Glycosphingolipid synthesis inhibition limits osteoclast activation and myeloma bone disease. (Q35899430)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25915583%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

title

Glycosphingolipid synthesis inhibition limits osteoclast activation and myeloma bone disease (English)

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Aristeidis Chaidos

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Anne Dell

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Anne Dell

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Aristotelis Antonopoulos

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Aristotelis Antonopoulos

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language of work or name

English

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publication date

27 April 2015

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Journal of Clinical Investigation

6 March 2020

published in

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volume

125

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issue

6

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page(s)

2279-2292

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describes a project that uses

6 March 2020

ImageJ

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11 June 2022

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inferred from PubMed Central ID database lookup

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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Membrane rafts play a crucial role in receptor activator of nuclear factor kappaB signaling and osteoclast function

11 July 2018

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Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts

11 July 2018

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Ganglioside GM3 activates ERKs in human lymphocytic cells.

11 July 2018

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Antisense inhibition of macrophage inflammatory protein 1-alpha blocks bone destruction in a model of myeloma bone disease

11 July 2018

1 reference

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Transforming growth factor beta affects osteoclast differentiation via direct and indirect actions.

11 July 2018

1 reference

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Macrophage inflammatory protein-1alpha is an osteoclastogenic factor in myeloma that is independent of receptor activator of nuclear factor kappaB ligand

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518690

Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518690

Functional roles of glycosphingolipids in signal transduction via lipid rafts

11 July 2018

1 reference

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TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src

11 July 2018

1 reference

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TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

11 July 2018

1 reference

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N-butyldeoxynojirimycin is a novel inhibitor of glycolipid biosynthesis.

11 July 2018

1 reference

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Ganglioside GM3: an acidic membrane component that increases during macrophage-like cell differentiation can induce monocytic differentiation of human myeloid and monocytoid leukemic cell lines HL-60 and U937

11 July 2018

1 reference

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11 July 2018

1 reference

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Effect of glycosphingolipids on osteoclastogenesis and osteolytic bone diseases.

11 July 2018

1 reference

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Strontium can increase some osteoblasts without increasing hematopoietic stem cells.

24 September 2018

1 reference

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Role of IGF-I signaling in regulating osteoclastogenesis

24 September 2018

1 reference

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Ganglioside GM3 promotes cell migration by regulating MAPK and c-Fos/AP-1.

24 September 2018

1 reference

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Autoamplification of NFATc1 expression determines its essential role in bone homeostasis

24 September 2018

1 reference

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Analysis of fluorescently labeled glycosphingolipid-derived oligosaccharides following ceramide glycanase digestion and anthranilic acid labeling

24 September 2018

1 reference

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Lactosylceramide is essential for the osteoclastogenesis mediated by macrophage-colony-stimulating factor and receptor activator of nuclear factor-kappa B ligand.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518690

Increased expression of macrophage inflammatory protein-1α on trephine biopsies correlates with extensive bone disease, increased angiogenesis and advanced stage in newly diagnosed patients with multiple myeloma

24 September 2018

1 reference

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Changes in glycosphingolipid composition during differentiation of human leukemic granulocytes in chronic myelogenous leukemia compared with in vitro granulocytic differentiation of human promyelocytic leukemia cell line HL-60

14 November 2018

1 reference

12 December 2020

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12 December 2020

Characteristic expression of glycosphingolipid profiles in the bipotential cell differentiation of human promyelocytic leukemia cell line HL-60

1 reference

12 December 2020

Serum levels of macrophage inflammatory protein-1 alpha (MIP-1alpha) correlate with the extent of bone disease and survival in patients with multiple myeloma

1 reference

12 December 2020

High-Performance Cation-Exchange Chromatography and Pulsed Amperometric Detection for the Separation, Detection, and Quantitation of N-Alkylated Imino Sugars in Biological Samples

1 reference

12 December 2020

Macrophage inflammatory protein 1-alpha is a potential osteoclast stimulatory factor in multiple myeloma

1 reference

12 December 2020

Glucosylated free oligosaccharides are biomarkers of endoplasmic- reticulum α-glucosidase inhibition

1 reference

12 December 2020

Osteotropic agents regulate the expression of osteoclast differentiation factor and osteoprotegerin in osteoblastic stromal cells

1 reference

12 December 2020

Neutral glycosphingolipid expression in B-cell neoplasms

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12 December 2020

Identifiers

DOI

10.1172/JCI59987

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25915583%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25915583%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

PubMed publication ID

25915583

1 reference