Proteasome inhibition promotes Parkin-Ubc13 interaction and lysine 63-linked ubiquitination (Q34984311)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24023840%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

Proteasome inhibition promotes Parkin-Ubc13 interaction and lysine 63-linked ubiquitination (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24023840%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

main subject

protein ubiquitination

1 reference

2

1 reference

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20 February 2020

author name string

Grace G Y Lim

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24023840%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Xiao-Hui Ng

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24023840%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Adeline Henry-Basil

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24023840%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Roy W X Sim

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24023840%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Jeanne M M Tan

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24023840%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Chou Chai

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24023840%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Kah-Leong Lim

8

1 reference

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20 February 2020

language of work or name

English

0 references

publication date

2 September 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24023840%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24023840%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

volume

8

1 reference

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20 February 2020

issue

9

1 reference

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20 February 2020

page(s)

e73235

1 reference

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Creative Commons Attribution 4.0 International

20 February 2020

copyright license

start time

2 September 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Structure of the human Parkin ligase domain in an autoinhibited state

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Structure of parkin reveals mechanisms for ubiquitin ligase activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Ataxin-3 regulates aggresome formation of copper-zinc superoxide dismutase (SOD1) by editing K63-linked polyubiquitin chains

8 July 2018

1 reference

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Autoregulation of Parkin activity through its ubiquitin-like domain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Parkin mediates apparent E2-independent monoubiquitination in vitro and contains an intrinsic activity that catalyzes polyubiquitination.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF-kappaB signaling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Immunoreactivity to Lys63-linked polyubiquitin is a feature of neurodegeneration

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Protein misfolding and aggregation in Parkinson's disease.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Noncanonical E2 variant-independent function of UBC13 in promoting checkpoint protein assembly

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Autophagy-mediated clearance of aggresomes is not a universal phenomenon

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Ubiquitin-proteasome system dysfunction in Parkinson's disease: current evidence and controversies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Parkin mediates neuroprotection through activation of IkappaB kinase/nuclear factor-kappaB signaling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Parkin-mediated lysine 63-linked polyubiquitination: a link to protein inclusions formation in Parkinson's and other conformational diseases?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Alterations in the solubility and intracellular localization of parkin by several familial Parkinson's disease-linked point mutations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

The ubiquitin-proteasome pathway in Parkinson's disease and other neurodegenerative diseases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Loss of locus coeruleus neurons and reduced startle in parkin null mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Ubiquitylation of synphilin-1 and alpha-synuclein by SIAH and its presence in cellular inclusions and Lewy bodies imply a role in Parkinson's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Siah-1 facilitates ubiquitination and degradation of synphilin-1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Dorfin Localizes to Lewy Bodies and Ubiquitylates Synphilin-1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Parkin facilitates the elimination of expanded polyglutamine proteins and leads to preservation of proteasome function.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Ubiquitin-mediated proteolysis: biological regulation via destruction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Alpha-synuclein and parkin contribute to the assembly of ubiquitin lysine 63-linked multiubiquitin chains

8 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0073235

Parkin: a multifaceted ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0073235

Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0073235

Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0073235

Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0073235

Emerging role for autophagy in the removal of aggresomes in Schwann cells.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3759450

Parkin: a multipurpose neuroprotective agent?

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24023840

12 December 2020

inferred from PubMed ID database lookup

Diverse effects of pathogenic mutations of Parkin that catalyze multiple monoubiquitylation in vitro

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24023840

12 December 2020

inferred from PubMed ID database lookup

Derivation of primary mouse embryonic fibroblast (PMEF) cultures

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24023840

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1371/JOURNAL.PONE.0073235

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2wkvz5grnfhmpgpdna4etu73pm

30 July 2022

release_2wkvz5grnfhmpgpdna4etu73pm

ADS bibcode

2013PLoSO...873235L

0 references

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2wkvz5grnfhmpgpdna4etu73pm

30 July 2022

https://api.fatcat.wiki/v0/release/2wkvz5grnfhmpgpdna4etu73pm

1 reference

30 July 2022

https://api.fatcat.wiki/v0/release/2wkvz5grnfhmpgpdna4etu73pm

PubMed publication ID

1 reference

30 July 2022