Molecular recognition at adenine nucleotide (P2) receptors in platelets. (Q35580443)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15852224%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

review article

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title

Molecular recognition at adenine nucleotide (P2) receptors in platelets (English)

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11 January 2020

1

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11 January 2020

Stefano Costanzi

5

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11 January 2020

author name string

Liaman Mamedova

2

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11 January 2020

Bhalchandra V Joshi

3

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11 January 2020

Pedro Besada

4

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11 January 2020

publication date

1 April 2005

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Seminars in Thrombosis and Hemostasis

11 January 2020

published in

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11 January 2020

volume

31

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11 January 2020

issue

2

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11 January 2020

page(s)

205-216

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Evidence for the Recognition of Non-Nucleotide Antagonists Within the Transmembrane Domains of the Human P2Y(1) Receptor

11 January 2020

cites work

1 reference

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Activity of Novel Adenine Nucleotide Derivatives as Agonists and Antagonists at Recombinant Rat P2X Receptors

12 July 2018

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Architecture of P2Y nucleotide receptors: structural comparison based on sequence analysis, mutagenesis, and homology modeling.

12 July 2018

1 reference

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Antiaggregatory activity in human platelets of potent antagonists of the P2Y 1 receptor.

12 July 2018

1 reference

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Induction of novel agonist selectivity for the ADP-activated P2Y1 receptor versus the ADP-activated P2Y12 and P2Y13 receptors by conformational constraint of an ADP analog.

12 July 2018

1 reference

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2,2'-Pyridylisatogen tosylate antagonizes P2Y1 receptor signaling without affecting nucleotide binding

12 July 2018

1 reference

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Diisothiocyanate derivatives as potent, insurmountable antagonists of P2Y6 nucleotide receptors.

12 July 2018

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Molecular structure of P2X receptors

12 July 2018

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Structure-activity relationships of analogues of NF449 confirm NF449 as the most potent and selective known P2X1 receptor antagonist

12 July 2018

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2-Substitution of Adenine Nucleotide Analogues Containing a Bicyclo[3.1.0]hexane Ring System Locked in a Northern Conformation: Enhanced Potency as P2Y1 Receptor Antagonists

12 July 2018

1 reference

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ADP Receptors-Targets for Developing Antithrombotic Agents

12 July 2018

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A role of the fast ATP-gated P2X1 cation channel in thrombosis of small arteries in vivo

12 July 2018

1 reference

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Both the ADP receptors P2Y1 and P2Y12, play a role in controlling shape change in human platelets

12 July 2018

1 reference

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Interaction between cysteines introduced into each transmembrane domain of the rat P2X2 receptor

12 July 2018

1 reference

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Acyclic analogues of adenosine bisphosphates as P2Y receptor antagonists: phosphate substitution leads to multiple pathways of inhibition of platelet aggregation.

12 July 2018

1 reference

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Adenosine 5'-O-(1-boranotriphosphate) derivatives as novel P2Y(1) receptor agonists.

12 July 2018

1 reference

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Quantitation of the P2Y(1) receptor with a high affinity radiolabeled antagonist

12 July 2018

1 reference

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Structure-activity relationships of suramin and pyridoxal-5'-phosphate derivatives as P2 receptor antagonists

12 July 2018

1 reference

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Purine and pyrimidine (P2) receptors as drug targets

12 July 2018

1 reference

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Adenine nucleotide analogues locked in a Northern methanocarba conformation: enhanced stability and potency as P2Y(1) receptor agonists

12 July 2018

1 reference

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2-Chloro N(6)-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate is a selective high affinity P2Y(1) receptor antagonist

12 July 2018

1 reference

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Heteromultimeric P2X(1/2) receptors show a novel sensitivity to extracellular pH

12 July 2018

1 reference

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Methanocarba modification of uracil and adenine nucleotides: high potency of Northern ring conformation at P2Y1, P2Y2, P2Y4, and P2Y11 but not P2Y6 receptors

12 July 2018

1 reference

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Structure-activity relationships of pyridoxal phosphate derivatives as potent and selective antagonists of P2X1 receptors

12 July 2018

1 reference

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Molecular identification and characterization of the platelet ADP receptor targeted by thienopyridine antithrombotic drugs

12 July 2018

1 reference

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Identification of the platelet ADP receptor targeted by antithrombotic drugs

12 July 2018

1 reference

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Inhibition of platelet function by administration of MRS2179, a P2Y1 receptor antagonist

12 July 2018

1 reference

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Antiplatelet action of R-99224, an active metabolite of a novel thienopyridine-type G(i)-linked P2T antagonist, CS-747

12 July 2018

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Crystal structure of rhodopsin: A G protein-coupled receptor

12 July 2018

1 reference

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Functional properties of heteromeric P2X(1/5) receptors expressed in HEK cells and excitatory junction potentials in guinea-pig submucosal arterioles

12 July 2018

1 reference

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Pharmacological characterization of the human P2Y11 receptor

12 July 2018

1 reference

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Diinosine pentaphosphate (IP5I) is a potent antagonist at recombinant rat P2X1 receptors.

12 July 2018

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The role of amino acids in extracellular loops of the human P2Y1 receptor in surface expression and activation processes.

12 July 2018

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Agonist action of adenosine triphosphates at the human P2Y1 receptor

12 July 2018

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P2X1 and P2X3 receptors form stable trimers: a novel structural motif of ligand-gated ion channels

12 July 2018

1 reference

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Human P2Y1 receptor: molecular modeling and site-directed mutagenesis as tools to identify agonist and antagonist recognition sites.

12 July 2018

1 reference

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A Mutational Analysis of Residues Essential for Ligand Recognition at the Human P2Y1Receptor

12 July 2018

1 reference

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Identification of competitive antagonists of the P2Y1 receptor.

12 July 2018

1 reference

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Potentiation by 2,2'-pyridylisatogen tosylate of ATP-responses at a recombinant P2Y1 purinoceptor

12 July 2018

1 reference

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Identification of potent P2Y-purinoceptor agonists that are derivatives of adenosine 5'-monophosphate

12 July 2018

1 reference

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PPADS and suramin as antagonists at cloned P2Y- and P2U-purinoceptors

12 July 2018

1 reference

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Identification of potent, selective P2Y-purinoceptor agonists: structure-activity relationships for 2-thioether derivatives of adenosine 5'-triphosphate

12 July 2018

1 reference

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Analogues of diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) as potential anti-platelet-aggregation agents

12 July 2018

1 reference

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Synthesis and biological activity of 2-alkylated deoxyadenosine bisphosphate derivatives as P2Y(1) receptor antagonists

12 July 2018

1 reference

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Purification and Functional Reconstitution of the Human P2Y12Receptor

26 September 2018

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Evaluation of reactive blue 2 derivatives as selective antagonists for P2Y receptors

26 September 2018

1 reference

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Differential involvement of the P2Y1 and P2Y12 receptors in platelet procoagulant activity

26 September 2018

1 reference

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YM-254890, a novel platelet aggregation inhibitor produced by Chromobacterium sp. QS3666.

26 September 2018

1 reference

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Pharmacological characterization of the human P2Y13 receptor

26 September 2018

1 reference

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A general approach toward the synthesis of C-nucleoside pyrazolo[1,5-a]-1,3,5-triazines and their 3',5'-bisphosphate C-nucleotide analogues as the first reported in vivo stable P2Y(1)-receptor antagonists

26 September 2018

1 reference

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Conserved negatively charged residues are not required for ATP action at P2X(1) receptors

26 September 2018

1 reference

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Selective agonism of group I P2X receptors by dinucleotides dependent on a single adenine moiety.

26 September 2018

1 reference

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Acyclic and cyclopropyl analogues of adenosine bisphosphate antagonists of the P2Y1 receptor: structure-activity relationships and receptor docking

26 September 2018

1 reference

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NF449: a subnanomolar potency antagonist at recombinant rat P2X1 receptors

26 September 2018

1 reference

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Novel tricyclic benzothiazolo[2,3-c]thiadiazine antagonists of the platelet ADP receptor (P2Y(12)).

26 September 2018

1 reference

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The novel heteromeric bivalent ligand SB9 potently antagonizes P2Y(1) receptor-mediated responses

26 September 2018

1 reference

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Pharmacological characterization of recombinant human and rat P2X receptor subtypes

26 September 2018

1 reference

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2-thioether 5'-O-(1-thiotriphosphate)adenosine derivatives as new insulin secretagogues acting through P2Y-Receptors

26 September 2018

1 reference

12 December 2020

Synthesis, Biological Activity, and Molecular Modeling of Ribose-Modified Deoxyadenosine Bisphosphate Analogues as P2Y1Receptor Ligands

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12 December 2020

Identification and biological activity of the active metabolite of clopidogrel

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12 December 2020

Actions of a Series of PPADS Analogs at P2X1 and P2X3 Receptors

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12 December 2020

Antagonists of the platelet P2T receptor: a novel approach to antithrombotic therapy

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12 December 2020

Identifiers

DOI

10.1055/S-2005-869526

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15852224%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15852224%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

PubMed publication ID

15852224

1 reference