Peptides come round: using SICLOPPS libraries for early stage drug discovery (Q35209857)

7 August 2017

title

Peptides come round: using SICLOPPS libraries for early stage drug discovery (English)

1 reference

7 August 2017

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043886%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Katherine R Lennard

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043886%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

language of work or name

English

0 references

publication date

9 July 2014

1 reference

Chemistry—A European Journal

7 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043886%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043886%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

issue

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043886%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

10608-10614

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043886%20AND%20SRC:MED&resulttype=core&format=json

The exploration of macrocycles for drug discovery--an underexploited structural class

13 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Macrocycles Are Great Cycles: Applications, Opportunities, and Challenges of Synthetic Macrocycles in Drug Discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Bicyclic peptide ligands pulled out of cysteine-rich peptide libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Directed evolution of bicyclic peptides for therapeutic application

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Diverse backbone-cyclized peptides via codon reprogramming

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Discovery of macrocyclic peptides armed with a mechanism-based warhead: isoform-selective inhibition of human deacetylase SIRT2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Modular assembly of macrocyclic organo-peptide hybrids using synthetic and genetically encoded precursors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Contemporary strategies for peptide macrocyclization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Small-molecule discovery from DNA-encoded chemical libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Synthesis of bicyclic organo-peptide hybrids via oxime/intein-mediated macrocyclization followed by disulfide bond formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

A highly flexible tRNA acylation method for non-natural polypeptide synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

In vitro selection of anti-Akt2 thioether-macrocyclic peptides leading to isoform-selective inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

In vitro selection of multiple libraries created by genetic code reprogramming to discover macrocyclic peptides that antagonize VEGFR2 activity in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Flexizyme-mediated genetic reprogramming as a tool for noncanonical peptide synthesis and drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Phage-encoded combinatorial chemical libraries based on bicyclic peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

InBase, the Intein Database

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Protein trans-splicing by a split intein encoded in a split DnaE gene of Synechocystis sp. PCC6803

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Production of cyclic peptides and proteins in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Structural requirements for the biosynthesis of backbone cyclic peptide libraries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Split-intein mediated circular ligation used in the synthesis of cyclic peptide libraries in E. coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

A systematic method for identifying small-molecule modulators of protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Genetically selected cyclic-peptide inhibitors of AICAR transformylase homodimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Functional profiling of p53-binding sites in Hdm2 and Hdmx using a genetic selection system

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Cyclic peptide inhibitors of the β-sliding clamp in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Inhibition of HIV budding by a genetically selected cyclic peptide targeting the Gag-TSG101 interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Discovery of antibacterial cyclic peptides that inhibit the ClpXP protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Intracellular detection and evolution of site-specific proteases using a genetic selection system

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Genetic selection of cyclic peptide Dam methyltransferase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Intein-mediated cyclization of randomized peptides in the periplasm of Escherichia coli and their extracellular secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Evolution of cyclic peptide protease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Inhibition of transcription factors with small organic molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

A cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Retrovirally delivered random cyclic Peptide libraries yield inhibitors of interleukin-4 signaling in human B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Rapid selection of cyclic peptides that reduce alpha-synuclein toxicity in yeast and animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

A genetic screen for isolating "lariat" Peptide inhibitors of protein function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Allosteric lariat peptide inhibitors of Abl kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

Targeting tumour proliferation with a small-molecule inhibitor of AICAR transformylase homodimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201403117

21 January 2018

Identifiers

DOI

10.1002/CHEM.201403117

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043886%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference