Crossing the pain barrier: P2 receptors as targets for novel analgesics. (Q35545775)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14514872%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

review article

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title

Crossing the pain barrier: P2 receptors as targets for novel analgesics (English)

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19 December 2019

1

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19 December 2019

Edward G Rowan

series ordinal

4

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19 December 2019

author name string

T S Assis

series ordinal

2

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19 December 2019

A J Currie

series ordinal

3

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19 December 2019

language of work or name

English

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publication date

26 September 2003

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19 December 2019

published in

Journal of Physiology

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19 December 2019

volume

553

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19 December 2019

issue

Pt 3

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19 December 2019

page(s)

683-694

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Characterization of the UDP-glucose receptor (re-named here the P2Y14 receptor) adds diversity to the P2Y receptor family

19 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Acute nociception mediated by hindpaw P2X receptor activation in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

The effects of adenine nucleotides on cutaneous afferent nerve activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Identification of algogenic substances in human erythrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Observations on the algogenic actions of adenosine compounds on the human blister base preparation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

P2Y receptor-mediated inhibition of voltage-dependent Ca2+ channels in rat dorsal root ganglion neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

The expression of P2X3 purinoreceptors in sensory neurons: effects of axotomy and glial-derived neurotrophic factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Purinergic receptors: their role in nociception and primary afferent neurotransmission

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

A P2X purinoceptor expressed by a subset of sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Antagonism by aspirin and fenamates of bronchoconstriction and nociception induced by adenosine-5'-triphosphate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Distinct ATP receptors on pain-sensing and stretch-sensing neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Cell damage excites nociceptors through release of cytosolic ATP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Adenosine triphosphate-evoked vascular changes in human skin: Mechanism of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

P2X receptor-mediated excitation of nociceptive afferents in the normal and arthritic rat knee joint

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Antinociceptive effect of intrathecally administered P2-purinoceptor antagonists in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Immunoreactive localisation of P2Y1 receptors within the rat and human nodose ganglia and rat brainstem: comparison with [alpha 33P]deoxyadenosine 5'-triphosphate autoradiography

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Immunocytochemical localization of the vanilloid receptor 1 (VR1): relationship to neuropeptides, the P2X3 purinoceptor and IB4 binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Selective activation of nociceptors by P2X receptor agonists in normal and inflamed rat skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

The effects of inflammation and inflammatory mediators on nociceptive behaviour induced by ATP analogues in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

ATP in human skin elicits a dose-related pain response which is potentiated under conditions of hyperalgesia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

The liberation of adenosine triphosphate on antidromic stimulation of sensory nerves

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Analgesic profile of intrathecal P2X(3) antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

TNP-ATP, a potent P2X3 receptor antagonist, blocks acetic acid-induced abdominal constriction in mice: comparison with reference analgesics

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

ATP affects both axons and Schwann cells of unmyelinated C fibres

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Modulation of BzATP and formalin induced nociception: attenuation by the P2X receptor antagonist, TNP-ATP and enhancement by the P2X(3) allosteric modulator, cibacron blue

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Alteration of dorsal root ganglion P2X3 receptor expression and function following spinal nerve ligation in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Electrophysiological properties of P2X‐purinoceptors in rat superior cervical, nodose and guinea‐pig coeliac neurones

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Painful connection for ATP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Receptors for ATP in rat sensory neurones: the structure-function relationship for ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Ultrastructural localization of P2X3 receptors in rat sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

ATP and UTP excite sensory neurons and induce CREB phosphorylation through the metabotropic receptor, P2Y2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

A unified nomenclature for the superfamily of TRP cation channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

P2Y1 purinergic receptors in sensory neurons: contribution to touch-induced impulse generation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Distinct roles of P2X receptors in modulating glutamate release at different primary sensory synapses in rat spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Immunocytochemical localization of P2X3 purinoceptors in sensory neurons in naive rats and following neuropathic injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Analgesic effects of intrathecal administration of P2Y nucleotide receptor agonists UTP and UDP in normal and neuropathic pain model rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Inflammatory mediators potentiate ATP-gated channels through the P2X(3) subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Mechanism of action of ATP on canine pulmonary vagal C fibre nerve terminals

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Distribution of P2X1, P2X2, and P2X3 receptor subunits in rat primary afferents: relation to population markers and specific cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Pharmacological properties of P2X3-receptors present in neurones of the rat dorsal root ganglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Characterization of a P2X-purinoceptor in cultured neurones of the rat dorsal root ganglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Increase in intracellular Ca(2+) and calcitonin gene-related peptide release through metabotropic P2Y receptors in rat dorsal root ganglion neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Tackling pain at the source: new ideas about nociceptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Effects of spinally administered P2X receptor agonists and antagonists on the responses of dorsal horn neurones recorded in normal, carrageenan-inflamed and neuropathic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Potentiation of capsaicin receptor activity by metabotropic ATP receptors as a possible mechanism for ATP-evoked pain and hyperalgesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Characterization of purinoceptors mediating depolarization of rat isolated vagus nerve

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

The use of antagonists to characterize the receptors mediating depolarization of the rat isolated vagus nerve by alpha, beta-methylene adenosine 5'-triphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Downregulation of P2X3 receptor-dependent sensory functions in A/J inbred mouse strain

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Evidence for the involvement of spinal endogenous ATP and P2X receptors in nociceptive responses caused by formalin and capsaicin in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

TNP-ATP-resistant P2X ionic current on the central terminals and somata of rat primary sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Differential regulation of P2X(3) mRNA expression by peripheral nerve injury in intact and injured neurons in the rat sensory ganglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Cell type-specific ATP-activated responses in rat dorsal root ganglion neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Bradykinin and ATP accelerate Ca(2+) efflux from rat sensory neurons via protein kinase C and the plasma membrane Ca(2+) pump isoform 4

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Role of action potentials and calcium influx in ATP- and UDP-induced noradrenaline release from rat cultured sympathetic neurones

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Immunohistochemical study of the P2X2 and P2X3 receptor subunits in rat and monkey sensory neurons and their central terminals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Distinct neurochemical mechanisms are activated following administration of different P2X receptor agonists into the hindpaw of a rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

P2X receptor immunoreactivity in the rat cochlea, vestibular ganglion and cochlear nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Identification of gene expression profile of dorsal root ganglion in the rat peripheral axotomy model of neuropathic pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Changes in P2X receptor responses of sensory neurons from P2X3-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2003.049114

Possible involvement of P2Y2 metabotropic receptors in ATP-induced transient receptor potential vanilloid receptor 1-mediated thermal hypersensitivity.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2343624

Functional downregulation of P2X3 receptor subunit in rat sensory neurons reveals a significant role in chronic neuropathic and inflammatory pain.

15 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2343624

Peripheral inflammation sensitizes P2X receptor-mediated responses in rat dorsal root ganglion neurons.

15 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2343624

ATP P2X receptor-mediated enhancement of glutamate release and evoked EPSCs in dorsal horn neurons of the rat spinal cord.

15 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2343624

International union of pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunits

15 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2343624

Cloning OF P2X5 and P2X6 receptors and the distribution and properties of an extended family of ATP-gated ion channels

15 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2343624

The use of the writhing test in mice for screening different types of analgesics

15 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2343624

Distribution of P2X purinoceptor clusters on individual rat dorsal root ganglion cells

15 November 2018

1 reference

12 December 2020

P2X3 is expressed by DRG neurons that terminate in inner lamina II

1 reference

12 December 2020

Distinct ATP-activated currents in different types of neurons dissociated from rat dorsal root ganglion

1 reference

12 December 2020

Mechanical allodynia caused by intraplantar injection of P2X receptor agonist in rats: involvement of heteromeric P2X2/3 receptor signaling in capsaicin-insensitive primary afferent neurons

1 reference

12 December 2020

Analgesic activity of anticancer agent suramin

1 reference

12 December 2020

P2X3 receptor in injured human sensory neurons

1 reference

12 December 2020

ATP induces Ca2+ release from IP3-sensitive Ca2+ stores exclusively in large DRG neurones

1 reference

12 December 2020

P2X receptor-mediated ionic currents in dorsal root ganglion neurons

1 reference

12 December 2020

ATP-activated channels in rat and bullfrog sensory neurons: concentration dependence and kinetics

1 reference

12 December 2020

P2X purinoceptor-mediated excitation of trigeminal lingual nerve terminals in an in vitro intra-arterially perfused rat tongue preparation

1 reference

12 December 2020

ATP regulates muscarine-sensitive potassium current in dissociated bull-frog primary afferent neurones

1 reference

12 December 2020

Subclassified acutely dissociated cells of rat DRG: histochemistry and patterns of capsaicin-, proton-, and ATP-activated currents

1 reference

12 December 2020

Distribution of P2X3 receptors in the rat trigeminal ganglion after inferior alveolar nerve injury

1 reference

12 December 2020

Characterization of cultured dorsal root ganglion neuron P2X receptors

1 reference

12 December 2020

10.1113/JPHYSIOL.2003.049114

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14514872%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

PMC publication ID

2343624

0 references

1 reference