Generation of functional insulin-producing cells from neonatal porcine liver-derived cells by PDX1/VP16, BETA2/NeuroD and MafA. (Q35048202)

6 August 2017

title

Generation of functional insulin-producing cells from neonatal porcine liver-derived cells by PDX1/VP16, BETA2/NeuroD and MafA. (English)

1 reference

6 August 2017

Dong-Sik Ham

1

1 reference

6 August 2017

Juyoung Shin

2

1 reference

6 August 2017

Ji-Won Kim

3

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6 August 2017

Heon-Seok Park

4

1 reference

6 August 2017

Jae-Hyoung Cho

5

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6 August 2017

Kun-Ho Yoon

6

1 reference

6 August 2017

language of work or name

English

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publication date

15 November 2013

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6 August 2017

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6 August 2017

volume

8

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6 August 2017

issue

11

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6 August 2017

page(s)

e79076

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Creative Commons Attribution 4.0 International

6 August 2017

copyright license

start time

15 November 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Adenoviruses Expressing PDX-1, BETA2/NeuroD and MafA Induces the Transdifferentiation of Porcine Neonatal Pancreas Cell Clusters and Adult Pig Pancreatic Cells into Beta-Cells

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Combination of MafA, PDX-1 and NeuroD is a useful tool to efficiently induce insulin-producing surrogate beta-cells

8 July 2018

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Neonatal pig liver-derived progenitors for insulin-producing cells: an in vitro study.

8 July 2018

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Pancreas and beta-cell development: from the actual to the possible

8 July 2018

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Liver stem cell-derived beta-cell surrogates for treatment of type 1 diabetes

8 July 2018

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Cell-replacement therapy for diabetes: Generating functional insulin-producing tissue from adult human liver cells.

8 July 2018

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PDX-1/VP16 fusion protein, together with NeuroD or Ngn3, markedly induces insulin gene transcription and ameliorates glucose tolerance

8 July 2018

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A crucial role of MafA as a novel therapeutic target for diabetes

8 July 2018

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In vivo and in vitro characterization of insulin-producing cells obtained from murine bone marrow

8 July 2018

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HGF-, EGF-, and dexamethasone-induced gene expression patterns during formation of tissue in hepatic organoid cultures

8 July 2018

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Liver chip and gene shaving.

8 July 2018

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Pancreatic duodenal homeobox-1, PDX-1, a major regulator of beta cell identity and function.

8 July 2018

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Hepatocyte differentiation: from the endoderm and beyond

8 July 2018

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8 July 2018

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Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen

8 July 2018

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Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia

8 July 2018

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Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3.

8 July 2018

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Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/NeuroD-deficient mice

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Intrahepatic islet transplantation in type 1 diabetic patients does not restore hypoglycemic hormonal counterregulation or symptom recognition after insulin independence

8 July 2018

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Neonatal porcine pancreatic cell clusters as a potential source for transplantation in humans: characterization of proliferation, apoptosis, xenoantigen expression and gene delivery with recombinant AAV.

21 January 2018

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Differentiation of human liver-derived, insulin-producing cells toward the beta-cell phenotype

21 January 2018

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In vitro transdifferentiation of adult pancreatic acinar cells into insulin-expressing cells

21 January 2018

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Metabolic impact of glucokinase overexpression in liver: lowering of blood glucose in fed rats is accompanied by hyperlipidemia

21 January 2018

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Conversion of immortal liver progenitor cells into pancreatic endocrine progenitor cells by persistent expression of Pdx-1.

21 January 2018

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NeuroD-betacellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0079076

Dexamethasone suppresses the expansion and transdifferentiation of transplanted porcine neonatal pancreas cell clusters (NPCCs) into beta-cells in normal nude mice

21 January 2018

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BETA2/NeuroD1 null mice: a new model for transcription factor-dependent photoreceptor degeneration.

21 January 2018

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Differentiation and expansion of beta cell mass in porcine neonatal pancreatic cell clusters transplanted into nude mice.

25 October 2018

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Role of Pax4 in Pdx1-VP16-mediated liver-to-endocrine pancreas transdifferentiation

25 October 2018

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12 December 2020

MafA regulates expression of genes important to islet beta-cell function

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12 December 2020

In Vitro Generation of Pancreatic Endocrine Cells from Human Adult Fibroblast-Like Limbal Stem Cells

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12 December 2020

NeuroD and reaggregation induce β-cell specific gene expression in cultured hepatocytes

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12 December 2020

Transplantation of insulin-producing cells derived from umbilical cord stromal mesenchymal stem cells to treat NOD mice

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0079076

Identifiers

DOI

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6 August 2017

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6 August 2017

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