Functional Dissection of a Candida albicans Zinc Cluster Transcription Factor, the Multidrug Resistance Regulator Mrr1 (Q35191806)

https://api.crossref.org/works/10.1128/EC.05100-11

7 August 2017

title

Functional Dissection of a Candida albicans Zinc Cluster Transcription Factor, the Multidrug Resistance Regulator Mrr1 (English)

1 reference

4 December 2024

main subject

multiple drug resistance

1 reference

1 reference

4

Joachim Morschhäuser

1 reference

7 August 2017

Sabrina Schubert

1

1 reference

7 August 2017

Christina Popp

series ordinal

2

1 reference

7 August 2017

P. David Rogers

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21685320

4 December 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21685320

4 December 2024

publication date

17 June 2011

1 reference

full work available at URL

7 August 2017

https://ec.asm.org/content/10/8/1110.full.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21685320

https://europepmc.org/articles/PMC3165443

4 December 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21685320

https://europepmc.org/articles/PMC3165443?pdf=render

4 December 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21685320

https://doi.org/10.1128/ec.05100-11

4 December 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21685320

https://journals.asm.org/doi/pdf/10.1128/EC.05100-11

4 December 2024

1 reference

https://api.crossref.org/works/10.1128/EC.05100-11

4 December 2024

1 reference

7 August 2017

volume

10

1 reference

7 August 2017

issue

8

1 reference

7 August 2017

page(s)

1110-1121

1 reference

Regulation of efflux pump expression and drug resistance by the transcription factors Mrr1, Upc2, and Cap1 in Candida albicans

7 August 2017

cites work

1 reference

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Differential requirement of the transcription factor Mcm1 for activation of the Candida albicans multidrug efflux pump MDR1 by its regulators Mrr1 and Cap1.

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An A643T mutation in the transcription factor Upc2p causes constitutive ERG11 upregulation and increased fluconazole resistance in Candida albicans

13 July 2018

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Functional analysis of cis- and trans-acting elements of the Candida albicans CDR2 promoter with a novel promoter reporter system.

13 July 2018

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Identification of the Candida albicans Cap1p regulon.

13 July 2018

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Gain of function mutations in CgPDR1 of Candida glabrata not only mediate antifungal resistance but also enhance virulence

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Gain-of-function mutations in the transcription factor MRR1 are responsible for overexpression of the MDR1 efflux pump in fluconazole-resistant Candida dubliniensis strains

13 July 2018

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Mutations in the multi-drug resistance regulator MRR1, followed by loss of heterozygosity, are the main cause of MDR1 overexpression in fluconazole-resistant Candida albicans strains

13 July 2018

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A gain-of-function mutation in the transcription factor Upc2p causes upregulation of ergosterol biosynthesis genes and increased fluconazole resistance in a clinical Candida albicans isolate.

13 July 2018

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A nuclear receptor-like pathway regulating multidrug resistance in fungi

13 July 2018

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The transcription factor Mrr1p controls expression of the MDR1 efflux pump and mediates multidrug resistance in Candida albicans

13 July 2018

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Genotypic evolution of azole resistance mechanisms in sequential Candida albicans isolates

13 July 2018

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Transcriptional activation domains of the Candida albicans Gcn4p and Gal4p homologs

13 July 2018

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A fungal family of transcriptional regulators: the zinc cluster proteins

13 July 2018

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A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans

13 July 2018

1 reference

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Candida albicans zinc cluster protein Upc2p confers resistance to antifungal drugs and is an activator of ergosterol biosynthetic genes

13 July 2018

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13 July 2018

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TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2.

13 July 2018

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13 July 2018

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Comparison of gene expression profiles of Candida albicans azole-resistant clinical isolates and laboratory strains exposed to drugs inducing multidrug transporters

13 July 2018

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The genetic basis of fluconazole resistance development in Candida albicans

13 July 2018

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A common drug-responsive element mediates the upregulation of the Candida albicans ABC transporters CDR1 and CDR2, two genes involved in antifungal drug resistance

13 July 2018

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Overexpression of a cloned IMP dehydrogenase gene of Candida albicans confers resistance to the specific inhibitor mycophenolic acid

13 July 2018

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13 July 2018

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13 July 2018

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27 September 2018

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27 September 2018

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27 September 2018

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27 September 2018

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Expression of one-hybrid fusions with Staphylococcus aureus lexA in Candida albicans confirms that Nrg1 is a transcriptional repressor and that Gcn4 is a transcriptional activator

27 September 2018

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The SAT1 flipper, an optimized tool for gene disruption in Candida albicans

27 September 2018

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Isolation of the Candida albicans gene for orotidine-5'-phosphate decarboxylase by complementation of S. cerevisiae ura3 and E. coli pyrF mutations

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21685320

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/EC.05100-11

1 reference

7 August 2017

1 reference

7 August 2017

1 reference