In vivo characteristics of cationic liposomes as delivery vectors for gene therapy (Q35012639)

5 August 2017

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title

In vivo characteristics of cationic liposomes as delivery vectors for gene therapy (English)

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5 August 2017

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Grietje Molema

4

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author name string

Sandrine A L Audouy

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1

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5 August 2017

Lou F M H de Leij

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2

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5 August 2017

Dick Hoekstra

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3

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5 August 2017

publication date

1 November 2002

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5 August 2017

published in

Pharmaceutical Research

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5 August 2017

volume

19

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5 August 2017

issue

11

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5 August 2017

page(s)

1599-1605

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Oxygen radical-mediated pulmonary toxicity induced by some cationic liposomes

5 August 2017

cites work

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12 December 2020

Biodistribution and gene expression of lipid/plasmid complexes after systemic administration

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12 December 2020

Studies of direct intratumoral gene transfer using cationic lipid-complexed plasmid DNA

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12 December 2020

Pulmonary surfactant inhibits cationic liposome-mediated gene delivery to respiratory epithelial cells in vitro

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12 December 2020

Cationic liposome-mediated gene delivery to the liver and to hepatocellular carcinomas in mice

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12 December 2020

Liposome-mediated, nonviral gene transfer induces a systemic inflammatory response which can exacerbate pre-existing inflammation

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12 December 2020

Evidence for safety and efficacy of DOTAP cationic liposome mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis

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12 December 2020

Comparison between intratracheal and intravenous administration of liposome-DNA complexes for cystic fibrosis lung gene therapy

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12 December 2020

Characterization of Cationic Liposome-Mediated Gene TransferIn Vivoby Intravenous Administration

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12 December 2020

A clinical inflammatory syndrome attributable to aerosolized lipid-DNA administration in cystic fibrosis

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12 December 2020

Promoter Attenuation in Gene Therapy: Interferon-γand Tumor Necrosis Factor-αInhibit Transgene Expression

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12 December 2020

Vaxfectin enhances the humoral immune response to plasmid DNA-encoded antigens

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12 December 2020

Pulmonary cytokine responses associated with PEI-DNA aerosol gene therapy

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12 December 2020

Basis of pulmonary toxicity associated with cationic lipid-mediated gene transfer to the mammalian lung

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12 December 2020

A concentrated and stable aerosol formulation of cationic lipid:DNA complexes giving high-level gene expression in mouse lung

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12 December 2020

Cationic lipid gene transfer of an IL-2 transgene leads to activation of natural killer cells in a SCID mouse human tumor xenograft

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12 December 2020

Inhibitory effects of tumor necrosis factor-alpha on cationic lipid-mediated gene delivery to airway cells in vitro

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12 December 2020

Contribution of plasmid DNA to hepatotoxicity after systemic administration of lipoplexes

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12 December 2020

Immunotherapy of advanced malignancy by direct gene transfer of an interleukin-2 DNA/DMRIE/DOPE lipid complex: phase I/II experience

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12 December 2020

Biodistribution of radiolabeled lipid-DNA complexes and DNA in mice

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12 December 2020

Cationic lipids are essential for gene delivery mediated by intravenous administration of lipoplexes

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12 December 2020

Catheter-mediated vascular endothelial growth factor gene transfer to human coronary arteries after angioplasty

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12 December 2020

Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy

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12 December 2020

Antitumor effect and cellular immunity activation by murine interferon-beta gene transfer against intracerebral glioma in mouse

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12 December 2020

Attenuating the growth of tumors by intratumoral administration of DNA encoding Pseudomonas exotoxin via cationic liposomes

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12 December 2020

Cancer Gene Therapy Using Plasmid DNA: Pharmacokinetic Study of DNA Following Injection in Mice

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12 December 2020

Tissue distribution of the cytofectin component of a plasmid-DNA/cationic lipid complex following intravenous administration in mice

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12 December 2020

Effect of immune response on gene transfer to the lung via systemic administration of cationic lipidic vectors

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12 December 2020

Improved DNA: liposome complexes for increased systemic delivery and gene expression

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12 December 2020

Gene expression and antitumor effects following direct interferon (IFN)-gamma gene transfer with naked plasmid DNA and DC-chol liposome complexes in mice

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12 December 2020

Enhanced gene delivery to human airway epithelial cells using an integrin-targeting lipoplex.

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12 December 2020

Proteoglycans mediate cationic liposome-DNA complex-based gene delivery in vitro and in vivo

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12 December 2020

In vivo cytokine gene therapy of human tumor xenografts in SCID mice by liposome-mediated DNA delivery

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12 December 2020

Cationic lipid-mediated transfection in vitro and in vivo (review).

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12 December 2020

Systemic Gene Expression After Intravenous DNA Delivery into Adult Mice

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12 December 2020

LPD lipopolyplex initiates a potent cytokine response and inhibits tumor growth

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12 December 2020

Comprehensive analysis of the acute toxicities induced by systemic administration of cationic lipid:plasmid DNA complexes in mice

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12 December 2020

Sequential injection of cationic liposome and plasmid DNA effectively transfects the lung with minimal inflammatory toxicity

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12 December 2020

Cationic lipids enhance cytokine and cell influx levels in the lung following administration of plasmid: cationic lipid complexes

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12 December 2020

Lipoplex-mediated gene delivery to the lung occurs within 60 minutes of intravenous administration

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12 December 2020

Plasmid DNA gene therapy: studies with the human interleukin-2 gene in tumor cells in vitro and in the murine B16 melanoma model in vivo.

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12 December 2020

Transfection of nasal mucosa with a normal alpha1-antitrypsin gene in alpha1-antitrypsin-deficient subjects: comparison with protein therapy

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12 December 2020

Cationic lipid-mediated CFTR gene transfer to the lungs and nose of patients with cystic fibrosis: a double-blind placebo-controlled trial.

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12 December 2020

Mechanism of lipoplex gene delivery in mouse lung: binding and internalization of fluorescent lipid and DNA components

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12 December 2020

Intravenous cytokine gene delivery by lipid-DNA complexes controls the growth of established lung metastases

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12 December 2020

The immunobiology and clinical potential of immunostimulatory CpG oligodeoxynucleotides

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12 December 2020

Organ-specific endothelial cell uptake of cationic liposome-DNA complexes in mice

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12 December 2020

Liposome-mediated DNA vaccination: the effect of vesicle composition

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12 December 2020

Systemic gene delivery expands the repertoire of effective antiangiogenic agents

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12 December 2020

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure

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12 December 2020

Lipid-DNA complexes induce potent activation of innate immune responses and antitumor activity when administered intravenously

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12 December 2020

Precision-cut organ slices as a tool to study toxicity and metabolism of xenobiotics with special reference to non-hepatic tissues

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12 December 2020

Intranasal immunization with plasmid DNA-lipid complexes elicits mucosal immunity in the female genital and rectal tracts

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12 December 2020

Factors influencing the efficiency of cationic liposome-mediated intravenous gene delivery

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12 December 2020

Intratumoral pharmacokinetics and in vivo gene expression of naked plasmid DNA and its cationic liposome complexes after direct gene transfer

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12 December 2020

Factors controlling the efficiency of cationic lipid-mediated transfection in vivo via intravenous administration

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12 December 2020

Activation of host antitumoral responses by cationic lipid/DNA complexes.

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12 December 2020

Identifiers

DOI

10.1023/A:1020989709019

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5 August 2017

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