CXCR7/CXCR4 heterodimer constitutively recruits beta-arrestin to enhance cell migration. (Q35213405)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21730065%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

title

CXCR7/CXCR4 heterodimer constitutively recruits beta-arrestin to enhance cell migration (English)

1 reference

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6 February 2020

1 reference

5

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6 February 2020

author name string

Fabien M Décaillot

1

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6 February 2020

Manija A Kazmi

2

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6 February 2020

Ying Lin

3

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6 February 2020

Sarmistha Ray-Saha

4

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6 February 2020

Pallavi Sachdev

6

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6 February 2020

language of work or name

English

0 references

publication date

5 July 2011

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Journal of Biological Chemistry

6 February 2020

published in

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6 February 2020

volume

286

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6 February 2020

issue

37

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6 February 2020

page(s)

32188-32197

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Atypical chemokine receptors

6 February 2020

cites work

1 reference

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13 July 2018

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13 July 2018

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CXCR4 mediates the proliferation of glioblastoma progenitor cells

13 July 2018

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13 July 2018

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13 July 2018

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Arrestin 3 mediates endocytosis of CCR7 following ligation of CCL19 but not CCL21.

13 July 2018

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Structural Basis of CXCR4 Sulfotyrosine Recognition by the Chemokine SDF-1/CXCL12

13 July 2018

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CXCR7, CXCR4 and CXCL12: an eccentric trio?

13 July 2018

1 reference

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Essential but differential role for CXCR4 and CXCR7 in the therapeutic homing of human renal progenitor cells.

13 July 2018

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The role of CXCR7/RDC1 as a chemokine receptor for CXCL12/SDF-1 in prostate cancer

13 July 2018

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CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature

13 July 2018

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Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7

13 July 2018

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In situ expression of IFN-gamma-inducible T cell alpha chemoattractant in breast cancer mounts an enhanced specific anti-tumor immunity which leads to tumor regression

13 July 2018

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Beta-arrestin-biased ligands at seven-transmembrane receptors

13 July 2018

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LRRC4 inhibits glioblastoma cell proliferation, migration, and angiogenesis by downregulating pleiotropic cytokine expression and responses

13 July 2018

1 reference

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Receptor heterodimerization leads to a switch in signaling: beta-arrestin2-mediated ERK activation by mu-delta opioid receptor heterodimers

13 July 2018

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13 July 2018

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A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development

13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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Bioluminescence resonance energy transfer reveals ligand-induced conformational changes in CXCR4 homo- and heterodimers.

13 July 2018

1 reference

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Constitutive protease-activated receptor-2-mediated migration of MDA MB-231 breast cancer cells requires both beta-arrestin-1 and -2.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173186

Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173186

Heterodimerization of V1a and V2 vasopressin receptors determines the interaction with beta-arrestin and their trafficking patterns

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173186

Roles of G-protein-coupled receptor dimerization

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173186

Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors

13 July 2018

1 reference

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Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2.

13 July 2018

1 reference

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A beta-arrestin-dependent scaffold is associated with prolonged MAPK activation in pseudopodia during protease-activated receptor-2-induced chemotaxis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173186

Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173186

Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173186

Chemokine receptors: multifaceted therapeutic targets

13 July 2018

1 reference

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Chemokine receptor homo- or heterodimerization activates distinct signaling pathways

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173186

Involvement of chemokine receptors in breast cancer metastasis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173186

International union of pharmacology. XXII. Nomenclature for chemokine receptors

13 July 2018

1 reference

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beta-arrestin differentially regulates the chemokine receptor CXCR4-mediated signaling and receptor internalization, and this implicates multiple interaction sites between beta-arrestin and CXCR4

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173186

Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173186

Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173186

Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173186

CXCL12, CXCR4 and CXCR7 expression in brain metastases

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173186

CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173186

Higher expression of chemokine receptor CXCR7 is linked to early and metastatic recurrence in pathological stage I nonsmall cell lung cancer

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173186

Allosteric transinhibition by specific antagonists in CCR2/CXCR4 heterodimers

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173186

Allosteric modulation of binding properties between units of chemokine receptor homo- and hetero-oligomers

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173186

Paired activation of two components within muscarinic M3 receptor dimers is required for recruitment of beta-arrestin-1 to the plasma membrane

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173186

Evidence for negative binding cooperativity within CCR5-CCR2b heterodimers

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173186

Rapid Incorporation of Functional Rhodopsin into Nanoscale Apolipoprotein Bound Bilayer (NABB) Particles

26 September 2018

1 reference

12 December 2020

Concomitant CXCR4 and CXCR7 Expression Predicts Poor Prognosis in Renal Cancer

1 reference

12 December 2020

Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4

1 reference

12 December 2020

Chemokines and cancer

1 reference

12 December 2020

The role of GPCR dimerisation/oligomerisation in receptor signalling

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M111.277038

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21730065%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21730065%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

PubMed publication ID

21730065

1 reference