Evidence for a Role of Oxidative Stress in the Carcinogenicity of Ochratoxin A (Q35101972)

6 August 2017

1 reference

title

Evidence for a role of oxidative stress in the carcinogenicity of ochratoxin a (English)

1 reference

6 August 2017

Evidence for a Role of Oxidative Stress in the Carcinogenicity of Ochratoxin A (English)

1 reference

7 December 2024

author name string

M. Marin-Kuan

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21776264

7 December 2024

V. Ehrlich

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21776264

7 December 2024

T. Delatour

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21776264

7 December 2024

C. Cavin

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21776264

7 December 2024

B. Schilter

5

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7 December 2024

language of work or name

English

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21776264

7 December 2024

publication date

22 June 2011

1 reference

full work available at URL

6 August 2017

http://downloads.hindawi.com/journals/jt/2011/645361.pdf

file format

Portable Document Format

online access status

open access

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21776264

https://europepmc.org/articles/PMC3135259

7 December 2024

file format

HyperText Markup Language

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21776264

https://europepmc.org/articles/PMC3135259?pdf=render

7 December 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21776264

http://downloads.hindawi.com/journals/jt/2011/645361.xml

7 December 2024

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7 December 2024

published in

Journal of toxicology

1 reference

6 August 2017

volume

2011

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6 August 2017

page(s)

645361

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Creative Commons Attribution 3.0 Unported

6 August 2017

copyright license

start time

1 January 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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April 2022 Public Data File from Crossref

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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The role of oxidative stress in carcinogenesis

9 July 2018

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Nitrosative stress and transcription

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9 July 2018

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9 July 2018

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The role of oxidative stress in the ochratoxin A-mediated toxicity in proximal tubular cells

9 July 2018

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Genotoxic effects of ochratoxin A in human-derived hepatoma (HepG2) cells

9 July 2018

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Comparing nitrosative versus oxidative stress toward zinc finger-dependent transcription. Unique role for NO.

9 July 2018

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Determination of the epigenetic effects of ochratoxin in a human kidney and a rat liver epithelial cell line

9 July 2018

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Epigenetic mechanisms of chemical carcinogenesis

9 July 2018

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Importance of oxidatively modified proteins in chronic renal failure

9 July 2018

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Nitrosation and oxidation in the regulation of gene expression

9 July 2018

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Ochratoxin A induces JNK activation and apoptosis in MDCK-C7 cells at nanomolar concentrations.

9 July 2018

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The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin

9 July 2018

1 reference

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Nephritogenic ochratoxin A interferes with hormonal signalling in immortalized human kidney epithelial cells

9 July 2018

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Gene expression and the thiol redox state

9 July 2018

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9 July 2018

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Epigenetic toxicology as toxicant-induced changes in intracellular signalling leading to altered gap junctional intercellular communication

9 July 2018

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The role of oxidative stress in chemical carcinogenesis

9 July 2018

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Cell-cell communication in carcinogenesis

9 July 2018

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Induction of free radicals in hepatocytes, mitochondria and microsomes of rats by ochratoxin A and its analogs

9 July 2018

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Carcinogenicity and kinetic aspects of ochratoxin A.

9 July 2018

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9 July 2018

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9 July 2018

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Gap junctional intercellular communication and cell proliferation during rat liver carcinogenesis

9 July 2018

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Alterations in calcium homeostasis as a possible cause of ochratoxin A nephrotoxicity

9 July 2018

1 reference

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Alterations in ATP-dependent calcium uptake by rat renal cortex microsomes following ochratoxin A administration in vivo or addition in vitro

9 July 2018

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Studies on some feed additives and materials giving partial protection against the suppressive effect of ochratoxin A on egg production of laying hens

9 July 2018

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Immunohistochemical analysis of 8-nitroguanine, a nitrative DNA lesion, in relation to inflammation-associated carcinogenesis

27 September 2018

1 reference

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Inula crithmoides extract protects against ochratoxin A-induced oxidative stress, clastogenic and mutagenic alterations in male rats.

27 September 2018

1 reference

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Effect of ochratoxin A on redox-regulated transcription factors, antioxidant enzymes and glutathione-S-transferase in cultured kidney tubulus cells

27 September 2018

1 reference

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Gene expression changes induced by ochratoxin A in renal and hepatic tissues of male F344 rat after oral repeated administration.

27 September 2018

1 reference

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Role of environmental toxins in endemic (Balkan) nephropathy. October 2006, Zagreb, Croatia

27 September 2018

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Protective effect of cyanidin 3-O-beta-D-glucoside on ochratoxin A-mediated damage in the rat.

27 September 2018

1 reference

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Carcinogen-specific gene expression profiles in short-term treated Eker and wild-type rats indicative of pathways involved in renal tumorigenesis.

27 September 2018

1 reference

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Adult hippocampal neural stem/progenitor cells in vitro are vulnerable to the mycotoxin ochratoxin-A.

27 September 2018

1 reference

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DNA damage by ochratoxin A in rat kidney assessed by the alkaline comet assay

27 September 2018

1 reference

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Early cytotoxic effects of ochratoxin A in rat liver: a morphological, biochemical and molecular study

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

The effect of ochratoxin A on the concentration of protein carbonyls in rats

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

Further arguments in favour of direct covalent binding of Ochratoxin A (OTA) after metabolic biotransformation

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

Ochratoxin A induces oxidative DNA damage in liver and kidney after oral dosing to rats.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

A toxicogenomics approach to identify new plausible epigenetic mechanisms of ochratoxin a carcinogenicity in rat.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

Alterations induced in vitro by ochratoxin A in rat lymphoid cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

Acute neurotoxic effects of the fungal metabolite ochratoxin-A.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

Ochratoxin a causes DNA damage and cytogenetic effects but no DNA adducts in rats.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

Unusual astrocyte reactivity caused by the food mycotoxin ochratoxin A in aggregating rat brain cell cultures

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

Melatonin counteracts oxidative stress in rats fed an ochratoxin A contaminated diet

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

Ochratoxin A-induced DNA damage in human fibroblast: protective effect of cyanidin 3-O-beta-d-glucoside.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

Proximal tubular toxicity of ochratoxin A is amplified by simultaneous inhibition of the extracellular signal-regulated kinases 1/2.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

Evidence for covalent DNA adduction by ochratoxin A following chronic exposure to rat and subacute exposure to pig.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

Hepatic disposition and effects of nitric oxide donors: rapid and concentration-dependent reduction in the cytochrome P450-mediated drug metabolism in isolated perfused rat livers

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

Ochratoxin A: lack of formation of covalent DNA adducts.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

Apoptosis and oxidative stress induced by ochratoxin A in rat kidney.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

Lack of effects of sodium 2-mercaptoethane sulfonate (mesna) on Ochratoxin A induced renal tumorigenicity following life-time oral administration of Ochratoxin A in DA and Lewis rats

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

A new approach to studying ochratoxin A (OTA)-induced nephrotoxicity: expression profiling in vivo and in vitro employing cDNA microarrays

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

Protein carbonyl groups as biomarkers of oxidative stress.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

Detection and characterization of a glutathione conjugate of ochratoxin A.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

Thioredoxin reductase regulates AP-1 activity as well as thioredoxin nuclear localization via active cysteines in response to ionizing radiation

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

Contribution of hepatocyte nuclear factor-4 to down-regulation of CYP2D6 gene expression by nitric oxide

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

Oxidative damage and stress response from ochratoxin a exposure in rats

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

Disruption of gap junctional intercellular communication in human renal cancer cell lines.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

Protection by indomethacin and aspirin against genotoxicity of ochratoxin A, particularly in the urinary bladder and kidney.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

Toxicity of ochratoxin A, its opened lactone form and several of its analogs: structure-activity relationships.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135259

Improving education and resources for health care providers

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2011%2F645361

Evidence of a new dechlorinated ochratoxin A derivative formed in opossum kidney cell cultures after pretreatment by modulators of glutathione pathways: Correlation with DNA-adduct formation

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2011%2F645361

Balkan endemic nephropathy, the haematopoietic system and the environmental connection

21 January 2018

1 reference

12 December 2020

Effect of superoxide dismutase and catalase on the nephrotoxicity induced by subchronical administration of ochratoxin A in rats

1 reference

12 December 2020

Retinol, ascorbic acid and alpha-tocopherol prevent DNA adduct formation in mice treated with the mycotoxins ochratoxin A and zearalenone

1 reference

12 December 2020

Structures of covalent adducts between DNA and ochratoxin a: a new factor in debate about genotoxicity and human risk assessment

1 reference

12 December 2020

Lipid peroxidation as a possible cause of ochratoxin A toxicity

1 reference

12 December 2020

Ochratoxin A: 13-week oral toxicity and cell proliferation in male F344/n rats

1 reference

12 December 2020

Expression of COX-2 and hsp72 in peritoneal macrophages after an acute ochratoxin A treatment in mice

1 reference

12 December 2020

The involvement of oxidative stress in ochratoxin A and fumonisin B1 toxicity in rats

1 reference

12 December 2020

Protective role of melatonin and coenzyme Q10 in ochratoxin A toxicity in rat liver and kidney

1 reference

12 December 2020

Standard and Fpg-modified comet assay in kidney cells of ochratoxin A- and fumonisin B(1)-treated rats

1 reference

12 December 2020

Abstracts of an International Symposium on Recent Advances in Endemic Nephropathy: The Role of Toxins in an Environmental Disease

1 reference

12 December 2020

Minimum tolerable exposure period and maximum threshold dietary intake of ochratoxin A for causing renal cancer in male Dark Agouti rats

1 reference

12 December 2020

Inhibition of AP-1 DNA binding by nitric oxide involving conserved cysteine residues in Jun and Fos

1 reference

12 December 2020

Evaluation of certain food additives and contaminants. Thirty-seventh report of the Joint FAO/WHO Expert Committee on Food Additives

1 reference

12 December 2020

Hemodialysis and protein oxidation products

1 reference

12 December 2020

Oxidation of ochratoxin A by an Fe-porphyrin system: model for enzymatic activation and DNA cleavage

1 reference

12 December 2020

Roles of cyclooxygenase and lipoxygenases in ochratoxin A genotoxicity in human epithelial lung cells

1 reference

12 December 2020

Evaluation of certain food additives and contaminants

1 reference

12 December 2020

Perturbation of liver microsomal calcium homeostasis by ochratoxin A

1 reference

12 December 2020

Mechanism of ochratoxin A stimulated lipid peroxidation

1 reference

12 December 2020

Ochratoxin A in food: recent developments and significance

3

1 reference

Molecular Cancer Therapeutics

7 December 2024

46

2

815

2003

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Journal of Pharmacology and Experimental Therapeutics

7 December 2024

79

293

837

2000

1 reference

7 December 2024

Medical Science Monitor

85

8

RA217

2002

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Facta Universitatis Series Medicine and Biology

7 December 2024

116

9

57

2002

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7 December 2024

Identifiers

DOI

10.1155/2011/645361

1 reference

6 August 2017

1 reference

6 August 2017

1 reference