Cdk5 Modulation of mitogen-activated protein kinase signaling regulates neuronal survival (Q35613392)

9 August 2017

title

Cdk5 Modulation of mitogen-activated protein kinase signaling regulates neuronal survival (English)

1 reference

9 August 2017

Ya-Li Zheng

1

1 reference

9 August 2017

Bing-Sheng Li

2

1 reference

9 August 2017

Jyotshna Kanungo

3

1 reference

9 August 2017

Sashi Kesavapany

4

1 reference

9 August 2017

Niranjana Amin

5

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9 August 2017

Philip Grant

6

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9 August 2017

Harish C Pant

7

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9 August 2017

publication date

15 November 2006

1 reference

Molecular Biology of the Cell

9 August 2017

published in

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9 August 2017

volume

18

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9 August 2017

issue

2

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9 August 2017

page(s)

404-413

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describes a project that uses

9 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1783783/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Emerging role for ERK as a key regulator of neuronal apoptosis

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Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

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Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor

27 July 2018

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27 July 2018

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Synaptic roles of Cdk5: implications in higher cognitive functions and neurodegenerative diseases

25 September 2018

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25 September 2018

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p35/cyclin-dependent kinase 5 phosphorylation of ras guanine nucleotide releasing factor 2 (RasGRF2) mediates Rac-dependent Extracellular Signal-regulated kinase 1/2 activity, altering RasGRF2 and microtubule-associated protein 1b distribution in ne

25 September 2018

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Decreased cyclin-dependent kinase 5 (cdk5) activity is accompanied by redistribution of cdk5 and cytoskeletal proteins and increased cytoskeletal protein phosphorylation in p35 null mice.

25 September 2018

1 reference

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Cyclin-dependent kinase-5 is involved in neuregulin-dependent activation of phosphatidylinositol 3-kinase and Akt activity mediating neuronal survival

25 September 2018

1 reference

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Growth differentiation factor-15 prevents low potassium-induced cell death of cerebellar granule neurons by differential regulation of Akt and ERK pathways

25 September 2018

1 reference

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ERK signaling: duration, duration, duration.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783783

A peptide derived from cyclin-dependent kinase activator (p35) specifically inhibits Cdk5 activity and phosphorylation of tau protein in transfected cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783783

Cdk5/p35 regulates neurotransmitter release through phosphorylation and downregulation of P/Q-type voltage-dependent calcium channel activity.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783783

ERK induces p35, a neuron-specific activator of Cdk5, through induction of Egr1.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783783

Mitogen-activated protein kinases (Erk1,2) phosphorylate Lys-Ser-Pro (KSP) repeats in neurofilament proteins NF-H and NF-M.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783783

Differential expression of MEK1 and MEK2 during mouse development

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783783

Phosphorylation of MEK1 by cdk5/p35 down-regulates the mitogen-activated protein kinase pathway

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783783

Neuronal cyclin-dependent kinase 5 activity is critical for survival.

15 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783783

Tau protein is hyperphosphorylated in a site-specific manner in apoptotic neuronal PC12 cells

15 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783783

The beta-PDGF receptor induces neuronal differentiation of PC12 cells

15 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783783

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

15 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17108320

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17108320

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1091/MBC.E06-09-0851

1 reference

9 August 2017

1 reference

9 August 2017

1 reference