B-lymphocyte depletion reduces skin fibrosis and autoimmunity in the tight-skin mouse model for systemic sclerosis (Q35222002)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16936269%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

title

B-lymphocyte depletion reduces skin fibrosis and autoimmunity in the tight-skin mouse model for systemic sclerosis (English)

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29 December 2019

1

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Kazuhiro Komura

10

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7

Takashi Matsushita

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author name string

Yasuhito Hamaguchi

2

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Koichi Yanaba

3

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29 December 2019

Jean-David Bouaziz

4

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29 December 2019

Junji Uchida

5

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29 December 2019

Manabu Fujimoto

6

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29 December 2019

Yukiyo Matsushita

8

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Mayuka Horikawa

9

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29 December 2019

Kazuhiko Takehara

11

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Shinichi Sato

12

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29 December 2019

Thomas F Tedder

13

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29 December 2019

language of work or name

English

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publication date

1 September 2006

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The American Journal of Pathology

29 December 2019

published in

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volume

169

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issue

3

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page(s)

954-966

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Antibody isotype-specific engagement of Fcgamma receptors regulates B lymphocyte depletion during CD20 immunotherapy.

29 December 2019

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The CD19-CD21 signal transduction complex of B lymphocytes regulates the balance between health and autoimmune disease: systemic sclerosis as a model system

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B Lymphocyte signaling established by the CD19/CD22 loop regulates autoimmunity in the tight-skin mouse

13 July 2018

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The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor-dependent mechanisms during anti-CD20 antibody immunotherapy

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Mouse CD20 expression and function

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Systemic and cell type-specific gene expression patterns in scleroderma skin

13 July 2018

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Role of profibrogenic cytokines secreted by T cells in fibrotic processes in scleroderma

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CD19-dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouse

13 July 2018

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Disrupting the IL-4 gene rescues mice homozygous for the tight-skin mutation from embryonic death and diminishes TGF-beta production by fibroblasts

13 July 2018

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A novel method to compensate for different amplification efficiencies between patient DNA samples in quantitative real-time PCR.

13 July 2018

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Lack of skin fibrosis in tight skin (TSK) mice with targeted mutation in the interleukin-4R alpha and transforming growth factor-beta genes.

13 July 2018

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Induction of skin fibrosis in mice expressing a mutated fibrillin-1 gene.

13 July 2018

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New insights into the assembly of extracellular microfibrils from the analysis of the fibrillin 1 mutation in the tight skin mouse

13 July 2018

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Anti-IL-4 treatment prevents dermal collagen deposition in the tight-skin mouse model of scleroderma

13 July 2018

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CD20 (pan-B cell antigen) expression on bone marrow-derived T cells

13 July 2018

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Autoantibody reactive with three classes of RNA polymerases in sera from patients with systemic sclerosis

13 July 2018

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Clinical correlations and prognosis based on serum autoantibodies in patients with systemic sclerosis

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Tight-skin, a new mutation of the mouse causing excessive growth of connective tissue and skeleton

13 July 2018

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26 September 2018

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26 September 2018

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26 September 2018

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Effect of IL-12 encoding plasmid administration on tight-skin mouse

26 September 2018

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12 December 2020

The tight-skin mouse: physical and biochemical properties of the skin

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12 December 2020

Increased collagen biosynthesis and increased expression of type I and type III procollagen genes in tight skin (TSK) mouse fibroblasts

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12 December 2020

Scleroderma (systemic sclerosis): classification, subsets and pathogenesis

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12 December 2020

Adoptive transfer of tsk skin fibrosis to +/+ recipients by tsk bone marrow and spleen cells

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12 December 2020

Polyclonal B lymphocyte activation in progressive systemic sclerosis

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12 December 2020

Cd20 (pan‐B cell) antigen is expressed at a low level on a subpopulation of human T lymphocytes

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12 December 2020

Immunological characterization of (tight skin/NZB)F1 hybrid mice with connective tissue and autoimmune features resembling human systemic sclerosis

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12 December 2020

Induction of skin fibrosis and autoantibodies by infusion of immunocompetent cells from tight skin mice into C57BL/6 Pa/Pa mice

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12 December 2020

A role for CD4+ T cells in the pathogenesis of skin fibrosis in tight skin mice

1 reference

12 December 2020

Development of the tight-skin phenotype in immune-deficient mice

1 reference

12 December 2020

The role of mast cells in the development of skin fibrosis in tight-skin mutant mice

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12 December 2020

Correlation between the concentration of serum anti-topoisomerase I autoantibodies and histological and biochemical alterations in the skin of tight skin mice

1 reference

12 December 2020

A tandem duplication within the fibrillin 1 gene is associated with the mouse tight skin mutation

1 reference

12 December 2020

CD19 regulates B lymphocyte signaling thresholds critical for the development of B-1 lineage cells and autoimmunity

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12 December 2020

B-cell Deficiency does not Abrogate Development of Cutaneous Hyperplasia in Mice Inheriting the Defective Fibrillin-1 Gene

1 reference

12 December 2020

The mouse tight skin (Tsk) phenotype is not dependent on the presence of mature T and B lymphocytes

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12 December 2020

Spontaneous occurrence of anti-fibrillin-1 autoantibodies in tight-skin mice

1 reference

12 December 2020

Autoantibodies to the extracellular matrix microfibrillar protein, fibrillin-1, in patients with scleroderma and other connective tissue diseases

1 reference

12 December 2020

A role for T helper 2 cells in mediating skin fibrosis in tight-skin mice

1 reference

12 December 2020

Dendritic cell-derived IL-12 promotes B cell induction of Th2 differentiation: a feedback regulation of Th1 development

1 reference

12 December 2020

Association of a functional CD19 polymorphism with susceptibility to systemic sclerosis

1 reference

12 December 2020

Fibulin-2 and fibulin-5 alterations in tsk mice associated with disorganized hypodermal elastic fibers and skin tethering

1 reference

12 December 2020

CpG oligodeoxynucleotides prevent the development of scleroderma-like syndrome in tight-skin mice by stimulating a Th1 immune response

1 reference

12 December 2020

Analysis of the tight skin (Tsk1/+) mouse as a model for testing antifibrotic agents

1 reference

12 December 2020

Reconstitution of peripheral blood B cells after depletion with rituximab in patients with rheumatoid arthritis

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12 December 2020

Quantitative genetic variation in CD19 expression correlates with autoimmunity

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12 December 2020

10.2353/AJPATH.2006.060205

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16936269%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

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29 December 2019

PubMed publication ID

16936269

1 reference