An insight into the genetic pathway of adenocarcinoma of the small intestine (Q35594366)

9 August 2017

title

An insight into the genetic pathway of adenocarcinoma of the small intestine (English)

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9 August 2017

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11

W F Bodmer

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9 August 2017

J M D Wheeler

1

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9 August 2017

B F Warren

2

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9 August 2017

N J McC Mortensen

3

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9 August 2017

H C Kim

4

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9 August 2017

S C Biddolph

5

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9 August 2017

G Elia

6

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9 August 2017

N E Beck

7

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9 August 2017

G T Williams

8

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9 August 2017

N A Shepherd

9

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9 August 2017

A C Bateman

10

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9 August 2017

language of work or name

English

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publication date

1 February 2002

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9 August 2017

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9 August 2017

volume

50

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9 August 2017

issue

2

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9 August 2017

page(s)

218-223

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Hypermethylation of the promoter region of the E-cadherin gene (CDH1) in sporadic and ulcerative colitis associated colorectal cancer

9 August 2017

cites work

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27 July 2018

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Mechanisms of inactivation of mismatch repair genes in human colorectal cancer cell lines: the predominant role of hMLH1.

27 July 2018

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Genetic pathways in colorectal and other cancers

27 July 2018

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Mutated epithelial cadherin is associated with increased tumorigenicity and loss of adhesion and of responsiveness to the motogenic trefoil factor 2 in colon carcinoma cells

27 July 2018

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Causes and consequences of microsatellite instability in endometrial carcinoma.

27 July 2018

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Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers.

27 July 2018

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Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

27 July 2018

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Loss of beta-catenin regulation by the APC tumor suppressor protein correlates with loss of structure due to common somatic mutations of the gene

27 July 2018

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27 July 2018

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Molecular genetics of small bowel cancer

27 July 2018

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Beta-catenin mutations in cell lines established from human colorectal cancers

27 July 2018

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The interactions of APC, E-cadherin and beta-catenin in tumour development and progression

27 July 2018

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Genetic alterations in sporadic and Crohn's-associated adenocarcinomas of the small intestine.

27 July 2018

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Allele loss, replication errors and loss of expression of E-cadherin in colorectal cancers

27 July 2018

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Expression of E-cadherin-associated molecules (alpha-, beta-, and gamma-catenins and p120) in colorectal polyps.

27 July 2018

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An overview of adenocarcinoma of the small intestine

27 July 2018

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The presence of K-12 ras mutations in duodenal adenocarcinomas and the absence of ras mutations in other small bowel adenocarcinomas and carcinoid tumors

27 July 2018

1 reference

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Hypermethylation of the APC (adenomatous polyposis coli) gene promoter region in human colorectal carcinoma.

27 July 2018

1 reference

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Small bowel cancer. Clinical and pathologic features.

27 July 2018

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Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

27 July 2018

1 reference

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Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines

27 July 2018

1 reference

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Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

27 July 2018

1 reference

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The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773117

Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773117

Mutation of a mutL homolog in hereditary colon cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773117

Mutations of the APC (adenomatous polyposis coli) gene

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773117

Mutations of two PMS homologues in hereditary nonpolyposis colon cancer

27 July 2018

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27 July 2018

p53 and human cancers.

1 reference

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Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein

27 July 2018

1 reference

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Mutations of GTBP in genetically unstable cells

27 July 2018

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Why are small-bowel tumours so rare?

27 July 2018

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A genetic model for colorectal tumorigenesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773117

Investigations on the significance of the adenoma-carcinoma sequence in the small bowel

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773117

Epidemiology of adenocarcinomas of the small intestine: is bile a small bowel carcinogen?

27 July 2018

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Identification and characterization of the familial adenomatous polyposis coli gene

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773117

APC mutations occur early during colorectal tumorigenesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773117

A possible explanation for the differential cancer incidence in the intestine, based on distribution of the cytotoxic effects of carcinogens in the murine large bowel

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773117

Frequent somatic mutations of the APC gene in human pancreatic cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773117

Somatic mutation of the APC gene in gastric cancer: frequent mutations in very well differentiated adenocarcinoma and signet-ring cell carcinoma

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773117

The APC gene, responsible for familial adenomatous polyposis, is mutated in human gastric cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773117

Mutations of the human E-cadherin (CDH1) gene

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773117

Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773117

Determination of the replication error phenotype in human tumors without the requirement for matching normal DNA by analysis of mononucleotide repeat microsatellites

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773117

Germ-line mutation of the hMSH6/GTBP gene in an atypical hereditary nonpolyposis colorectal cancer kindred

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773117

The somatic evolution of cancer. The Harveian Oration of 1996.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773117

Mutations of the Ki-ras, p53 and APC genes in adenocarcinomas of the human small intestine.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773117

The association between cancers of the small and large bowel

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773117

Frequent genetic instability in small intestinal carcinomas.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773117

Somatic mutations of the adenomatous polyposis coli gene in gastroduodenal tumors from patients with familial adenomatous polyposis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773117

Hypermethylation of the hMLH1 gene promoter in human gastric cancers with microsatellite instability

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1773117

Primary malignant tumors of the small bowel

26 September 2018

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12 December 2020

Primary small bowel malignancies

1 reference

12 December 2020

Microsatellite instability and hereditary non-polyposis colon cancer

1 reference

12 December 2020

E-cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas

1 reference

12 December 2020

Frequent K-ras mutations in small bowel adenocarcinomas

1 reference

12 December 2020

Involvement of calpain in integrin-mediated signal transduction

1 reference

12 December 2020

MLH1 promoter methylation and gene silencing is the primary cause of microsatellite instability in sporadic endometrial cancers

1 reference

12 December 2020

The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC)

1 reference

12 December 2020

Extracolonic cancer in hereditary nonpolyposis colorectal cancer

1 reference

12 December 2020

Mutations predisposing to hereditary nonpolyposis colorectal cancer: Database and results of a collaborative study. The International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer

1 reference

12 December 2020

hMLH1 promoter methylation and lack of hMLH1 expression in sporadic gastric carcinomas with high-frequency microsatellite instability

1 reference

12 December 2020

Identifiers

DOI

10.1136/GUT.50.2.218

1 reference

9 August 2017

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9 August 2017

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