The emerging role of the thioredoxin system in angiogenesis (Q35123800)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20798378%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

The emerging role of the thioredoxin system in angiogenesis (English)

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12 February 2020

3

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12 February 2020

author name string

Louise L Dunn

series ordinal

1

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12 February 2020

Andrew M Buckle

series ordinal

2

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12 February 2020

Martin K C Ng

series ordinal

4

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12 February 2020

language of work or name

English

0 references

publication date

26 August 2010

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Arteriosclerosis, Thrombosis, and Vascular Biology

12 February 2020

published in

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12 February 2020

volume

30

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12 February 2020

issue

11

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12 February 2020

page(s)

2089-2098

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Thioredoxin-1 gene therapy enhances angiogenic signaling and reduces ventricular remodeling in infarcted myocardium of diabetic rats

12 February 2020

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Intracellular shuttling and mitochondrial function of thioredoxin-interacting protein

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The cyclin-dependent kinase inhibitor, p21(WAF1), promotes angiogenesis by repressing gene transcription of thioredoxin-binding protein 2 in cancer cells

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Modulation of thioredoxin reductase-2 expression in EAhy926 cells: implications for endothelial selenoprotein hierarchy

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Diabetes induces and calcium channel blockers prevent cardiac expression of proapoptotic thioredoxin-interacting protein

28 July 2018

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Endothelial-specific expression of mitochondrial thioredoxin promotes ischemia-mediated arteriogenesis and angiogenesis

28 July 2018

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AIP1 functions as an endogenous inhibitor of VEGFR2-mediated signaling and inflammatory angiogenesis in mice

28 July 2018

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Txnip balances metabolic and growth signaling via PTEN disulfide reduction

28 July 2018

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Rare sugar D-allose induces specific up-regulation of TXNIP and subsequent G1 cell cycle arrest in hepatocellular carcinoma cells by stabilization of p27kip1.

28 July 2018

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Thioredoxin-interacting protein: a critical link between glucose toxicity and beta-cell apoptosis

28 July 2018

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The mitochondrial thioredoxin system regulates nitric oxide-induced HIF-1alpha protein

28 July 2018

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Reactive oxygen species regulate angiogenesis and tumor growth through vascular endothelial growth factor

28 July 2018

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Regulation of the bioavailability of thioredoxin in the lens by a specific thioredoxin-binding protein (TBP-2).

28 July 2018

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Hyperglycemia regulates thioredoxin-ROS activity through induction of thioredoxin-interacting protein (TXNIP) in metastatic breast cancer-derived cells MDA-MB-231.

28 July 2018

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Inhibition of thioredoxin reductase by auranofin induces apoptosis in cisplatin-resistant human ovarian cancer cells.

28 July 2018

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An analysis of high glucose and glucosamine-induced gene expression and oxidative stress in renal mesangial cells

28 July 2018

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Thioredoxin and related molecules--from biology to health and disease

28 July 2018

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28 July 2018

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Intrinsic apoptotic and thioredoxin pathways in human prostate cancer cell response to histone deacetylase inhibitor

28 July 2018

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Nitric oxide-dependent suppression of thioredoxin-interacting protein expression enhances thioredoxin activity

28 July 2018

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Molecular pharmacology and antitumor activity of palmarumycin-based inhibitors of thioredoxin reductase

28 July 2018

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The antitumor thioredoxin-1 inhibitor PX-12 (1-methylpropyl 2-imidazolyl disulfide) decreases thioredoxin-1 and VEGF levels in cancer patient plasma

28 July 2018

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Thioredoxin reductase regulates the induction of haem oxygenase-1 expression in aortic endothelial cells

28 July 2018

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Catalytic degradation of vitamin D up-regulated protein 1 mRNA enhances cardiomyocyte survival and prevents left ventricular remodeling after myocardial ischemia

28 July 2018

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Gene expression profiling in INS-1 cells overexpressing thioredoxin-interacting protein

28 July 2018

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28 July 2018

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HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas.

28 July 2018

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28 July 2018

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28 July 2018

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Low doses of reactive oxygen species protect endothelial cells from apoptosis by increasing thioredoxin-1 expression

28 July 2018

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Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart function

28 July 2018

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Thioredoxin modulates activator protein 1 (AP-1) activity and p27Kip1 degradation through direct interaction with Jab1

28 July 2018

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Importin alpha1 (Rch1) mediates nuclear translocation of thioredoxin-binding protein-2/vitamin D(3)-up-regulated protein 1

28 July 2018

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Hyperglycemia promotes oxidative stress through inhibition of thioredoxin function by thioredoxin-interacting protein

28 July 2018

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Mitochondrial thioredoxin system: effects of TrxR2 overexpression on redox balance, cell growth, and apoptosis

28 July 2018

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28 July 2018

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The thioredoxin redox inhibitors 1-methylpropyl 2-imidazolyl disulfide and pleurotin inhibit hypoxia-induced factor 1alpha and vascular endothelial growth factor formation.

28 July 2018

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Melanoma metastasis suppression by chromosome 6: evidence for a pathway regulated by CRSP3 and TXNIP

28 July 2018

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Vitamin D3-upregulated protein-1 (VDUP-1) regulates redox-dependent vascular smooth muscle cell proliferation through interaction with thioredoxin

28 July 2018

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Redox regulatory and anti-apoptotic functions of thioredoxin depend on S-nitrosylation at cysteine 69.

28 July 2018

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Thioredoxin promotes ASK1 ubiquitination and degradation to inhibit ASK1-mediated apoptosis in a redox activity-independent manner

28 July 2018

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Vitamin D(3)-up-regulated protein-1 is a stress-responsive gene that regulates cardiomyocyte viability through interaction with thioredoxin

28 July 2018

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28 July 2018

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Up-regulation of thioredoxin and thioredoxin reductase in human malignant pleural mesothelioma

28 July 2018

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Vitamin D3 up-regulated protein 1 mediates oxidative stress via suppressing the thioredoxin function

28 July 2018

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28 July 2018

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Redox-regulated recruitment of the transcriptional coactivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1alpha

28 July 2018

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Vascular endothelial growth factor and diabetes: the agonist versus antagonist paradox

28 July 2018

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Distinct roles of thioredoxin in the cytoplasm and in the nucleus. A two-step mechanism of redox regulation of transcription factor NF-kappaB.

28 July 2018

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NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

28 July 2018

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NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

28 July 2018

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Identification of thioredoxin-binding protein-2/vitamin D(3) up-regulated protein 1 as a negative regulator of thioredoxin function and expression

28 July 2018

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Overexpression of thioredoxin in transgenic mice attenuates focal ischemic brain damage

28 July 2018

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Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

28 July 2018

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Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factor-induced angiogenesis

28 July 2018

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AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1

28 July 2018

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Transfection with human thioredoxin increases cell proliferation and a dominant-negative mutant thioredoxin reverses the transformed phenotype of human breast cancer cells

28 July 2018

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Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

28 July 2018

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Low levels of reactive oxygen species as modulators of cell function

28 July 2018

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Upregulation of vascular endothelial growth factor expression induced by myocardial ischaemia: implications for coronary angiogenesis

28 July 2018

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A thioredoxin--thioredoxin reductase system from rat tumor.

28 July 2018

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Inhibition of human endothelial cell proliferation by gold compounds

28 July 2018

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Epstein-Barr virus-containing B-cell line produces an interleukin 1 that it uses as a growth factor

28 July 2018

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Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity

28 July 2018

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Thioredoxin regulates the DNA binding activity of NF-kappa B by reduction of a disulphide bond involving cysteine 62

28 July 2018

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Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme

28 July 2018

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Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

28 July 2018

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A gold(I) phosphine complex containing a naphthalimide ligand functions as a TrxR inhibiting antiproliferative agent and angiogenesis inhibitor.

28 July 2018

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Lack of TXNIP protects beta-cells against glucotoxicity

27 September 2018

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hnRNP G elicits tumor-suppressive activity in part by upregulating the expression of Txnip

27 September 2018

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Thioredoxin-interacting protein (Txnip) is a critical regulator of hepatic glucose production

27 September 2018

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Targeted deletion of thioredoxin-interacting protein regulates cardiac dysfunction in response to pressure overload

27 September 2018

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Endothelial-specific expression of mitochondrial thioredoxin improves endothelial cell function and reduces atherosclerotic lesions

27 September 2018

1 reference

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Thioredoxin 1 and thioredoxin 2 have opposed regulatory functions on hypoxia-inducible factor-1alpha

27 September 2018

1 reference

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A central role for nicotinic cholinergic regulation of growth factor-induced endothelial cell migration.

27 September 2018

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The interaction of thioredoxin with Txnip. Evidence for formation of a mixed disulfide by disulfide exchange

27 September 2018

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Hepatocellular carcinoma in Txnip-deficient mice.

27 September 2018

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Antioxidant enzymes in oligodendroglial brain tumors: association with proliferation, apoptotic activity and survival

27 September 2018

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Impaired fatty acid utilization in thioredoxin binding protein-2 (TBP-2)-deficient mice: a unique animal model of Reye syndrome

27 September 2018

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Resveratrol enhances neovascularization in the infarcted rat myocardium through the induction of thioredoxin-1, heme oxygenase-1 and vascular endothelial growth factor

27 September 2018

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Two distinct mechanisms for loss of thioredoxin-binding protein-2 in oxidative stress-induced renal carcinogenesis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142174

Antisense-thioredoxin inhibits angiogenesis via pVHL-mediated hypoxia-inducible factor-1alpha degradation.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142174

Thioredoxin-interacting protein is stimulated by glucose through a carbohydrate response element and induces beta-cell apoptosis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142174

Fluid shear stress inhibits vascular inflammation by decreasing thioredoxin-interacting protein in endothelial cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142174

Thioredoxin reductase regulates angiogenesis by increasing endothelial cell-derived vascular endothelial growth factor

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142174

Downregulation of metastasis suppressor genes in malignant pheochromocytoma.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142174

Increased lipogenesis and fatty acid reesterification contribute to hepatic triacylglycerol stores in hyperlipidemic Txnip-/- mice

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142174

Mice lacking thioredoxin-interacting protein provide evidence linking cellular redox state to appropriate response to nutritional signals

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142174

Shear stress increases the amount of S-nitrosylated molecules in endothelial cells: important role for signal transduction

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142174

Increased expression of thioredoxin-1 in human colorectal cancer is associated with decreased patient survival

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142174

AIP1 mediates TNF-alpha-induced ASK1 activation by facilitating dissociation of ASK1 from its inhibitor 14-3-3

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142174

Vitamin D3 up-regulated protein 1 (VDUP1) expression in gastrointestinal cancer and its relation to stage of disease.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142174

The absence of mitochondrial thioredoxin 2 causes massive apoptosis, exencephaly, and early embryonic lethality in homozygous mice

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142174

Overexpression of thioredoxin-1 in transgenic mice attenuates adriamycin-induced cardiotoxicity

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142174

The redox protein thioredoxin-1 (Trx-1) increases hypoxia-inducible factor 1alpha protein expression: Trx-1 overexpression results in increased vascular endothelial growth factor production and enhanced tumor angiogenesis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142174

Oligonucleotide microarray analysis of intact human pancreatic islets: identification of glucose-responsive genes and a highly regulated TGFbeta signaling pathway

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142174

The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142174

Thioredoxin expression in primary T-cell acute lymphoblastic leukemia and its therapeutic implication.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142174

Overexpression of p27(Kip1) by doxycycline-regulated adenoviral vectors inhibits endothelial cell proliferation and migration and impairs angiogenesis.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142174

Endothelial dysfunction in diabetes mellitus

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142174

Thioredoxin redox control of cell growth and death and the effects of inhibitors

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142174

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142174

Mammalian peroxiredoxin isoforms can reduce hydrogen peroxide generated in response to growth factors and tumor necrosis factor-alpha.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142174

Early embryonic lethality caused by targeted disruption of the mouse thioredoxin gene.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142174

Important Role of Apoptosis Signal-Regulating Kinase 1 in Ischemia-Induced Angiogenesis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142174

Thioredoxin expression is associated with lymph node status and prognosis in early operable non-small cell lung cancer

16 November 2018

1 reference

12 December 2020

Selenium-induced inhibition of angiogenesis in mammary cancer at chemopreventive levels of intake

1 reference

12 December 2020

Identification of molecules involved in the 'early pregnancy factor' phenomenon

1 reference

12 December 2020

ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEOTIDES. IV. ISOLATION AND CHARACTERIZATION OF THIOREDOXIN, THE HYDROGEN DONOR FROM ESCHERICHIA COLI B

1 reference

12 December 2020

Biphasic regulation of angiogenesis by reactive oxygen species

1 reference

12 December 2020

Increased expression of thioredoxin-1, vascular endothelial growth factor, and redox factor-1 is associated with poor prognosis in patients with liver metastasis from colorectal cancer

1 reference

12 December 2020

10.1161/ATVBAHA.110.209643

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20798378%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20798378%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

PubMed publication ID

20798378

1 reference