HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells (Q35102340)

6 August 2017

title

HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells (English)

1 reference

6 August 2017

Hongbo Chi

7

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Peter Vogel

object named as

Peter Vogel

4

0 references

Douglas R. Green

object named as

Douglas R Green

6

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author name string

Lewis Z Shi

1

1 reference

6 August 2017

Ruoning Wang

2

1 reference

6 August 2017

Gonghua Huang

3

1 reference

6 August 2017

Geoffrey Neale

5

1 reference

6 August 2017

language of work or name

English

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publication date

27 June 2011

1 reference

Journal of Experimental Medicine

6 August 2017

published in

1 reference

6 August 2017

volume

208

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6 August 2017

issue

7

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6 August 2017

page(s)

1367-1376

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Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.

6 August 2017

cites work

1 reference

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9 July 2018

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The S1P(1)-mTOR axis directs the reciprocal differentiation of T(H)1 and T(reg) cells.

9 July 2018

1 reference

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Activation of a metabolic gene regulatory network downstream of mTOR complex 1

9 July 2018

1 reference

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Th17 and regulatory T cells in mediating and restraining inflammation

9 July 2018

1 reference

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Astrocyte-restricted ablation of interleukin-17-induced Act1-mediated signaling ameliorates autoimmune encephalomyelitis

9 July 2018

1 reference

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Differentiation of effector CD4 T cell populations (*)

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135370

Metabolism in T cell activation and differentiation

9 July 2018

1 reference

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Anergic T cells are metabolically anergic

9 July 2018

1 reference

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Interdependence of hypoxic and innate immune responses

9 July 2018

1 reference

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Infectious tolerance via the consumption of essential amino acids and mTOR signaling

9 July 2018

1 reference

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mTOR regulates memory CD8 T-cell differentiation

9 July 2018

1 reference

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The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment

9 July 2018

1 reference

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Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response

9 July 2018

1 reference

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Enhancing CD8 T-cell memory by modulating fatty acid metabolism

9 July 2018

1 reference

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The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR.

9 July 2018

1 reference

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The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo

9 July 2018

1 reference

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Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

9 July 2018

1 reference

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Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells

9 July 2018

1 reference

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Integration of metabolism and inflammation by lipid-activated nuclear receptors

9 July 2018

1 reference

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LXR signaling couples sterol metabolism to proliferation in the acquired immune response.

9 July 2018

1 reference

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T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.

9 July 2018

1 reference

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NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha

9 July 2018

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TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

9 July 2018

1 reference

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The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135370

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135370

Hypoxia inducible factor 1 alpha regulates T cell receptor signal transduction.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135370

Fuel feeds function: energy metabolism and the T-cell response

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135370

On the Origin of Cancer Cells

9 July 2018

1 reference

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Hypoxia-inducible factor-1alpha is a positive factor in solid tumor growth.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135370

Difference in glucose sensitivity of liver glycolysis and glycogen synthesis. Relationship between lactate production and fructose 2,6-bisphosphate concentration

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135370

Hypoxia controls CD4+CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1alpha

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135370

Revving the engine: signal transduction fuels T cell activation

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135370

Cutting edge: regulation of T cell trafficking and primary immune responses by sphingosine 1-phosphate receptor 1.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135370

Cutting edge: hypoxia-inducible factor 1alpha and its activation-inducible short isoform I.1 negatively regulate functions of CD4+ and CD8+ T lymphocytes

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21708926

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20110278

1 reference

6 August 2017

1 reference

6 August 2017

1 reference