Following cytochrome c release, autophagy is inhibited during chemotherapy-induced apoptosis by caspase 8-mediated cleavage of Beclin 1. (Q34987859)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21444671%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Following cytochrome c release, autophagy is inhibited during chemotherapy-induced apoptosis by caspase 8-mediated cleavage of Beclin 1 (English)

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26 January 2020

0 references

1 reference

1 reference

8

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26 January 2020

Lin Zhang

9

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26 January 2020

7

Donna B Stolz

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26 January 2020

3

Quanhong Sun

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26 January 2020

5

Xiao-Ming Yin

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26 January 2020

4

Wen-Xing Ding

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26 January 2020

author name string

Hua Li

1

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26 January 2020

Peng Wang

2

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26 January 2020

Robert W Sobol

6

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26 January 2020

language of work or name

English

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publication date

28 March 2011

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26 January 2020

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26 January 2020

volume

71

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26 January 2020

issue

10

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26 January 2020

page(s)

3625-3634

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Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria.

26 January 2020

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1 reference

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Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis

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Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1.

8 July 2018

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8 July 2018

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Biochemical isolation and characterization of the tubulovesicular LC3-positive autophagosomal compartment

8 July 2018

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The autophagy effector Beclin 1: a novel BH3-only protein

8 July 2018

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Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis.

8 July 2018

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PUMA is directly activated by NF-kappaB and contributes to TNF-alpha-induced apoptosis

8 July 2018

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Toxic effects and their management: daily clinical challenges in the treatment of colorectal cancer

8 July 2018

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FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells

8 July 2018

1 reference

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Caspases in apoptosis and beyond

8 July 2018

1 reference

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Autophagy in the Pathogenesis of Disease

8 July 2018

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Epitope tagging of endogenous proteins for genome-wide ChIP-chip studies

8 July 2018

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Self-eating and self-killing: crosstalk between autophagy and apoptosis

8 July 2018

1 reference

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Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability

8 July 2018

1 reference

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The nuclear function of p53 is required for PUMA-mediated apoptosis induced by DNA damage

8 July 2018

1 reference

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Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein

8 July 2018

1 reference

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The Bcl-2 apoptotic switch in cancer development and therapy

8 July 2018

1 reference

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SMAC/Diablo mediates the proapoptotic function of PUMA by regulating PUMA-induced mitochondrial events

8 July 2018

1 reference

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Different fates of mitochondria: alternative ways for degradation?

8 July 2018

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Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy

8 July 2018

1 reference

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The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function

8 July 2018

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Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

8 July 2018

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PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells

8 July 2018

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Autophagy in cell death: an innocent convict?

8 July 2018

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Pharmacological manipulation of cell death: clinical applications in sight?

8 July 2018

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Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

8 July 2018

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Specific ablation of the apoptotic functions of cytochrome C reveals a differential requirement for cytochrome C and Apaf-1 in apoptosis

8 July 2018

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Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8

8 July 2018

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Cell death: critical control points

8 July 2018

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Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

8 July 2018

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Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

8 July 2018

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The expanding role of mitochondria in apoptosis

8 July 2018

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Role of BAX in the apoptotic response to anticancer agents

8 July 2018

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FLIP-mediated autophagy regulation in cell death control

8 July 2018

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Apoptosis blocks Beclin 1-dependent autophagosome synthesis: an effect rescued by Bcl-xL.

26 October 2018

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Novel regimens of capecitabine alone and combined with irinotecan and bevacizumab in colorectal cancer xenografts.

26 October 2018

1 reference

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GAPDH and autophagy preserve survival after apoptotic cytochrome c release in the absence of caspase activation

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3096685

Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3096685

Caspase-mediated cleavage of ATG6/Beclin-1 links apoptosis to autophagy in HeLa cells

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21444671

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-10-4475

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21444671%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21444671%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

PubMed publication ID

21444671

1 reference