Tauroursodeoxycholic acid reduces apoptosis and protects against neurological injury after acute hemorrhagic stroke in rats (Q35022852)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12721362%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

title

Tauroursodeoxycholic acid reduces apoptosis and protects against neurological injury after acute hemorrhagic stroke in rats (English)

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3 November 2019

1 reference

1

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3 November 2019

Susana Solá

2

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3 November 2019

Rui E. Castro

4

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3 November 2019

7

Clifford J Steer

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3 November 2019

author name string

Zhenhong Nan

3

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3 November 2019

Paulo S Ribeiro

5

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3 November 2019

Walter C Low

6

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3 November 2019

language of work or name

English

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publication date

29 April 2003

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12721362%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

3 November 2019

published in

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3 November 2019

volume

100

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3 November 2019

issue

10

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3 November 2019

page(s)

6087-6092

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Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation

3 November 2019

cites work

1 reference

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8 July 2018

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Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease.

8 July 2018

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Missing pieces in the NF-kappaB puzzle

8 July 2018

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Bilirubin induces apoptosis via the mitochondrial pathway in developing rat brain neurons.

8 July 2018

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Intracerebral hemorrhage-induced neuronal death

8 July 2018

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Amyloid beta-peptide disrupts mitochondrial membrane lipid and protein structure: protective role of tauroursodeoxycholate.

8 July 2018

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Multiple molecular penumbras after focal cerebral ischemia

8 July 2018

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Evidence for apoptosis after intercerebral hemorrhage in rat striatum

8 July 2018

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Cellular survival: a play in three Akts

8 July 2018

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Ursodeoxycholic acid prevents cytochrome c release in apoptosis by inhibiting mitochondrial membrane depolarization and channel formation

8 July 2018

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NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

8 July 2018

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Is NF-kappaB the sensor of oxidative stress?

8 July 2018

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A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation

8 July 2018

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Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic-ischemic brain injury

8 July 2018

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Surgery for primary intracerebral hemorrhage: is it safe and effective? A systematic review of case series and randomized trials

8 July 2018

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Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

8 July 2018

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The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

8 July 2018

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Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

8 July 2018

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Expression of interleukin-1 beta converting enzyme gene family and bcl-2 gene family in the rat brain following permanent occlusion of the middle cerebral artery

8 July 2018

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Apoptosis repressor genes Bcl-2 and Bcl-x-long are expressed in the rat brain following global ischemia

8 July 2018

1 reference

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Ischemia-induced neuronal apoptosis

8 July 2018

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The role of inflammation and cytokines in brain injury

8 July 2018

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Altered expression of Bcl-2, Bcl-X, Bax, and c-Fos colocalizes with DNA fragmentation and ischemic cell damage following middle cerebral artery occlusion in rats

8 July 2018

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An ICE inhibitor, z-VAD-DCB attenuates ischaemic brain damage in the rat.

8 July 2018

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Cytokine receptor signalling

8 July 2018

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Animal models of cerebral stroke: pharmacological protection of function

8 July 2018

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Collagenase-induced intracerebral hemorrhage in rats

8 July 2018

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Neuroprotection by a bile acid in an acute stroke model in the rat.

8 July 2018

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Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes

25 October 2018

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A bile acid protects against motor and cognitive deficits and reduces striatal degeneration in the 3-nitropropionic acid model of Huntington's disease.

25 October 2018

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Neuronal, but not microglial, accumulation of extravasated serum proteins after intracerebral hemolysate exposure is accompanied by cytochrome c release and DNA fragmentation

25 October 2018

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Antisense oligodeoxynucleotide inhibition of tumor necrosis factor-alpha expression is neuroprotective after intracerebral hemorrhage

25 October 2018

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Tauroursodeoxycholic acid partially prevents apoptosis induced by 3-nitropropionic acid: evidence for a mitochondrial pathway independent of the permeability transition

25 October 2018

1 reference

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Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family

25 October 2018

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Differential Regulation of Bax, Bcl‐2, and Bcl‐X Proteins in Focal Cortical Ischemia in the Rat

25 October 2018

1 reference

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Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats.

25 October 2018

1 reference

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Nuclear factor-kappaB and cell death after experimental intracerebral hemorrhage in rats

25 October 2018

1 reference

12 December 2020

Inhibition of caspase-1-like activity by Ac-Tyr-Val-Ala-Asp-chloromethyl ketone induces long-lasting neuroprotection in cerebral ischemia through apoptosis reduction and decrease of proinflammatory cytokines

1 reference

12 December 2020

Bile acid concentrations in human and rat liver tissue and in hepatocyte nuclei

1 reference

12 December 2020

Effect of tauroursodeoxycholic acid on bile-acid-induced apoptosis and cytolysis in rat hepatocytes

1 reference

12 December 2020

Mechanisms of ischemic brain damage with intracerebral hemorrhage.

1 reference

12 December 2020

Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain

1 reference

12 December 2020

Collagenase-induced intrastriatal hemorrhage in rats results in long-term locomotor deficits

1 reference

12 December 2020

Temporal profile of in situ DNA fragmentation after transient middle cerebral artery occlusion in the rat

1 reference

12 December 2020

Risk factors for impaired outcome after spontaneous intracerebral hemorrhage

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1031632100

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12721362%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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release_4m27t73dlnfkdlwebbqxzf5gty

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https://api.fatcat.wiki/v0/release/4m27t73dlnfkdlwebbqxzf5gty

24 November 2022

mapped directly with Wikidata item

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12721362%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

PubMed publication ID

12721362

1 reference