Islet amyloid: an enigma of type 2 diabetes (Q35485159)

8 August 2017

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title

Islet amyloid: an enigma of type 2 diabetes (English)

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8 August 2017

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A. Clark

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1425123

25 September 2022

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1425123

25 September 2022

publication date

1 July 1992

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Diabetes/metabolism reviews

8 August 2017

published in

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8 August 2017

volume

8

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8 August 2017

issue

2

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8 August 2017

page(s)

117-132

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Islet amyloid formed from diabetes-associated peptide may be pathogenic in type-2 diabetes

8 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

A STUDY OF THE PATHOLOGICAL ANATOMY OF THE PANCREAS IN NINETY CASES OF DIABETES MELLITUS.

1 reference

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7 January 2021

Quantitative estimation of the pancreatic islet tissue in diabetic subjects

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https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Amyloid deposits and amyloidosis: the beta-fibrilloses (second of two parts).

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https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Characterization of amyloid fibril proteins from medullary carcinoma of the thyroid

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https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

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https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

On the Relation of Chronic Interstitial Pancreatitis to the Islands of Langerhans and to Diabetes Melutus

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

THE RELATION OE DIABETES MELLITUS TO LESIONS OF THE PANCREAS. HYALINE DEGENERATION OF THE ISLANDS OE LANGERHANS.

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Hyalinization of the islet of Langerhans in diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

[Amyloid of islets of Langerhans and its relation to diabetes mellitus (author's transl)]

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Cellular composition of the human diabetic pancreas

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

The relation of islet amyloid to the clinical type of diabetes

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Non-uniform distribution of islet amyloid in the pancreas of 'maturity-onset' diabetic patients

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Islet amyloid polypeptide in diabetic and non-diabetic Pima Indians

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Differential volumetry of A,B and D cells in the pancreatic islets of diabetic and nondiabetic subjects

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Endocrine pancreas in cystic fibrosis: An immunohistochemical study

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

A novel peptide in the calcitonin gene related peptide family as an amyloid fibril protein in the endocrine pancreas

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

The amylin superfamily: a novel grouping of biologically active polypeptides related to the insulin A-chain

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Amyloid fibrils formed from a segment of the pancreatic islet amyloid protein

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Solution structures of calcitonin-gene-related-peptide analogues of calcitonin-gene-related peptide and amylin

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Structure of prealbumin: secondary, tertiary and quaternary interactions determined by Fourier refinement at 1.8 A

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Three-dimensional structure of beta 2-microglobulin

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Sequences of islet amyloid polypeptide precursors of an old world monkey, the pig-tailed macaque (Macaca nemestrina), and the dog (Canis familiaris)

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Canine IAPP cDNA sequence provides important clues regarding diabetogenesis and amyloidogenesis in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Structure of cat islet amyloid polypeptide and identification of amino acid residues of potential significance for islet amyloid formation

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Sequence of a cDNA encoding Syrian hamster islet amyloid polypeptide precursor

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Amyloid in the pancreatic islets of the cougar (Felis concolor) is derived from islet amyloid polypeptide (IAPP)

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Rat amylin: cloning and tissue-specific expression in pancreatic islets

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Regional distribution and molecular forms of rat islet amyloid polypeptide

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Expression of the rat amylin (IAPP/DAP) gene

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Conservation of the sequence of islet amyloid polypeptide in five mammals is consistent with its putative role as an islet hormone

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Cloning of complementary DNAs encoding islet amyloid polypeptide, insulin, and glucagon precursors from a New World rodent, the degu, Octodon degus

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Synthetic peptide homologous to beta protein from Alzheimer disease forms amyloid-like fibrils in vitro

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Islet amyloid polypeptide and calcitonin gene-related peptide immunoreactivity in amyloid and tumor cells of canine pancreatic endocrine tumors

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Amino acid sequence from degu islet amyloid-derived insulin shows unique sequence characteristics.

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Biology of serum amyloid P component

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

The pancreas in recent-onset type 1 (insulin-dependent) diabetes mellitus: insulin content of islets, insulitis and associated changes in the exocrine acinar tissue

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Fine structure of islets of Langerhans in insular amyloidosis

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Islet amyloid and type 2 diabetes

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Co-localization of islet amyloid polypeptide and insulin in the B cell secretory granules of the human pancreatic islets

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Localisation of islet amyloid peptide in lipofuscin bodies and secretory granules of human B-cells and in islets of type-2 diabetic subjects

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Islet amyloid polypeptide (IAPP) and pro-IAPP immunoreactivity in human islets of Langerhans

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Localisation of islet amyloid polypeptide and its carboxy terminal flanking peptide in islets of diabetic man and monkey.

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Islet amyloid polypeptide immunoreactivity in the human fetal pancreas

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Islet Amyloid Polypeptide and Insulin Expression Are Controlled Differently in Primary and Transformed Islet Cells

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Islet amyloid polypeptide (IAPP) in the gastrointestinal tract and pancreas of man and rat.

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Islet amyloid, islet-amyloid polypeptide, and diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Immunohistochemical morphometry of pancreatic endocrine cells in diabetic, normoglycaemic glucose-intolerant and normal cats

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Concordance for type 2 (non-insulin-dependent) diabetes mellitus in male twins

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Linkage of type 2 diabetes to the glucokinase gene

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Islet amyloid polypeptide: identification and chromosomal localization of the human gene

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Human islet amyloid polypeptide gene: complete nucleotide sequence, chromosomal localization, and evolutionary history

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

The complete islet amyloid polypeptide precursor is encoded by two exons

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Is islet amyloid polypeptide a significant factor in pathogenesis or pathophysiology of diabetes?

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Primary structure of an amyloid prealbumin variant in familial polyneuropathy of Jewish origin

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Islet amyloid polypeptide (amylin): no evidence of an abnormal precursor sequence in 25 type 2 (non-insulin-dependent) diabetic patients

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

An RFLP associated with insulinoma amyloid polypeptide locus (IAPP)

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Non-linkage of the islet amyloid polypeptide gene with Type 2 (non-insulin-dependent) diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Islet amyloid polypeptide (IAPP):cDNA cloning and identification of an amyloidogenic region associated with the species-specific occurrence of age-related diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

IAPP/amylin gene transcriptional control region: evidence for negative regulation

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Coordinate Regulation of Amylin and Insulin Expression in Response to Hypoglycemia and Fasting

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Depletion of islet amyloid polypeptide in the spontaneously diabetic (BB) Wistar rat

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Amylin secretion from the rat pancreas and its selective loss after streptozotocin treatment

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Evidence of cosecretion of islet amyloid polypeptide and insulin by beta-cells

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Release of Amylin From Perfused Rat Pancreas in Response to Glucose, Arginine, β-Hydroxybutyrate, and Gliclazide

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Co-secretion of amylin and insulin from cultured islet β-cells: Modulation by nutrient secretagogues, islet hormones and hypoglycemic agents

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Islet Amyloid Polypeptide and Insulin Secretion From Isolated Perfused Pancreas of Fed, Fasted, Glucose-Treated, and Dexamethasone-Treated Rats

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Islet amyloid polypeptide-like immunoreactivity (amylin) in rats treated with dexamethasone and streptozotocin

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Islet amyloid polypeptide, a novel pancreatic peptide, is a circulating hormone secreted under glucose stimulation

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Islet amyloid polypeptide response to glucose, insulin, and somatostatin analogue administration

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Effects of meal ingestion on plasma amylin concentration in NIDDM and nondiabetic humans.

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Islet-amyloid polypeptide in human plasma

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Plasma islet amyloid polypeptide (Amylin) levels and their responses to oral glucose in type 2 (non-insulin-dependent) diabetic patients

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Decrease of Stimulated Amylin Release Precedes Impairment of Insulin Secretion in Type II Diabetes

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Basal and stimulated plasma levels of pancreatic amylin indicate its co-secretion with insulin in humans

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Effects of ciglitazone on endogenous plasma islet amyloid polypeptide and insulin sensitivity in obese-diabetic viable yellow mice

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Hyperproinsulinemia and amyloid in NIDDM. Clues to etiology of islet beta-cell dysfunction?

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Amylin found in amyloid deposits in human type 2 diabetes mellitus may be a hormone that regulates glycogen metabolism in skeletal muscle

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Pancreatic amylin and calcitonin gene-related peptide cause resistance to insulin in skeletal muscle in vitro.

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

The effects of amylin on carbohydrate metabolism in skeletal muscle in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Human islet amyloid polypeptide at pharmacological levels inhibits insulin and phorbol ester-stimulated glucose transport in in vitro incubated human muscle strips.

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Amylin activates glycogen phosphorylase in the isolated soleus muscle of the rat.

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

In vivo insulin resistance induced by amylin primarily through inhibition of insulin-stimulated glycogen synthesis in skeletal muscle.

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Amylin-induced in vivo insulin resistance in conscious rats: the liver is more sensitive to amylin than peripheral tissues

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Induction of insulin resistance in vivo by amylin and calcitonin gene-related peptide

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Islet amyloid polypeptide amide causes peripheral insulin resistance in vivo in dogs.

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Failure of islet amyloid polypeptide to inhibit basal and glucose-stimulated insulin secretion in model experiments in mice and rats

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

The effect of islet amyloid polypeptide (amylin) and calcitonin gene-related peptide on glucose removal in the anaesthetized rat and on insulin secretion from rat pancreatic islets in vitro

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Lack of Effect of Islet Amyloid Polypeptide in Causing Insulin Resistance in Conscious Dogs During Euglycemic Clamp Studies

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Cross-reactivity of amylin with calcitonin-gene-related peptide binding sites in rat liver and skeletal muscle membranes

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Activation of adenylate cyclase by islet amyloid polypeptide with COOH-terminal amide via calcitonin gene-related peptide receptors on rat liver plasma membranes

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

In vivo and in vitro effects of amylin and amylin-amide on calcium metabolism in the rat and rabbit

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Amylin-amide: a new bone-conserving peptide from the pancreas

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Calcitonin gene-related peptide: occurrence in pancreatic islets in the mouse and the rat and inhibition of insulin secretion in the mouse

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Neuropeptide Y and calcitonin gene-related peptide: effects on glucagon and insulin secretion in the mouse

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Effects of calcitonin gene-related peptide (CGRP) on islet hormone secretion in the pig.

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Dual effects of calcitonin gene-related peptide on insulin secretion in the perfused dog pancreas

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Islet amyloid polypeptide inhibits glucose-stimulated insulin secretion from isolated rat pancreatic islets

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Inhibitory effect of rat amylin on the insulin responses to glucose and arginine in the perfused rat pancreas

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Islet amyloid polypeptide (IAPP;Amylin) influences the endocrine but not the exocrine rat pancreas

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Islet amyloid polypeptide (IAPP) does not inhibit glucose-stimulated insulin secretion from isolated perfused rat pancreas

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Effects of amidated rat islet amyloid polypeptide on glucose-stimulated insulin secretion in vivo and in vitro in rats

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Lack of islet amyloid polypeptide regulation of insulin biosynthesis or secretion in normal rat islets

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Calcitonin gene-related peptide is a potent vasodilator

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Antagonistic Effect of Human α-Calcitonin Gene–Related Peptide (8–37) on Regional Hemodynamic Actions of Rat Islet Amyloid Polypeptide in Conscious Long-Evans Rats

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Immunocytochemical identification of islet cells and nerve fibers containing calcitonin gene-related peptide-like immunoreactivity in the rat pancreas

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Daily amylin replacement reverses hepatic glycogen depletion in insulin-treated streptozotocin diabetic rats

1 reference

https://api.crossref.org/works/10.1002%2FDMR.5610080204

7 January 2021

Identifiers

DOI

10.1002/DMR.5610080204

0 references

1 reference