WT1 in acute leukemia, chronic myelogenous leukemia and myelodysplastic syndrome: therapeutic potential of WT1 targeted therapies (Q35166856)

6 August 2017

1 reference

title

WT1 in acute leukemia, chronic myelogenous leukemia and myelodysplastic syndrome: therapeutic potential of WT1 targeted therapies (English)

1 reference

6 August 2017

1 reference

myelodysplastic syndrome

1 reference

1 reference

Rosenfeld C

1

1 reference

6 August 2017

Cheever MA

series ordinal

2

1 reference

6 August 2017

Gaiger A

series ordinal

3

1 reference

6 August 2017

publication date

1 July 2003

1 reference

6 August 2017

1 reference

6 August 2017

volume

17

1 reference

6 August 2017

issue

7

1 reference

6 August 2017

page(s)

1301-1312

1 reference

Randomised comparison of addition of autologous bone-marrow transplantation to intensive chemotherapy for acute myeloid leukaemia in first remission: results of MRC AML 10 trial. UK Medical Research Council Adult and Children's Leukaemia Working Par

6 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Donor lymphocyte infusion for relapsed chronic myelogenous leukemia: prognostic relevance of the initial cell dose

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

The potential for antitumor vaccination in acute myelogenous leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

The World Health Organization classification of hematological malignancies report of the Clinical Advisory Committee Meeting, Airlie House, Virginia, November 1997.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

WT1 proteins: functions in growth and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Altered expression of the WT1 wilms tumor suppressor gene in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

New insights into paroxysmal nocturnal hemoglobinuria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

HLA class II haplotype and quantitation of WT1 RNA in Japanese patients with paroxysmal nocturnal hemoglobinuria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Mutation analysis of the WT1 gene in myelodysplastic syndromes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Constitutive expression of the Wilms' tumor gene WT1 inhibits the differentiation of myeloid progenitor cells but promotes their proliferation in response to granulocyte-colony stimulating factor (G-CSF).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

The Wilms tumor suppressor WT1 directs stage-specific quiescence and differentiation of human hematopoietic progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Simultaneous expression of different immunogenic antigens in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Constitutive expression of the Wilms' tumor gene (WT1) in the leukemic cell line U937 blocks parts of the differentiation program

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Downregulation of Wilms' tumor gene (WT1) is not a prerequisite for erythroid or megakaryocytic differentiation of the leukemic cell line K562.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Overexpression of murine WT1 + / + and - / - isoforms has no effect on chemoresistance but delays differentiation in the K562 leukemia cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Ribozyme-mediated cleavage of wt1 transcripts suppresses growth of leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

p53 may mediate the mdr-1 expression via the WT1 gene in human vincristine-resistant leukemia/lymphoma cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Th2 and Tc2 cells in the regulation of GVHD, GVL, and graft rejection: considerations for the allogeneic transplantation therapy of leukemia and lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

CD8(+) minor histocompatibility antigen-specific cytotoxic T lymphocyte clones eliminate human acute myeloid leukemia stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Minor transplantation antigens: animal models for human host-versus-graft, graft-versus-host, and graft-versus-leukemia reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

A human minor histocompatibility antigen specific for B cell acute lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Identification of a novel WT1-derived peptide which induces human leucocyte antigen-A24-restricted anti-leukaemia cytotoxic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Alternative splicing and genomic structure of the Wilms tumor gene WT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Binding of the Wilms' tumor locus zinc finger protein to the EGR-1 consensus sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Transcriptional repression mediated by the WT1 Wilms tumor gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Abnormal WT1 expression in the CD34-negative compartment in myelodysplastic bone marrow

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Manipulation of T cell costimulatory and inhibitory signals for immunotherapy of prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Improved immunogenicity and protective efficacy of a tuberculosis DNA vaccine encoding Ag85 by protein boosting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Localization of CD4+ T cell epitope hotspots to exposed strands of HIV envelope glycoprotein suggests structural influences on antigen processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

DNA prime/canarypox boost-based immunotherapy of chronic hepatitis B virus infection in a chimpanzee

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Recombinant viruses as a tool for therapeutic vaccination against human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

The prime-boost strategy: exciting prospects for improved vaccination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Expression of the wt1 Wilms' tumor gene by normal and malignant human melanocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Early detection of relapse after bone marrow transplantation in patients with chronic myelogenous leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Applicability of an absolute quantitative procedure to monitor intra-individual bcr/abl transcript kinetics in clinical samples from chronic myelogenous leukemia patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

The Wilms tumor suppressor gene WT1 induces G1 arrest and apoptosis in myeloblastic leukemia M1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Early detection of BCR-ABL transcripts by quantitative reverse transcriptase-polymerase chain reaction predicts outcome after allogeneic stem cell transplantation for chronic myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

Has the prognosis of adult patients with acute myeloid leukemia improved over years? A single institution experience of 784 consecutive patients over a 16-year period

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Donor leukocyte infusions in 140 patients with relapsed malignancy after allogeneic bone marrow transplantation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

The role of immunotherapy in acute myelogenous leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Quantification of WT1 mRNA by competitive NASBA in AML patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Fluorescent 5'-exonuclease assay for the absolute quantification of Wilms' tumour gene (WT1) mRNA: implications for monitoring human leukaemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Prognostic significance of WT1 gene expression at diagnosis in adult de novo acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

The coexpression of the apoptosis-related genes bcl-2 and wt1 in predicting survival in adult acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Mutation analysis of the WT1 gene in sporadic childhood leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

wt1 gene expression in childhood leukemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

wt1 gene expression in childhood acute leukemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Real-time quantitative PCR detection of WT1 gene expression in children with AML: prognostic significance, correlation with disease status and residual disease detection by flow cytometry

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Wilms' tumour gene (wt1) expression at diagnosis has no prognostic relevance in childhood acute lymphoblastic leukaemia treated by an intensive chemotherapy protocol

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Quantitative assessment of WT1 expression by real time quantitative PCR may be a useful tool for monitoring minimal residual disease in acute leukemia patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Expression of Wilms tumor gene (WT1) in children with acute leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Detection of the WT1 transcript by RT-PCR in complete remission has no prognostic relevance in de novo acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

The Wilms' tumor gene WT1 is a good marker for diagnosis of disease progression of myelodysplastic syndromes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Mutation of the WT1 gene in myelodysplastic syndrome and acute myeloid leukaemia post myelodysplastic syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Mutation analysis of the WT1 gene in secondary leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

The Wilms' tumor gene is frequently expressed in acute myeloblastic leukemias and may provide a marker for residual blast cells detectable by PCR

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Detection by monoclonal antibodies of the Wilms' tumor (WT1) nuclear protein in patients with acute leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Very low frequencies of human normal CD34+ haematopoietic progenitor cells express the Wilms' tumour gene WT1 at levels similar to those in leukaemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Forced expression of the Wilms tumor 1 (WT1) gene inhibits proliferation of human hematopoietic CD34(+) progenitor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Suppression of Wilms' tumor gene (WT1) expression induces G2/M arrest in leukemic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Is there a graft-versus-leukaemia effect in the absence of graft-versus-host disease in patients undergoing bone marrow transplantation for acute leukaemia?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Human cytotoxic T-lymphocyte responses specific for peptides of the wild-type Wilms' tumor gene (WT1 ) product

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Cancer immunotherapy targeting Wilms' tumor gene WT1 product

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Humoral immune responses against Wilms tumor gene WT1 product in patients with hematopoietic malignancies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Cytotoxic T-lymphocyte responses elicited to Wilms' tumor gene WT1 product by DNA vaccination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Analysis of the 11p13 Wilms' tumor suppressor gene (WT1) in ovarian tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

WT1 is an integral component of an antibody panel to distinguish pancreaticobiliary and some ovarian epithelial neoplasms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Value of molecular monitoring during the treatment of chronic myeloid leukemia: a Cancer and Leukemia Group B study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Involvement and functional impairment of the CD34(+)CD38(-)Thy-1(+) hematopoietic stem cell pool in myelodysplastic syndromes with trisomy 8.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402988

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2402988

1 reference

6 August 2017

1 reference