Hedgehog/Ras interactions regulate early stages of pancreatic cancer (Q35127709)

6 August 2017

title

Hedgehog/Ras interactions regulate early stages of pancreatic cancer (English)

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6 August 2017

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Marina Pasca di Magliano

1

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6 August 2017

Shigeki Sekine

2

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6 August 2017

Alexandre Ermilov

3

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6 August 2017

Jenny Ferris

4

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6 August 2017

Andrzej A Dlugosz

5

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6 August 2017

Matthias Hebrok

6

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6 August 2017

publication date

1 November 2006

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6 August 2017

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6 August 2017

volume

20

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6 August 2017

issue

22

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6 August 2017

page(s)

3161-3173

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Notch signalling regulates stem cell numbers in vitro and in vivo

6 August 2017

cites work

1 reference

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N-cadherin and keratinocyte growth factor receptor mediate the functional interplay between Ki-RASG12V and p53V143A in promoting pancreatic cell migration, invasion, and tissue architecture disruption

28 July 2018

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28 July 2018

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28 July 2018

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A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2

28 July 2018

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Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

28 July 2018

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28 July 2018

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28 July 2018

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Notch signaling controls multiple steps of pancreatic differentiation

28 July 2018

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Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

28 July 2018

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28 July 2018

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Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors

28 July 2018

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Pancreatic intraepithelial neoplasia: a new nomenclature and classification system for pancreatic duct lesions

28 July 2018

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A murine tumor progression model for pancreatic cancer recapitulating the genetic alterations of the human disease

28 July 2018

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Notch gene expression during pancreatic organogenesis

28 July 2018

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Control of endodermal endocrine development by Hes-1

28 July 2018

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Notch signalling controls pancreatic cell differentiation

28 July 2018

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Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas

28 July 2018

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Tumor-suppressive pathways in pancreatic carcinoma.

28 July 2018

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28 July 2018

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K-ras mutations in pancreatic ductal proliferative lesions

28 July 2018

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Expression of p53 protein in precursor lesions and adenocarcinoma of human pancreas

28 July 2018

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Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes

28 July 2018

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Efficient selection for high-expression transfectants with a novel eukaryotic vector

28 July 2018

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Liver-specific loss of beta-catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in mice

28 July 2018

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Pten constrains centroacinar cell expansion and malignant transformation in the pancreas

27 September 2018

1 reference

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Hedgehog signaling regulates expansion of pancreatic epithelial cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635150

Notch inhibits Ptf1 function and acinar cell differentiation in developing mouse and zebrafish pancreas

27 September 2018

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Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma

27 September 2018

1 reference

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Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

27 September 2018

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Multicomponent analysis of the pancreatic adenocarcinoma progression model using a pancreatic intraepithelial neoplasia tissue microarray

27 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1635150

p16 and K-ras gene mutations in the intraductal precursors of human pancreatic adenocarcinoma

27 September 2018

1 reference

12 December 2020

Undifferentiated carcinoma of the pancreas: analysis of intermediate filament profile and Ki-ras mutations provides evidence of a ductal origin

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12 December 2020

Malignant transformation of duct-like cells originating from acini in transforming growth factor transgenic mice

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12 December 2020

Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: evidence that DPC4 inactivation occurs late in neoplastic progression

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12 December 2020

Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis

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12 December 2020

Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast

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12 December 2020

Identifiers

DOI

10.1101/GAD.1470806

1 reference

6 August 2017

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6 August 2017

1 reference