Humanized Tau Mice with Regionalized Amyloid Exhibit Behavioral Deficits but No Pathological Interaction (Q35986968)

11 August 2017

Humanized Tau Mice with Regionalized Amyloid Exhibit Behavioral Deficits but No Pathological Interaction (English)

1 reference

11 August 2017

Michael J Yetman

1

1 reference

11 August 2017

Stephanie W Fowler

series ordinal

2

1 reference

11 August 2017

Joanna L Jankowsky

series ordinal

3

1 reference

11 August 2017

language of work or name

English

0 references

publication date

12 April 2016

1 reference

11 August 2017

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11 August 2017

11

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11 August 2017

4

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11 August 2017

e0153724

1 reference

Creative Commons Attribution 4.0 International

11 August 2017

start time

12 April 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Reactive microglia drive tau pathology and contribute to the spreading of pathological tau in the brain

2 October 2017

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Tau reduction diminishes spatial learning and memory deficits after mild repetitive traumatic brain injury in mice.

2 October 2017

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2 October 2017

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Seizure resistance without parkinsonism in aged mice after tau reduction

2 October 2017

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Genetic modulation of soluble Aβ rescues cognitive and synaptic impairment in a mouse model of Alzheimer's disease

2 October 2017

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Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging

2 October 2017

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Synergistic effects of amyloid-beta and wild-type human tau on dendritic spine loss in a floxed double transgenic model of Alzheimer's disease

2 October 2017

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Effects of the C57BL/6 strain background on tauopathy progression in the rTg4510 mouse model

2 October 2017

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Modeling Alzheimer's disease in mouse without mutant protein overexpression: cooperative and independent effects of Aβ and tau

2 October 2017

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Age-appropriate cognition and subtle dopamine-independent motor deficits in aged tau knockout mice

2 October 2017

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Identification of Stk25 as a genetic modifier of Tau phosphorylation in Dab1-mutant mice

2 October 2017

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Tau reduction does not prevent motor deficits in two mouse models of Parkinson's disease

2 October 2017

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Amyloid-β/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease.

2 October 2017

1 reference

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Immunotherapy Targeting Pathological Tau Prevents Cognitive Decline in a New Tangle Mouse Model

2 October 2017

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Regulation of Tau Pathology by the Microglial Fractalkine Receptor

2 October 2017

1 reference

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Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease

2 October 2017

1 reference

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2 October 2017

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Age-dependent impairment of cognitive and synaptic function in the htau mouse model of tau pathology

2 October 2017

1 reference

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Linking Abeta and tau in late-onset Alzheimer's disease: a dual pathway hypothesis

2 October 2017

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Animal models of Alzheimer's disease and frontotemporal dementia

2 October 2017

1 reference

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Induction of tau pathology by intracerebral infusion of amyloid-beta -containing brain extract and by amyloid-beta deposition in APP x Tau transgenic mice

2 October 2017

1 reference

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Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

2 October 2017

1 reference

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Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

2 October 2017

1 reference

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Age-dependent neurofibrillary tangle formation, neuron loss, and memory impairment in a mouse model of human tauopathy (P301L).

2 October 2017

1 reference

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Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease

2 October 2017

1 reference

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The origins and uses of mouse outbred stocks

2 October 2017

1 reference

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Tau suppression in a neurodegenerative mouse model improves memory function

2 October 2017

1 reference

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Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

2 October 2017

1 reference

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Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity

2 October 2017

1 reference

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Phylogenetic diversity of the expression of the microtubule-associated protein tau: implications for neurodegenerative disorders

2 October 2017

1 reference

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Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity

2 October 2017

1 reference

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Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4829202

Effects of injected Alzheimer beta-amyloid cores in rat brain.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4829202

Neuropathological stageing of Alzheimer-related changes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4829202

Alzheimer's disease: the amyloid cascade hypothesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4829202

Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4829202

Local and distant histopathological effects of unilateral amyloid-beta 25-35 injections into the amygdala of young F344 rats

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4829202

In vivo neurotoxicity of beta-amyloid [beta(1-40)] and the beta(25-35) fragment

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4829202

Alzheimer's disease-like pathology induced by amyloid-β oligomers in nonhuman primates.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4829202

Repetitive mild traumatic brain injury augments tau pathology and glial activation in aged hTau mice

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4829202

Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4829202

Rat tau proteome consists of six tau isoforms: implication for animal models of human tauopathies

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4829202

Kinase activities increase during the development of tauopathy in htau mice.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4829202

Genetically augmenting tau levels does not modulate the onset or progression of Abeta pathology in transgenic mice

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4829202

CaMKII activation in the entorhinal cortex disrupts previously encoded spatial memory

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4829202

Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4829202

Amyloid beta-protein (Abeta)1-40 protects neurons from damage induced by Abeta1-42 in culture and in rat brain

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4829202

Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4829202

Isoforms changes of tau protein during development in various species

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4829202

Genetic modulation of tau phosphorylation in the mouse.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4829202

Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4829202

Neurotrophins are required for nerve growth during development

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4829202

Muscle weakness, hyperactivity, and impairment in fear conditioning in tau-deficient mice

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4829202

Laterality in the histological effects of injections of amyloid-beta 25-35 into the amygdala of young Fischer rats.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4829202

Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4829202

Characterization of pathology in transgenic mice over-expressing human genomic and cDNA tau transgenes

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27070146

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0153724

1 reference

11 August 2017

0 references

1 reference

11 August 2017

PubMed publication ID

27070146

1 reference