AIM2 Drives Joint Inflammation in a Self-DNA Triggered Model of Chronic Polyarthritis (Q35675556)

9 August 2017

title

AIM2 Drives Joint Inflammation in a Self-DNA Triggered Model of Chronic Polyarthritis (English)

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9 August 2017

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3

Veit Hornung

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9 August 2017

Christopher Jakobs

1

1 reference

9 August 2017

Sven Perner

series ordinal

2

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9 August 2017

language of work or name

English

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publication date

26 June 2015

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9 August 2017

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9 August 2017

volume

10

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9 August 2017

issue

6

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9 August 2017

page(s)

e0131702

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Creative Commons Attribution 4.0 International

9 August 2017

copyright license

start time

26 June 2015

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Cutting edge: AIM2 and endosomal TLRs differentially regulate arthritis and autoantibody production in DNase II-deficient mice

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12 July 2018

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Dnase2a deficiency uncovers lysosomal clearance of damaged nuclear DNA via autophagy

12 July 2018

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OAS proteins and cGAS: unifying concepts in sensing and responding to cytosolic nucleic acids

12 July 2018

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The cGAS-cGAMP-STING pathway of cytosolic DNA sensing and signaling

12 July 2018

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Interferon-stimulated genes: a complex web of host defenses

12 July 2018

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Aicardi-Goutières syndrome: a model disease for systemic autoimmunity

12 July 2018

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12 July 2018

Immune sensing of DNA

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AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC.

12 July 2018

1 reference

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Nucleic acid driven sterile inflammation

12 July 2018

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STING manifests self DNA-dependent inflammatory disease

12 July 2018

1 reference

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AIM2/ASC triggers caspase-8-dependent apoptosis in Francisella-infected caspase-1-deficient macrophages.

12 July 2018

1 reference

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Caspase-1-induced pyroptotic cell death

12 July 2018

1 reference

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The PYHIN protein family as mediators of host defenses.

12 July 2018

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Autoinflammation by endogenous DNA.

12 July 2018

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Pathogenesis of systemic juvenile idiopathic arthritis: some answers, more questions

12 July 2018

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Nucleic Acid Recognition by the Innate Immune System

12 July 2018

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Aim2 Deficiency Stimulates the Expression of IFN-Inducible Ifi202, a Lupus Susceptibility Murine Gene within the Nba2 Autoimmune Susceptibility Locus

12 July 2018

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Cytokine-dependent but acquired immunity-independent arthritis caused by DNA escaped from degradation

12 July 2018

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The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

12 July 2018

1 reference

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STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

12 July 2018

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An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482750

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482750

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482750

HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482750

Recognition of microorganisms and activation of the immune response

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482750

Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA

12 July 2018

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Requirement of DNase II for definitive erythropoiesis in the mouse fetal liver

12 July 2018

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Inflammatory cytokines break down intrinsic immunological tolerance of human primary keratinocytes to cytosolic DNA.

12 July 2018

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Immunoblotting for active caspase-1.

25 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482750

Maternally expressed PGK-Cre transgene as a tool for early and uniform activation of the Cre site-specific recombinase

25 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482750

Aicardi–Goutières syndrome

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0131702

Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0131702

10.1371/JOURNAL.PONE.0131702

21 January 2018

Identifiers

DOI

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9 August 2017

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9 August 2017

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