The cancer gene WWOX behaves as an inhibitor of SMAD3 transcriptional activity via direct binding (Q35065263)

6 August 2017

0 references

The cancer gene WWOX behaves as an inhibitor of SMAD3 transcriptional activity via direct binding (English)

1 reference

6 August 2017

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24330518%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

C M Aldaz

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24330518%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

author name string

Brent W Ferguson

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24330518%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Xinsheng Gao

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24330518%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Maciej J Zelazowski

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24330518%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Jaeho Lee

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24330518%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Collene R Jeter

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24330518%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

language of work or name

English

0 references

publication date

11 December 2013

1 reference

6 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24330518%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24330518%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

page(s)

593

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24330518%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

11 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3871008/fullTextXML

inferred from PubMed Central ID database lookup

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/3871008

inferred from PubMed Central ID database lookup

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8 July 2018

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8 July 2018

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8 July 2018

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A Smad action turnover switch operated by WW domain readers of a phosphoserine code

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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WWOX gene and gene product: tumor suppression through specific protein interactions

8 July 2018

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Generation and characterization of mice carrying a conditional allele of the Wwox tumor suppressor gene

8 July 2018

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15-hydroxyeicosatetraenoic acid is a preferential peroxisome proliferator-activated receptor beta/delta agonist

8 July 2018

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Genes that mediate breast cancer metastasis to the brain

8 July 2018

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Transforming growth factor-beta in breast cancer: too much, too late

8 July 2018

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Fragile histidine triad protein, WW domain-containing oxidoreductase protein Wwox, and activator protein 2gamma expression levels correlate with basal phenotype in breast cancer

8 July 2018

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Roles of TGFbeta in metastasis

8 July 2018

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The WWOX tumor suppressor is essential for postnatal survival and normal bone metabolism

8 July 2018

1 reference

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Role of the WWOX gene, encompassing fragile region FRA16D, in suppression of pancreatic carcinoma cells.

8 July 2018

1 reference

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TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4

8 July 2018

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Association of Wwox with ErbB4 in breast cancer.

8 July 2018

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WWOX in biological control and tumorigenesis

8 July 2018

1 reference

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Targeted deletion of Wwox reveals a tumor suppressor function

8 July 2018

1 reference

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WWOX, a chromosomal fragile site gene and its role in cancer

8 July 2018

2 references

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8 July 2018

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A role for the WWOX gene in prostate cancer

21 January 2018

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Frequent loss of WWOX expression in breast cancer: correlation with estrogen receptor status

8 July 2018

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Rank products: a simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments

8 July 2018

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Smad3 interacts with JunB and Cbfa1/Runx2 for transforming growth factor-beta1-stimulated collagenase-3 expression in human breast cancer cells

8 July 2018

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The fragile genes FHIT and WWOX are inactivated coordinately in invasive breast carcinoma

8 July 2018

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WWOX binds the specific proline-rich ligand PPXY: identification of candidate interacting proteins

8 July 2018

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Venn Mapping: clustering of heterologous microarray data based on the number of co-occurring differentially expressed genes

8 July 2018

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8 July 2018

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E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression

8 July 2018

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Direct interaction of c-Myc with Smad2 and Smad3 to inhibit TGF-beta-mediated induction of the CDK inhibitor p15(Ink4B)

8 July 2018

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WWOX, the FRA16D gene, behaves as a suppressor of tumor growth

8 July 2018

1 reference

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Chromosome translocations in multiple myeloma

8 July 2018

1 reference

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WWOX: a candidate tumor suppressor gene involved in multiple tumor types

8 July 2018

1 reference

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NeW wrinkles for an old domain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871008

Role of Smad proteins and transcription factor Sp1 in p21(Waf1/Cip1) regulation by transforming growth factor-beta.

8 July 2018

1 reference

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Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871008

WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871008

Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871008

Reversible inhibition of mammary gland growth by transforming growth factor-beta

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871008

TGF beta signals through a heteromeric protein kinase receptor complex

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3871008

Urokinase (uPA) and its inhibitor PAI-1 are strong and independent prognostic factors in node-negative breast cancer

8 July 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24330518

12 December 2020

inferred from PubMed ID database lookup

WW domains in the heart of Smad regulation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24330518

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1186/1471-2407-13-593

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24330518%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

11 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24330518%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

24330518

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24330518%20AND%20SRC:MED&resulttype=core&format=json