Function and regulation of the CD95 (APO-1/Fas) ligand in the immune system (Q35561571)

8 August 2017

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title

Function and regulation of the CD95 (APO-1/Fas) ligand in the immune system (English)

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8 August 2017

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https://api.crossref.org/works/10.1016/S1044-5323(03)00030-7

22 March 2024

author name string

Min Li-Weber

1

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8 August 2017

Peter H. Krammer

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14563113

22 March 2024

language of work or name

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1 June 2003

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full work available at URL

8 August 2017

https://api.elsevier.com/content/article/PII:S1044532303000307?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/S1044-5323(03)00030-7

https://api.elsevier.com/content/article/PII:S1044532303000307?httpAccept=text/plain

22 March 2024

1 reference

https://api.crossref.org/works/10.1016/S1044-5323(03)00030-7

22 March 2024

published in

Seminars in Immunology

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8 August 2017

volume

15

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8 August 2017

issue

3

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8 August 2017

page(s)

145-157

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CD95's deadly mission in the immune system

8 August 2017

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Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease

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Alterations of Fas (Apo-1/CD95) gene in cutaneous malignant melanoma

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Alterations of Fas (Apo-1/CD95) gene in non-small cell lung cancer.

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Somatic mutations of Fas (Apo-1/CD95) gene in cutaneous squamous cell carcinoma arising from a burn scar

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Somatic mutations in the death domain of the Fas (Apo-1/CD95) gene in gastric cancer.

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Fas gene mutations in prostatic intraepithelial neoplasia and concurrent carcinoma: analysis of laser capture microdissected specimens

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7 January 2021

Loss of Fas (CD95/APO-1) regulatory function is an important step in early MALT-type lymphoma development

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Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

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Human germinal center B cells express the apoptosis-inducing genes Fas, c-myc, P53, and Bax but not the survival gene bcl-2

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Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals.

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HIV-1 upregulates Fas ligand expression in CD4+ T cells in vitro and in vivo: association with Fas-mediated apoptosis and modulation by aurintricarboxylic acid

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Membrane and soluble forms of Fas (CD95) and Fas ligand in peripheral blood mononuclear cells and in plasma from human immunodeficiency virus-infected persons.

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7 January 2021

Correlation of loss of CD4 T cells with plasma levels of both soluble form Fas (CD95) Fas ligand (FasL) in HIV-infected infants

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7 January 2021

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

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7 January 2021

Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape

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7 January 2021

The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand

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7 January 2021

Tumor expression of Fas ligand (CD95L) and the consequences

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7 January 2021

Cutting Edge: The Tumor Counterattack Hypothesis Revisited: Colon Cancer Cells Do Not Induce T Cell Apoptosis Via the Fas (CD95, APO-1) Pathway

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7 January 2021

Expression of Fas ligand in liver metastases of human colonic adenocarcinomas

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Fas receptor counterattack against tumor-infiltrating lymphocytes in vivo as a mechanism of immune escape in gastric carcinoma

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Synergistic action of protein kinase C θ and calcineurin is sufficient for Fas ligand expression and induction of a crmA-sensitive apoptosis pathway in Jurkat T cells

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7 January 2021

NF-kappa B-dependent Fas ligand expression

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7 January 2021

Models of T cell anergy: is there a common molecular mechanism?

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7 January 2021

T cell signaling: a decision of life and death

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7 January 2021

The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses

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7 January 2021

Protein kinase C(theta) in T cell activation

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7 January 2021

Up-regulation of c-FLIPshort and reduction of activation-induced cell death in CD28-costimulated human T cells.

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7 January 2021

The regulation of CD95 (Fas) ligand expression in primary T cells: induction of promoter activation in CD95LP-Luc transgenic mice

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7 January 2021

The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance

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7 January 2021

A novel AP-1 element in the CD95 ligand promoter is required for induction of apoptosis in hepatocellular carcinoma cells upon treatment with anticancer drugs

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7 January 2021

DNA damage signals induction of fas ligand in tumor cells.

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7 January 2021

Oncogenic transformation potentiates apoptosis, S-phase arrest and stress-kinase activation by etoposide

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7 January 2021

DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1.

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7 January 2021

Stress-induced Fas ligand expression in T cells is mediated through a MEK kinase 1-regulated response element in the Fas ligand promoter

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7 January 2021

Regulation of CD95 (Apo-1/Fas) ligand and receptor expression in human embryonal carcinoma cells by interferon gamma and all-trans retinoic acid

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7 January 2021

Regulation of CD95 (Apo-1/Fas) ligand and receptor expression in squamous-cell carcinoma by interferon-gamma and cisplatin

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7 January 2021

Induction of apoptosis by IFNγ in human neuroblastoma cell lines through the CD95/CD95L autocrine circuit

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7 January 2021

Interferon-gamma induces apoptosis and augments the expression of Fas and Fas ligand by microglia in vitro

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7 January 2021

IRF family of transcription factors as regulators of host defense

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7 January 2021

The anti-inflammatory sesquiterpene lactone parthenolide suppresses CD95-mediated activation-induced-cell-death in T-cells

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7 January 2021

Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

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7 January 2021

Viral IFN-regulatory factors inhibit activation-induced cell death via two positive regulatory IFN-regulatory factor 1-dependent domains in the CD95 ligand promoter

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7 January 2021

A 'non-canonical' DNA-binding element mediates the response of the Fas-ligand promoter to c-Myc.

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7 January 2021

Two NFAT Transcription Factor Binding Sites Participate in the Regulation of CD95 (Fas) Ligand Expression in Activated Human T Cells

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T cell activation-induced and HIV tat-enhanced CD95(APO-1/Fas) ligand transcription involves NF-kappaB

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7 January 2021

Cyclosporin A-sensitive transcription factor Egr-3 regulates Fas ligand expression

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7 January 2021

Role of Egr-2 in up-regulation of Fas ligand in normal T cells and aberrant double-negative lpr and gld T cells

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7 January 2021

Novel Egr/NF-AT composite sites mediate activation of the CD95 (APO-1/Fas) ligand promoter in response to T cell stimulation

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7 January 2021

The IFN regulatory factor family participates in regulation of Fas ligand gene expression in T cells

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7 January 2021

Transcriptional Regulation of the Human FasL Promoter-Enhancer Region

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7 January 2021

Regulation of fas-ligand expression during activation-induced cell death in T lymphocytes via nuclear factor kappaB.

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7 January 2021

Transcription factors of the NFAT family: regulation and function

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A regulatory element in the CD95 (APO-1/Fas) ligand promoter is essential for responsiveness to TCR-mediated activation

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7 January 2021

The EGR family of transcription-regulatory factors: progress at the interface of molecular and systems neuroscience.

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7 January 2021

Sequential involvement of NFAT and Egr transcription factors in FasL regulation

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7 January 2021

Differential expression of Fas ligand in Th1 and Th2 cells is regulated by early growth response gene and NF-AT family members

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7 January 2021

Differential ability of Th1 and Th2 T cells to express Fas ligand and to undergo activation-induced cell death

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7 January 2021

The essential role of phorbol ester-sensitive protein kinase C isoforms in activation-induced cell death of Th1 cells

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7 January 2021

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

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7 January 2021

Protein kinase C-theta;: signaling from the center of the T-cell synapse

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Proteasome regulation of activation-induced T cell death

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Proteasome regulation of Fas ligand cytotoxicity

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7 January 2021

Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120.

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7 January 2021

Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein

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7 January 2021

HIV Tat binds Egr proteins and enhances Egr-dependent transactivation of the Fas ligand promoter

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7 January 2021

The Myc/Max/Mad network and the transcriptional control of cell behavior

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Signaling networks that link cell proliferation and cell fate

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7 January 2021

Fungal metabolite FR901228 inhibits c-Myc and Fas ligand expression

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Transforming growth factor beta1 inhibits Fas ligand expression and subsequent activation-induced cell death in T cells via downregulation of c-Myc

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7 January 2021

Expression of Fas ligand in activated T cells is regulated by c-Myc

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7 January 2021

Coactivators in transcription initiation: here are your orders.

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Nuclear hormone receptors in T lymphocytes

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Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77.

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7 January 2021

Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas

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7 January 2021

Nur77 transcription activity correlates with its apoptotic function in vivo

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A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection

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Apoptosis of nur77/N10-transgenic thymocytes involves the Fas/Fas ligand pathway

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7 January 2021

Ca(2+)-dependent gene expression mediated by MEF2 transcription factors.

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7 January 2021

Cabin1 represses MEF2-dependent Nur77 expression and T cell apoptosis by controlling association of histone deacetylases and acetylases with MEF2

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7 January 2021

Unimpaired thymic and peripheral T cell death in mice lacking the nuclear receptor NGFI-B (Nur77)

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7 January 2021

Constitutive Fas ligand gene transcription in Sertoli cells is regulated by Sp1.

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7 January 2021

Sp1 phosphorylation regulates apoptosis via extracellular FasL-Fas engagement

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7 January 2021

FasL promoter activation by IL-2 through SP1 and NFAT but not Egr-2 and Egr-3

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7 January 2021

Sp1 is the major fasl gene activator in abnormal CD4(-)CD8(-)B220(+) T cells of lpr and gld mice

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7 January 2021

Regulation of Fas ligand expression and cell death by apoptosis-linked gene 4

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7 January 2021

RORgamma t, a novel isoform of an orphan receptor, negatively regulates Fas ligand expression and IL-2 production in T cells

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7 January 2021

Cutting edge: the class II transactivator prevents activation-induced cell death by inhibiting Fas ligand gene expression

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7 January 2021

Aberrant expression of Fas ligand in mice deficient for the MHC class II transactivator

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7 January 2021

Molecular mechanisms of activated T cell death in vivo

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7 January 2021

Bcl-2-mediated drug resistance: inhibition of apoptosis by blocking nuclear factor of activated T lymphocytes (NFAT)-induced Fas ligand transcription

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7 January 2021

Intracellular oxidation/reduction status in the regulation of transcription factors NF-kappaB and AP-1.

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7 January 2021

NF-kappaB as a primary regulator of the stress response

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7 January 2021

Oxidative stress and nuclear factor-kappaB activation: a reassessment of the evidence in the light of recent discoveries.

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7 January 2021

Role of redox potential and reactive oxygen species in stress signaling

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7 January 2021

Vitamin E inhibits CD95 ligand expression and protects T cells from activation-induced cell death

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7 January 2021

The role of metabolism in the antioxidant function of vitamin E.

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7 January 2021

22 Vitamin E status and immune function

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Vitamin E and immunity

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7 January 2021

Decreased antioxidant defence in individuals infected by the human immunodeficiency virus

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7 January 2021

Antioxidant status and lipid peroxidation in patients infected with HIV.

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7 January 2021

Fas and activation-induced Fas ligand mediate apoptosis of T cell hybridomas: inhibition of Fas ligand expression by retinoic acid and glucocorticoids

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900030-7

7 January 2021

9-cis retinoic acid inhibition of activation-induced apoptosis is mediated via regulation of fas ligand and requires retinoic acid receptor and retinoid X receptor activation

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900030-7

7 January 2021

Retinoic acid inhibition of ex vivo human immunodeficiency virus-associated apoptosis of peripheral blood cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900030-7

7 January 2021

All-trans retinoic acid inhibition of anti-CD3-induced T cell apoptosis in human immunodeficiency virus infection mostly concerns CD4 T lymphocytes and is mediated via regulation of CD95 ligand expression

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900030-7

7 January 2021

Repression of FasL expression by retinoic acid involves a novel mechanism of inhibition of transactivation function of the nuclear factors of activated T-cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900030-7

7 January 2021

Selective upregulation of fibroblast Fas ligand expression, and prolongation of Fas/Fas ligand-mediated skin allograft survival, by retinoic acid: the skin as a retinoide-inducible immune privilege site

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900030-7

7 January 2021

Ethnopharmacology of Mexican asteraceae (Compositae).

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900030-7

7 January 2021

Ethnobotany and its role in drug development

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900030-7

7 January 2021

Sesquiterpene lactones specifically inhibit activation of NF-kappa B by preventing the degradation of I kappa B-alpha and I kappa B-beta

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900030-7

7 January 2021

Cysteine 38 in p65/NF-kappaB plays a crucial role in DNA binding inhibition by sesquiterpene lactones

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900030-7

7 January 2021

Glucocorticoids in T cell development and function*.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900030-7

7 January 2021

Glucocorticoids rescue CD4+ T lymphocytes from activation-induced apoptosis triggered by HIV-1: implications for pathogenesis and therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900030-7

7 January 2021

Glucocorticoids repress NF-kappaB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900030-7

7 January 2021

Antagonism between Nur77 and glucocorticoid receptor for control of transcription.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900030-7

7 January 2021

Inhibition of AP-1 by the glucocorticoid-inducible protein GILZ.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900030-7

7 January 2021

Transcriptional regulation by cyclic AMP-responsive factors

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900030-7

7 January 2021

Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit expression of Fas ligand in activated T lymphocytes by regulating c-Myc, NF-kappa B, NF-AT, and early growth factors 2/3.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900030-7

7 January 2021

Differential inducibility of the transcriptional repressor ICER and its role in modulation of Fas ligand expression in T and NK lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900030-7

7 January 2021

An unexpected role for FosB in activation-induced cell death of T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900030-7

7 January 2021

Alterations of Fas (APO-1/CD95) gene in transitional cell carcinomas of urinary bladder

21

1 reference

https://api.crossref.org/works/10.1016/S1044-5323(03)00030-7

Somatic mutations of the CD95 gene in Hodgkin and Reed-Sternberg cells

22 March 2024

32

1 reference

https://api.crossref.org/works/10.1016/S1044-5323(03)00030-7

22 March 2024

Identifiers

1 reference

8 August 2017

1 reference