Pharmacological characterization of guanidinoethyldisulphide (GED), a novel inhibitor of nitric oxide synthase with selectivity towards the inducible isoform (Q35873994)

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scientific article published in August 1996

Language	Label	Description	Also known as
English	Pharmacological characterization of guanidinoethyldisulphide (GED), a novel inhibitor of nitric oxide synthase with selectivity towards the inducible isoform	scientific article published in August 1996

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Pharmacological characterization of guanidinoethyldisulphide (GED), a novel inhibitor of nitric oxide synthase with selectivity towards the inducible isoform (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

author name string

C Szabó

1

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

R Bryk

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

B Zingarelli

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

G J Southan

4

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

T C Gahman

5

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

V Bhat

6

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

A L Salzman

7

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

D J Wolff

8

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

language of work or name

0 references

publication date

1 August 1996

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

British Journal of Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

118

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

7

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

1659-1668

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909818

11 July 2018

Spontaneous rearrangement of aminoalkylisothioureas into mercaptoalkylguanidines, a novel class of nitric oxide synthase inhibitors with selectivity towards the inducible isoform

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909818

11 July 2018

Selective pharmacological inhibition of distinct nitric oxide synthase isoforms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909818

11 July 2018

Production of immortalized distal respiratory epithelial cell lines from surfactant protein C/simian virus 40 large tumor antigen transgenic mice

1 reference

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11 July 2018

Differential regulation of constitutive and inducible nitric oxide production by inflammatory stimuli in murine endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909818

11 July 2018

Peroxynitrite induces both vasodilatation and impaired vascular relaxation in the isolated perfused rat heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909818

11 July 2018

Nifedipine inhibits the induction of nitric oxide synthase by bacterial lipopolysaccharide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909818

11 July 2018

Aminoguanidine attenuates the delayed circulatory failure and improves survival in rodent models of endotoxic shock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909818

11 July 2018

Altered immune responses in mice lacking inducible nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909818

11 July 2018

Alterations in nitric oxide production in various forms of circulatory shock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909818

11 July 2018

Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909818

11 July 2018

Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909818

11 July 2018

Modulation of in vivo alloreactivity by inhibition of inducible nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909818

11 July 2018

Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909818

11 July 2018

The inhibition of the constitutive and inducible nitric oxide synthase isoforms by indazole agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909818

11 July 2018

Inhibition of nitric oxide formation by guanidines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909818

11 July 2018

Nitric oxide synthesis in the CNS, endothelium and macrophages differs in its sensitivity to inhibition by arginine analogues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909818

11 July 2018

Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909818

11 July 2018

Nitric oxide as a secretory product of mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909818

11 July 2018

Identification and characterization of a calmodulin-dependent nitric oxide synthase from GH3 pituitary cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909818

11 July 2018

Selective inhibition of constitutive nitric oxide synthase by L-NG-nitroarginine

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.1996.TB15589.X

21 January 2018

Dexamethasone prevents vascular failure mediated by nitric oxide in hemorrhagic shock.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909818

24 September 2018

Inhibitors of brain nitric oxide synthase. Binding kinetics, metabolism, and enzyme inactivation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909818

24 September 2018

The mechanism of action of AET. IV. The distribution and the chemical forms of 2-mercaptoethylguanidine and bis(2-guanidoethyl) disulfide in protected mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/8842429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NG-Methyl-L-arginine functions as an alternate substrate and mechanism-based inhibitor of nitric oxide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8842429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8842429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

THE MECHANISM OF ACTION OF AET. V. THE DISTRIBUTION AND THE CHEMICAL FORMS OF 2-MERCAPTOETHYLGUANIDINE AND BIS (2-GUANIDOETHYL) DISULFIDE GIVEN ORALLY IN PROTECTIVE DOSES TO MICE

1 reference

https://pubmed.ncbi.nlm.nih.gov/8842429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-nitro-L-arginine and N-monomethyl-L-arginine exhibit a different pattern of inactivation toward the three nitric oxide synthases

1 reference

https://pubmed.ncbi.nlm.nih.gov/8842429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endotoxin triggers the expression of an inducible isoform of nitric oxide synthase and the formation of peroxynitrite in the rat aorta in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/8842429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The protection of mice against radiation by 2-mercaptoethylguanidine and its disulfide

1 reference

https://pubmed.ncbi.nlm.nih.gov/8842429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of nitric oxide synthase isoforms by diaminoguanidine and NG-amino-L-arginine

1 reference

https://pubmed.ncbi.nlm.nih.gov/8842429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism and radioprotective effect of AET and MEG in organism

1 reference

https://pubmed.ncbi.nlm.nih.gov/8842429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophage and endothelial cell nitric oxide synthesis: cell-type selective inhibition by NG-aminoarginine, NG-nitroarginine and NG-methylarginine

1 reference

https://pubmed.ncbi.nlm.nih.gov/8842429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inhibition of the constitutive bovine endothelial nitric oxide synthase by imidazole and indazole agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/8842429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amidines are potent inhibitors of nitric oxide synthases: preferential inhibition of the inducible isoform

1 reference

https://pubmed.ncbi.nlm.nih.gov/8842429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aminoguanidine is an isoform-selective, mechanism-based inactivator of nitric oxide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8842429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemical protection against ionizing radiation. II. Mercaptoalkylamines and related compounds with protective activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/8842429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1476-5381.1996.TB15589.X

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

ResearchGate publication ID

0 references

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