Mutations in the connection domain of HIV-1 reverse transcriptase increase 3'-azido-3'-deoxythymidine resistance (Q35576015)

8 August 2017

title

Mutations in the connection domain of HIV-1 reverse transcriptase increase 3'-azido-3'-deoxythymidine resistance (English)

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8 August 2017

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4

Frank Maldarelli

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8 August 2017

6

John M Coffin

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8 August 2017

3

Sarah Palmer

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8 August 2017

Galina N Nikolenko

1

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8 August 2017

Krista A Delviks-Frankenberry

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2

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8 August 2017

Matthew J Fivash

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5

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8 August 2017

Vinay K Pathak

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7

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8 August 2017

language of work or name

English

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publication date

19 December 2006

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Proceedings of the National Academy of Sciences of the United States of America

8 August 2017

published in

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8 August 2017

volume

104

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8 August 2017

issue

1

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8 August 2017

page(s)

317-322

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Nucleoside and nucleotide inhibitors of HIV-1 replication.

8 August 2017

cites work

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The L74V mutation in human immunodeficiency virus type 1 reverse transcriptase counteracts enhanced excision of zidovudine monophosphate associated with thymidine analog resistance mutations

27 July 2018

1 reference

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Mechanism for nucleoside analog-mediated abrogation of HIV-1 replication: balance between RNase H activity and nucleotide excision

27 July 2018

1 reference

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Multiple, linked human immunodeficiency virus type 1 drug resistance mutations in treatment-experienced patients are missed by standard genotype analysis

27 July 2018

1 reference

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Mutations in the RNase H primer grip domain of murine leukemia virus reverse transcriptase decrease efficiency and accuracy of plus-strand DNA transfer

27 July 2018

1 reference

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Mutation of amino acids in the connection domain of human immunodeficiency virus type 1 reverse transcriptase that contact the template-primer affects RNase H activity.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1765458

The M184V mutation reduces the selective excision of zidovudine 5'-monophosphate (AZTMP) by the reverse transcriptase of human immunodeficiency virus type 1

27 July 2018

1 reference

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Structured intermittent treatment for HIV disease: Necessary concession or premature compromise?

27 July 2018

1 reference

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Increased ability for selection of zidovudine resistance in a distinct class of wild-type HIV-1 from drug-naive persons

27 July 2018

1 reference

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Dynamic copy choice: steady state between murine leukemia virus polymerase and polymerase-dependent RNase H activity determines frequency of in vivo template switching

27 July 2018

1 reference

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Structural determinants of murine leukemia virus reverse transcriptase that affect the frequency of template switching

27 July 2018

1 reference

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The M184V mutation in the reverse transcriptase of human immunodeficiency virus type 1 impairs rescue of chain-terminated DNA synthesis

27 July 2018

1 reference

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A novel phenotypic drug susceptibility assay for human immunodeficiency virus type 1

27 July 2018

1 reference

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Mutation patterns of the reverse transcriptase and protease genes in human immunodeficiency virus type 1-infected patients undergoing combination therapy: survey of 787 sequences

27 July 2018

1 reference

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A novel polymorphism at codon 333 of human immunodeficiency virus type 1 reverse transcriptase can facilitate dual resistance to zidovudine and L-2',3'-dideoxy-3'-thiacytidine

27 July 2018

1 reference

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Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

27 July 2018

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Antiretroviral drug resistance mutations in human immunodeficiency virus type 1 reverse transcriptase increase template-switching frequency

27 July 2018

1 reference

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Patterns of resistance mutations selected by treatment of human immunodeficiency virus type 1 infection with zidovudine, didanosine, and nevirapine

21 January 2018

1 reference

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Thymidine analogue reverse transcriptase inhibitors resistance mutations profiles and association to other nucleoside reverse transcriptase inhibitors resistance mutations observed in the context of virological failure

21 January 2018

1 reference

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Impaired rescue of chain-terminated DNA synthesis associated with the L74V mutation in human immunodeficiency virus type 1 reverse transcriptase

21 January 2018

1 reference

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RNase H activity is required for high-frequency repeat deletion during Moloney murine leukemia virus replication

21 January 2018

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Altering the RNase H primer grip of human immunodeficiency virus reverse transcriptase modifies cleavage specificity

21 January 2018

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A general method for the generation of high-titer, pantropic retroviral vectors: highly efficient infection of primary hepatocytes

21 January 2018

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Role of matrix in an early postentry step in the human immunodeficiency virus type 1 life cycle

21 January 2018

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26 September 2018

Identifiers

DOI

10.1073/PNAS.0609642104

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8 August 2017

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8 August 2017

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