2021

Differential expression of orexin receptors 1 and 2 in the rat brain

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7 January 2021

Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R

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7 January 2021

Expression of the melanin-concentrating hormone (MCH) receptor mRNA in the rat brain

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7 January 2021

Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance

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7 January 2021

Melanin-concentrating hormone is a critical mediator of the leptin-deficient phenotype

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7 January 2021

Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation

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7 January 2021

The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene

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7 January 2021

Hypocretin (orexin) deficiency in human narcolepsy.

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7 January 2021

Sleeping with the hypothalamus: emerging therapeutic targets for sleep disorders

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7 January 2021

The sleep switch: hypothalamic control of sleep and wakefulness

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7 January 2021

Roles of orexins in regulation of feeding and wakefulness

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7 January 2021

Physiological properties of hypothalamic MCH neurons identified with selective expression of reporter gene after recombinant virus infection

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7 January 2021

Integration of NPY, AGRP, and melanocortin signals in the hypothalamic paraventricular nucleus: evidence of a cellular basis for the adipostat

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7 January 2021

Tonic inhibition of food intake during inactive phase is reversed by the injection of the melanocortin receptor antagonist into the paraventricular nucleus of the hypothalamus and central amygdala of the rat.

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7 January 2021

Central melanocortin receptors regulate insulin action

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7 January 2021

Hypothalamic insulin signaling is required for inhibition of glucose production

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7 January 2021

Rethinking the central causes of diabetes

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7 January 2021

Recombinant adeno-associated virus vector: use for transgene expression and anterograde tract tracing in the CNS

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7 January 2021

A unique metabolic syndrome causes obesity in the melanocortin-3 receptor-deficient mouse

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7 January 2021

Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass

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7 January 2021

Y-receptor subtypes--how many more?

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7 January 2021

Neuropeptide Y: some viewpoints on a multifaceted peptide in the normal and diseased nervous system

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Neuropeptide Y feeding receptors: are multiple subtypes involved?

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Neuropeptide Y Distribution in the Rat Brain

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7 January 2021

The anatomy of neuropeptide-Y-containing neurons in rat brain

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7 January 2021

Molecular cloning of a novel G protein-coupled receptor that may belong to the neuropeptide receptor family

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7 January 2021

Role of the Y1 receptor in the regulation of neuropeptide Y-mediated feeding: comparison of wild-type, Y1 receptor-deficient, and Y5 receptor-deficient mice

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7 January 2021

Gut hormone PYY(3-36) physiologically inhibits food intake

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Important role of hypothalamic Y2 receptors in body weight regulation revealed in conditional knockout mice

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

A receptor subtype involved in neuropeptide-Y-induced food intake

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Orexin-induced food intake involves neuropeptide Y pathway

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Obesity and mild hyperinsulinemia found in neuropeptide Y-Y1 receptor-deficient mice

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7 January 2021

Cardiovascular response, feeding behavior and locomotor activity in mice lacking the NPY Y1 receptor

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Neither agouti-related protein nor neuropeptide Y is critically required for the regulation of energy homeostasis in mice

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y.

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7 January 2021

Ghrelin induces adiposity in rodents

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7 January 2021

The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis

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7 January 2021

Orexigenic action of peripheral ghrelin is mediated by neuropeptide Y and agouti-related protein

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7 January 2021

Genetic deletion of ghrelin does not decrease food intake but influences metabolic fuel preference

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7 January 2021

Complementary and overlapping expression of Y1, Y2 and Y5 receptors in the developing and adult mouse nervous system.

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7 January 2021

Expression of the neuropeptide Y Y1 receptor in the CNS of rat and of wild-type and Y1 receptor knock-out mice. Focus on immunohistochemical localization

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7 January 2021

Neuropeptide Y Y1 receptor mRNA in rodent brain: distribution and colocalization with melanocortin-4 receptor

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7 January 2021

Adiposity signals and brain reward mechanisms.

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7 January 2021

Behavior-relevant changes in nucleus accumbens dopamine transmission elicited by food reinforcement: an electrochemical study in rat.

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7 January 2021

Opioid receptor involvement in the effect of AgRP- (83-132) on food intake and food selection.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Reversal of cancer anorexia by blockade of central melanocortin receptors in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Mu, delta, and kappa opioid receptor mRNA expression in the rat CNS: an in situ hybridization study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Opiate Effects After Adrenocorticotropin or β-Endorphin Injection in the Periaqueductal Gray Matter of Rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Selective reward deficit in mice lacking beta-endorphin and enkephalin.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Anatomically distinct opiate receptor fields mediate reward and physical dependence

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Ethanol consumption and resistance are inversely related to neuropeptide Y levels

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Voluntary alcohol consumption is controlled via the neuropeptide Y Y1 receptor.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Opioids and alcoholism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Selective melanocortin MC4 receptor blockage reduces immobilization stress-induced anorexia in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Involvement of the melanocortin MC4 receptor in stress-related behavior in rodents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Neurobiology of depression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Emerging experimental therapeutics for bipolar disorder: clues from the molecular pathophysiology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Electrophysiological effects of melanocortin receptor ligands on neuronal activities of monoaminergic neurons in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Serotoninergic endings on VIP-neurons in the suprachiasmatic nucleus and on ACTH-neurons in the arcuate nucleus of the rat hypothalamus. A combination of high resolution autoradiography and electron microscopic immunocytochemistry

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Activation of central melanocortin pathways by fenfluramine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Central serotonin and melanocortin pathways regulating energy homeostasis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Valvular heart disease associated with fenfluramine-phentermine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Anatomic relationships of the human arcuate nucleus of the medulla: a DiI-labeling study.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Arcuate nucleus projections to brainstem regions which modulate nociception

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

New insights into sympathetic regulation of glucose and fat metabolism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Serotonin receptors: their key role in drugs to treat schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Pronounced early increase in circulating leptin predicts a lower weight gain during clozapine treatment.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Rat diencephalic neurons producing melanin-concentrating hormone are influenced by ascending cholinergic projections

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Mice lacking the M3 muscarinic acetylcholine receptor are hypophagic and lean.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Ascending projections from the pedunculopontine tegmental nucleus and the adjacent mesopontine tegmentum in the rat

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Topographical organization of projections from the subiculum to the hypothalamus in the rat

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Distribution of ionotropic glutamate receptor subunit mRNAs in the rat hypothalamus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Localization of Neuropeptide Y Y1 mRNA in the Human Brain: Abundant Expression in Cerebral Cortex and Striatum

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Modulation of anxiety and neuropeptide Y-Y1 receptors by antisense oligodeoxynucleotides

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Behavioral insensitivity to restraint stress, absent fear suppression of behavior and impaired spatial learning in transgenic rats with hippocampal neuropeptide Y overexpression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Genes, dopamine and cortical signal-to-noise ratio in schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Identification of receptors for neuromedin U and its role in feeding

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Neuromedin U and Neuromedin U receptor-2 expression in the mouse and rat hypothalamus: effects of nutritional status.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001638

7 January 2021

Identifiers

DOI

10.1038/SJ.MP.4001638

1 reference

11 August 2017

1 reference