Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders (Q35068082)

6 August 2017

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title

Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders (English)

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6 August 2017

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Mark P Mattson

1

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6 August 2017

Thomas B Shea

series ordinal

2

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6 August 2017

publication date

1 March 2003

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6 August 2017

published in

Trends in Neurosciences

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6 August 2017

volume

26

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6 August 2017

issue

3

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6 August 2017

page(s)

137-146

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Folate-vitamin B12 interrelationships in the central nervous system

6 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Multiple aspects of homocysteine neurotoxicity: glutamate excitotoxicity, kinase hyperactivation and DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

The quantitatively important relationship between homocysteine metabolism and glutathione synthesis by the transsulfuration pathway and its regulation by redox changes

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

The metabolism of homocysteine: pathways and regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Apolipoprotein E deficiency promotes increased oxidative stress and compensatory increases in antioxidants in brain tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Carrier-mediated membrane transport of folates in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Vitamin deficiencies and neural tube defects

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Folate status: effects on pathways of colorectal carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Relationship between total homocysteine and folate levels in pregnant women and their newborn babies according to maternal serum levels of vitamin B12.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Function of vitamin B12 in the central nervous system as revealed by congenital defects

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Retardation of myelination due to dietary vitamin B12 deficiency: cranial MRI findings

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Neurological involvement in hereditary transcobalamin II deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Prenatal folic acid treatment suppresses acrania and meroanencephaly in mice mutant for the Cart1 homeobox gene

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Maternal genetic effects, exerted by genes involved in homocysteine remethylation, influence the risk of spina bifida

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Glutamate carboxypeptidase II: a polymorphism associated with lower levels of serum folate and hyperhomocysteinemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Reduced vitamin B12 binding by transcobalamin II increases the risk of neural tube defects

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Apoptotic and anti-apoptotic synaptic signaling mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Single-channel currents of NMDA type activated by L- and D-homocysteic acid in cerebellar granule cells in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Homocysteic and homocysteine sulphinic acid exhibit excitotoxicity in organotypic cultures from rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Folic acid has a disinhibitory action in the rat hippocampal slice preparation

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

The "thermolabile" variant of methylenetetrahydrofolate reductase and neural tube defects: An evaluation of genetic risk and the relative importance of the genotypes of the embryo and the mother.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Symptomatic and asymptomatic methylenetetrahydrofolate reductase deficiency in two adult brothers

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Functional methionine synthase deficiency (cblE and cblG): clinical and biochemical heterogeneity

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Homocysteine potentiates beta-amyloid neurotoxicity: role of oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Cerebrospinal Fluid and Plasma Total Homocysteine and Related Metabolites in Children with Cystathionine β-Synthase Deficiency: The Effect of Treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Abnormal folate metabolism and genetic polymorphism of the folate pathway in a child with Down syndrome and neural tube defect.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Abnormal folate metabolism and mutation in the methylenetetrahydrofolate reductase gene may be maternal risk factors for Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Homocysteine metabolism in children with Down syndrome: in vitro modulation

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Strategies for the treatment of cystathionine beta-synthase deficiency: the experience of the Willink Biochemical Genetics Unit over the past 30 years

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Long term treatment with betaine in methylenetetrahydrofolate reductase deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

An open-label, 24-week pilot study of the methyl donor betaine in Alzheimer disease patients

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

An Ultrastructural Study of Subacute Combined Degeneration of the Spinal Cord in Vitamin B12-Deficient Rhesus Monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Pathogenesis of subacute combined degeneration: a result of methyl group deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

The pathogenesis of homocysteinemia: interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Energy thresholds in brain mitochondria. Potential involvement in neurodegeneration.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Cellular and molecular mechanisms underlying perturbed energy metabolism and neuronal degeneration in Alzheimer's and Parkinson's diseases.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Bioenergetics in Huntington's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Folate depletion and elevated plasma homocysteine promote oxidative stress in rat livers

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Homocyst(e)ine decreases bioavailable nitric oxide by a mechanism involving glutathione peroxidase

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Vitamins C, E and A and heme oxygenase in rats fed methyl/folate-deficient diets

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Effects of vitamin C and vitamin E on in vivo lipid peroxidation: results of a randomized controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Folate quenches oxidative damage in brains of apolipoprotein E-deficient mice: augmentation by vitamin E.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Folate improves endothelial function in coronary artery disease: an effect mediated by reduction of intracellular superoxide?

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Homocysteine and stroke

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Plasma homocysteine as a risk factor for dementia and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Early diagnosis of cognitive impairment in the elderly with the focus on Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Total serum homocysteine in senile dementia of Alzheimer type

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Is metabolic evidence for vitamin B-12 and folate deficiency more frequent in elderly patients with Alzheimer's disease?

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Identification of cognitive impairment in the elderly: homocysteine is an early marker

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Serum folate and the severity of atrophy of the neocortex in Alzheimer disease: findings from the Nun study

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

CSF-folate levels are decreased in late-onset AD patients

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Cerebrospinal fluid S-adenosylmethionine in depression and dementia: effects of treatment with parenteral and oral S-adenosylmethionine

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Incorporating biomarkers into clinical drug trials in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Homocysteine potentiates copper- and amyloid beta peptide-mediated toxicity in primary neuronal cultures: possible risk factors in the Alzheimer's-type neurodegenerative pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Is hyperhomocysteinemia due to the oxidative depletion of folate rather than to insufficient dietary intake?

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Functional vitamin B(12) deficiency and Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Endoplasmic reticulum stress-inducible protein, Herp, enhances presenilin-mediated generation of amyloid beta-protein

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Brain hydrogen sulfide is severely decreased in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Brain S-adenosylmethionine levels are severely decreased in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Oxidative damage and protection by antioxidants in the frontal cortex of Alzheimer's disease is related to the apolipoprotein E genotype

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

A mechanism for the neuroprotective effect of apolipoprotein E: isoform-specific modification by the lipid peroxidation product 4-hydroxynonenal

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Apolipoprotein E, methylenetetrahydrofolate reductase (MTHFR) mutation and the risk of senile dementia--an epidemiological study using the polymerase chain reaction (PCR) method

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Intracellular generation of free radicals and modifications of detoxifying enzymes in cultured neurons from the developing rat forebrain in response to transient hypoxia

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Plasma homocysteine and MTHFR C677T genotype in levodopa-treated patients with PD

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Effects of L-dopa treatment on methylation in mouse brain: implications for the side effects of L-dopa

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Dietary folate deficiency and elevated homocysteine levels endanger dopaminergic neurons in models of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Nutrition and depression: focus on folate

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Homocysteine, folate, methylation, and monoamine metabolism in depression

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Effect of folic acid and vitamin B12 deficiencies on 5-hydroxyindoleacetic acid in human cerebrspinal fluid

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Schizophrenia and impaired homocysteine metabolism: a possible association

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Homocysteinemia is a common feature of schizophrenia

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Enhancement of recovery from psychiatric illness by methylfolate.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Homozygous thermolabile methylenetetrahydrofolate reductase in schizophrenia-like psychosis

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

Folic acid and B12 in autism and neuropsychiatric disturbances of childhood

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2803%2900032-8

7 January 2021

10.1016/S0166-2236(03)00032-8

Identifiers

DOI

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6 August 2017

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