Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling (Q35164256)

6 August 2017

title

Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling (English)

1 reference

6 August 2017

Megan T Baldridge

2

0 references

Sung Yun Jung

object named as

Sung Yun Jung

8

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Margaret A Goodell

object named as

Margaret A Goodell

14

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author name string

Katherine Y King

1

1 reference

6 August 2017

David C Weksberg

3

1 reference

6 August 2017

Stuart M Chambers

4

1 reference

6 August 2017

Georgi L Lukov

5

1 reference

6 August 2017

Shihua Wu

6

1 reference

6 August 2017

Nathan C Boles

7

1 reference

6 August 2017

Jun Qin

9

1 reference

6 August 2017

Dan Liu

10

1 reference

6 August 2017

Zhou Songyang

11

1 reference

6 August 2017

N Tony Eissa

12

1 reference

6 August 2017

Gregory A Taylor

13

1 reference

6 August 2017

language of work or name

English

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publication date

1 June 2011

1 reference

6 August 2017

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6 August 2017

volume

118

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6 August 2017

issue

6

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6 August 2017

page(s)

1525-1533

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The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance

6 August 2017

cites work

1 reference

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Polymorphic allele of human IRGM1 is associated with susceptibility to tuberculosis in African Americans

13 July 2018

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Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection

13 July 2018

1 reference

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Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1.

13 July 2018

1 reference

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Localisation and mislocalisation of the interferon-inducible immunity-related GTPase, Irgm1 (LRG-47) in mouse cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156044

Autophagy gene variant IRGM -261T contributes to protection from tuberculosis caused by Mycobacterium tuberculosis but not by M. africanum strains

13 July 2018

1 reference

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Targeting of the GTPase Irgm1 to the phagosomal membrane via PtdIns(3,4)P(2) and PtdIns(3,4,5)P(3) promotes immunity to mycobacteria

13 July 2018

1 reference

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Death and resurrection of the human IRGM gene

13 July 2018

1 reference

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Balance of Irgm protein activities determines IFN-gamma-induced host defense

13 July 2018

1 reference

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Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease

13 July 2018

1 reference

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ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling

13 July 2018

1 reference

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Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii

13 July 2018

1 reference

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Stem cell identification and sorting using the Hoechst 33342 side population (SP).

13 July 2018

1 reference

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The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation

13 July 2018

1 reference

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Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

13 July 2018

1 reference

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Control of IFN-gamma-mediated host resistance to intracellular pathogens by immunity-related GTPases (p47 GTPases).

13 July 2018

1 reference

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Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156044

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

13 July 2018

1 reference

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Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages

13 July 2018

1 reference

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Human IRGM induces autophagy to eliminate intracellular mycobacteria

13 July 2018

1 reference

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13 July 2018

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13 July 2018

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Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156044

Molecular signatures of proliferation and quiescence in hematopoietic stem cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156044

Mechanisms regulating the positioning of mouse p47 resistance GTPases LRG-47 and IIGP1 on cellular membranes: retargeting to plasma membrane induced by phagocytosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156044

Mice deficient in LRG-47 display increased susceptibility to mycobacterial infection associated with the induction of lymphopenia.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156044

In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker

13 July 2018

1 reference

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Immune Control of Tuberculosis by IFN-γ-Inducible LRG-47

13 July 2018

1 reference

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TNF-alpha and IFN-gamma are overexpressed in the bone marrow of Fanconi anemia patients and TNF-alpha suppresses erythropoiesis in vitro.

13 July 2018

1 reference

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Stem and progenitor cells: origins, phenotypes, lineage commitments, and transdifferentiations

13 July 2018

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Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156044

Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156044

Histone-like TAFs within the PCAF histone acetylase complex

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156044

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156044

Multiple defects of immune cell function in mice with disrupted interferon-gamma genes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156044

Demonstration of permanent factor-dependent multipotential (erythroid/neutrophil/basophil) hematopoietic progenitor cell lines

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156044

IFNalpha activates dormant haematopoietic stem cells in vivo.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156044

P-selectin suppresses hepatic inflammation and fibrosis in mice by regulating interferon gamma and the IL-13 decoy receptor

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156044

The gp49B1 inhibitory receptor regulates the IFN-gamma responses of T cells and NK cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156044

Immune response in mice that lack the interferon-gamma receptor

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21633090

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A mouse model of lymphocyte infusion-induced bone marrow failure

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21633090

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Clinical forms and outcome of tuberculosis in HIV-infected patients in a tertiary hospital in São Paulo - Brazil

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21633090

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2011-01-328682

1 reference

6 August 2017

1 reference

6 August 2017

1 reference