NADPH oxidase deficiency regulates Th lineage commitment and modulates autoimmunity. (Q35306229)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20881184%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

title

NADPH oxidase deficiency regulates Th lineage commitment and modulates autoimmunity (English)

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14 February 2020

1 reference

2

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14 February 2020

Carla M Cuda

4

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14 February 2020

author name string

Hubert M Tse

1

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14 February 2020

Chad Steele

3

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14 February 2020

Laurence Morel

5

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14 February 2020

Jon D Piganelli

6

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14 February 2020

Clayton E Mathews

7

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14 February 2020

language of work or name

English

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publication date

29 September 2010

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14 February 2020

published in

Journal of Immunology

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14 February 2020

volume

185

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14 February 2020

issue

9

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14 February 2020

page(s)

5247-5258

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TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages.

14 February 2020

cites work

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

12 July 2018

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mt-Nd2a suppresses reactive oxygen species production by mitochondrial complexes I and III.

12 July 2018

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Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis

12 July 2018

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Stat3 and Stat4 direct development of IL-17-secreting Th cells.

12 July 2018

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STAT3 regulates cytokine-mediated generation of inflammatory helper T cells

12 July 2018

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Nuclear and mitochondrial interaction involving mt-Nd2 leads to increased mitochondrial reactive oxygen species production

12 July 2018

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An absence of reactive oxygen species improves the resolution of lung influenza infection.

12 July 2018

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TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

12 July 2018

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Interleukin-17--induced interleukin-8 release in human airway smooth muscle cells: role for mitogen-activated kinases and nuclear factor-kappaB.

12 July 2018

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Ncf1 (p47phox) polymorphism determines oxidative burst and the severity of arthritis in rats and mice

12 July 2018

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IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

12 July 2018

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Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene

12 July 2018

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T cells express a phagocyte-type NADPH oxidase that is activated after T cell receptor stimulation

12 July 2018

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Redox signaling and the MAP kinase pathways

12 July 2018

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Positional identification of Ncf1 as a gene that regulates arthritis severity in rats

12 July 2018

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A metalloporphyrin-based superoxide dismutase mimic inhibits adoptive transfer of autoimmune diabetes by a diabetogenic T-cell clone

12 July 2018

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Deficiency of small GTPase Rac2 affects T cell activation

12 July 2018

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Unusual resistance of ALR/Lt mouse beta cells to autoimmune destruction: role for beta cell-expressed resistance determinants

12 July 2018

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Resistance of ALR/Lt islets to free radical-mediated diabetogenic stress is inherited as a dominant trait.

12 July 2018

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Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense

12 July 2018

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12 July 2018

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Pancreatic beta cell-specific expression of thioredoxin, an antioxidative and antiapoptotic protein, prevents autoimmune and streptozotocin-induced diabetes

12 July 2018

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12 July 2018

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Inflammatory cytokines enhance the in vivo clonal expansion and differentiation of antigen-activated CD4+ T cells

12 July 2018

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T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines

12 July 2018

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Redox regulation of cell signalling

12 July 2018

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Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans

12 July 2018

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Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases.

12 July 2018

1 reference

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Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190397

Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2

12 July 2018

1 reference

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Role of IL-23 in mobilization of immunoregulatory nitric oxide- or superoxide-producing Gr-1+ cells from bone marrow.

12 July 2018

1 reference

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Disruption of innate-mediated proinflammatory cytokine and reactive oxygen species third signal leads to antigen-specific hyporesponsiveness.

26 September 2018

1 reference

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In the absence of reactive oxygen species, T cells default to a Th1 phenotype and mediate protection against pulmonary Cryptococcus neoformans infection

26 September 2018

1 reference

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Mechanisms underlying resistance of pancreatic islets from ALR/Lt mice to cytokine-induced destruction

26 September 2018

1 reference

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MnSOD and catalase transgenes demonstrate that protection of islets from oxidative stress does not alter cytokine toxicity

26 September 2018

1 reference

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The diabetes susceptibility locus Idd5.1 on mouse chromosome 1 regulates ICOS expression and modulates murine experimental autoimmune encephalomyelitis

26 September 2018

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Mechanistic analysis of the immunomodulatory effects of a catalytic antioxidant on antigen-presenting cells: implication for their use in targeting oxidation-reduction reactions in innate immunity

26 September 2018

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Genetic control of neutrophil superoxide production in diabetes-resistant ALR/Lt mice

26 September 2018

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Activation of the mitogen-activated protein kinase signaling pathway is instrumental in determining the ability of Mycobacterium avium to grow in murine macrophages

26 September 2018

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Constitutive differences in antioxidant defense status distinguish alloxan-resistant and alloxan-susceptible mice.

26 September 2018

1 reference

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Inflammatory cytokines provide a third signal for activation of naive CD4+ and CD8+ T cells

26 September 2018

1 reference

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Defective activation of T suppressor cell function in nonobese diabetic mice. Potential relation to cytokine deficiencies

15 November 2018

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12 December 2020

Intrathymic islet cell transplantation reduces beta-cell autoimmunity and prevents diabetes in NOD/Lt mice

1 reference

12 December 2020

T helper cell subsets in insulin-dependent diabetes

1 reference

12 December 2020

Splenic macrophages from the NOD mouse are defective in the ability to present antigen

1 reference

12 December 2020

Complementary action of antioxidant enzymes in the protection of bioengineered insulin-producing RINm5F cells against the toxicity of reactive oxygen species

1 reference

12 December 2020

Protection against the co-operative toxicity of nitric oxide and oxygen free radicals by overexpression of antioxidant enzymes in bioengineered insulin-producing RINm5F cells

1 reference

12 December 2020

Effector function of diabetogenic CD4 Th1 T cell clones: a central role for TNF-alpha

1 reference

12 December 2020

Therapeutic efficacy of IL-17 neutralization in murine experimental autoimmune encephalomyelitis

1 reference

12 December 2020

Metallothionein and catalase sensitize to diabetes in nonobese diabetic mice: reactive oxygen species may have a protective role in pancreatic beta-cells

1 reference

12 December 2020

IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis

1 reference

12 December 2020

Anti-IL-12 antibody prevents the development and progression of multiple sclerosis-like relapsing--remitting demyelinating disease in NOD mice induced with myelin oligodendrocyte glycoprotein peptide

1 reference

12 December 2020

P47(phox)-deficient NADPH oxidase defect in neutrophils of diabetic mouse strains, C57BL/6J-m db/db and db/+

1 reference

12 December 2020

Role of the Guanosine Triphosphatase Rac2 in T Helper 1 Cell Differentiation

1 reference

12 December 2020

Increased entry into the IFN-gamma effector pathway by CD4+ T cells selected by I-Ag7 on a nonobese diabetic versus C57BL/6 genetic background

1 reference

12 December 2020

Genetic analysis of resistance to Type-1 Diabetes in ALR/Lt mice, a NOD-related strain with defenses against autoimmune-mediated diabetogenic stress

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1001472

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20881184%20AND%20SRC:MED&resulttype=core&format=json

release_bvxwxtliyvce5kfznkymmk3kmy

14 February 2020

Fatcat ID

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Fatcat

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24 November 2022

mapped directly with Wikidata item

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20881184%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

PubMed publication ID

20881184

1 reference