Does diabetes protect or provoke Alzheimer's disease? Insights into the pathobiology and future treatment of Alzheimer's disease (Q35618911)

9 August 2017

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title

Does diabetes protect or provoke Alzheimer's disease? Insights into the pathobiology and future treatment of Alzheimer's disease (English)

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9 August 2017

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Hillel Grossman

1

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9 August 2017

publication date

1 November 2003

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9 August 2017

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9 August 2017

volume

8

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9 August 2017

issue

11

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9 August 2017

page(s)

815-823

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Purified recombinant insulin-degrading enzyme degrades amyloid beta-protein but does not promote its oligomerization

9 August 2017

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Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme

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Insulin-degrading enzyme rapidly removes the beta-amyloid precursor protein intracellular domain (AICD)

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Differential effects of proteases involved in intracellular degradation of amyloid beta-protein between detergent-soluble and -insoluble pools in CHO-695 cells

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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7 January 2021

Heritability of plasma amyloid beta in typical late-onset Alzheimer's disease pedigrees

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7 January 2021

Insulin-degrading enzyme in the Alzheimer's disease brain: prominent localization in neurons and senile plaques

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7 January 2021

Turnover of Amyloid β-Protein in Mouse Brain and Acute Reduction of Its Level by Phorbol Ester

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7 January 2021

Inflammatory mechanisms in Alzheimer's disease: inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists.

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7 January 2021

Regulation of multicatalytic enzyme activity by insulin and the insulin-degrading enzyme

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7 January 2021

Has familial aggregation in Alzheimer's disease been overestimated?

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7 January 2021

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7 January 2021

Advanced glycation end products contribute to amyloidosis in Alzheimer disease

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7 January 2021

Effect of metformin on advanced glycation endproduct formation and peripheral nerve function in streptozotocin-induced diabetic rats

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7 January 2021

Brain insulin: regulation, mechanisms of action and functions

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7 January 2021

Changes in blood glucose and insulin secretion in patients with senile dementia of Alzheimer type

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7 January 2021

Evidence for genetic linkage of Alzheimer's disease to chromosome 10q

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7 January 2021

Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation

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7 January 2021

Insulysin hydrolyzes amyloid beta peptides to products that are neither neurotoxic nor deposit on amyloid plaques.

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7 January 2021

Advanced glycation endproducts in ageing and Alzheimer's disease

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7 January 2021

Diabetes and change in cognitive function

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7 January 2021

Effects of hyperglycemia on memory and hormone levels in dementia of the Alzheimer type: a longitudinal study

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7 January 2021

10.1017/S1092852900019258

Identifiers

DOI

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9 August 2017

1 reference