Differentially expressed miRNAs in Ewing sarcoma compared to mesenchymal stem cells: low miR-31 expression with effects on proliferation and invasion. (Q35131440)

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English	Differentially expressed miRNAs in Ewing sarcoma compared to mesenchymal stem cells: low miR-31 expression with effects on proliferation and invasion.	scientific article

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12 March 2020

Differentially expressed miRNAs in Ewing sarcoma compared to mesenchymal stem cells: low miR-31 expression with effects on proliferation and invasion (English)

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12 March 2020

mesenchymal stem cell

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12 March 2020

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Bianca Karnuth

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12 March 2020

Nicolas Dedy

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12 March 2020

Tilmann Spieker

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12 March 2020

Elizabeth R Lawlor

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12 March 2020

Stefan Gattenlöhner

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12 March 2020

Uta Dirksen

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12 March 2020

Heribert Jürgens

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12 March 2020

Andreas Bräuninger

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25 March 2014

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12 March 2020

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12 March 2020

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12 March 2020

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12 March 2020

e93067

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12 March 2020

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25 March 2014

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0 references

Tumor suppressive microRNAs (miR-222 and miR-31) regulate molecular pathways based on microRNA expression signature in prostate cancer.

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13 July 2018

Antagonism pattern detection between microRNA and target expression in Ewing's sarcoma

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13 July 2018

EWS/FLI1 regulates EYA3 in Ewing sarcoma via modulation of miRNA-708, resulting in increased cell survival and chemoresistance.

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13 July 2018

A TARBP2-dependent miRNA expression profile underlies cancer stem cell properties and provides candidate therapeutic reagents in Ewing sarcoma

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13 July 2018

An integrated analysis of miRNA and gene copy numbers in xenografts of Ewing's sarcoma

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MetastamiRs: non-coding MicroRNAs driving cancer invasion and metastasis

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13 July 2018

miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancy

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13 July 2018

Let-7a Is a Direct EWS-FLI-1 Target Implicated in Ewing's Sarcoma Development

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A novel oncogenic mechanism in Ewing sarcoma involving IGF pathway targeting by EWS/Fli1-regulated microRNAs

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Modeling initiation of Ewing sarcoma in human neural crest cells

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Downregulation of miR-205 and miR-31 confers resistance to chemotherapy-induced apoptosis in prostate cancer cells

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13 July 2018

Hsa-mir-145 is the top EWS-FLI1-repressed microRNA involved in a positive feedback loop in Ewing's sarcoma

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13 July 2018

Metastamirs: a stepping stone towards improved cancer management

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13 July 2018

Recent advances in the molecular pathogenesis of Ewing's sarcoma

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13 July 2018

Pro-tumorigenic effects of miR-31 loss in mesothelioma

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13 July 2018

EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965523

13 July 2018

Molecular profiling uncovers a p53-associated role for microRNA-31 in inhibiting the proliferation of serous ovarian carcinomas and other cancers

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Concomitant suppression of three target genes can explain the impact of a microRNA on metastasis

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Causes and consequences of microRNA dysregulation in cancer

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13 July 2018

A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis

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13 July 2018

EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation

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13 July 2018

MiRNA expression in urothelial carcinomas: important roles of miR-10a, miR-222, miR-125b, miR-7 and miR-452 for tumor stage and metastasis, and frequent homozygous losses of miR-31

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Most mammalian mRNAs are conserved targets of microRNAs

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13 July 2018

Changes in incidence and survival of Ewing sarcoma patients over the past 3 decades: Surveillance Epidemiology and End Results data.

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13 July 2018

Mesenchymal stem cell features of Ewing tumors

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13 July 2018

Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcoma

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Safety assessment of intensive induction with vincristine, ifosfamide, doxorubicin, and etoposide (VIDE) in the treatment of Ewing tumors in the EURO-E.W.I.N.G. 99 clinical trial

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Development of Ewing's sarcoma from primary bone marrow-derived mesenchymal progenitor cells

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Real-time quantification of microRNAs by stem-loop RT-PCR

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EWS/FLI-1 silencing and gene profiling of Ewing cells reveal downstream oncogenic pathways and a crucial role for repression of insulin-like growth factor binding protein 3.

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A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG

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Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

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Increased risk of systemic relapses associated with bone marrow micrometastasis and circulating tumor cells in localized ewing tumor.

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EWS-FLI-1 expression triggers a Ewing's sarcoma initiation program in primary human mesenchymal stem cells.

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The predictive potential of molecular detection in the nonmetastatic Ewing family of tumors

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EWS-FLI1 and EWS-ERG gene fusions are associated with similar clinical phenotypes in Ewing's sarcoma.

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Impact of EWS-ETS fusion type on disease progression in Ewing's sarcoma/peripheral primitive neuroectodermal tumor: prospective results from the cooperative Euro-E.W.I.N.G. 99 trial

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Risk of recurrence and survival after relapse in patients with Ewing sarcoma

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12 December 2020

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