Splenectomy reduces infarct volume and neuroinflammation in male but not female mice in experimental stroke (Q34980295)

5 August 2017

title

Splenectomy reduces infarct volume and neuroinflammation in male but not female mice in experimental stroke (English)

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5 August 2017

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5

Halina Offner

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5 August 2017

Abby L Dotson

1

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5 August 2017

Jianming Wang

series ordinal

2

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5 August 2017

Julie Saugstad

series ordinal

3

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5 August 2017

Stephanie J Murphy

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4

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5 August 2017

language of work or name

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26 November 2014

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Journal of Neuroimmunology

5 August 2017

published in

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5 August 2017

volume

278

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5 August 2017

page(s)

289-298

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Phenotypic changes in immune cell subsets reflect increased infarct volume in male vs. female mice

5 August 2017

cites work

1 reference

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PD-L1 enhances CNS inflammation and infarct volume following experimental stroke in mice in opposition to PD-1.

8 July 2018

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8 July 2018

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Acute splenic irradiation reduces brain injury in the rat focal ischemic stroke model

8 July 2018

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8 July 2018

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Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature

8 July 2018

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A transient decrease in spleen size following stroke corresponds to splenocyte release into systemic circulation

8 July 2018

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Regulatory T cells accumulate and proliferate in the ischemic hemisphere for up to 30 days after MCAO.

8 July 2018

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Distinctive effects of T cell subsets in neuronal injury induced by cocultured splenocytes in vitro and by in vivo stroke in mice

8 July 2018

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Sex, stroke, and inflammation: the potential for estrogen-mediated immunoprotection in stroke

8 July 2018

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The spleen contributes to stroke induced neurodegeneration through interferon gamma signaling

8 July 2018

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CD4+FoxP3+ regulatory T-cells in cerebral ischemic stroke

8 July 2018

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8 July 2018

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Cell adhesion molecules and ischemic stroke

8 July 2018

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8 July 2018

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T- and B-cell-deficient mice with experimental stroke have reduced lesion size and inflammation

8 July 2018

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Stroke in the female: role of biological sex and estrogen

8 July 2018

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Sex differences in the clinical presentation, resource use, and 3-month outcome of acute stroke in Europe: data from a multicenter multinational hospital-based registry

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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26 October 2018

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Splenectomy protects experimental rats from cerebral damage after stroke due to anti-inflammatory effects

26 October 2018

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26 October 2018

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Regulatory T cells protect the brain after stroke

26 October 2018

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Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke.

26 October 2018

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Splenic atrophy in experimental stroke is accompanied by increased regulatory T cells and circulating macrophages

26 October 2018

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26 October 2018

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26 October 2018

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26 October 2018

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26 October 2018

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Con: Regulatory T cells are protective in ischemic stroke

26 October 2018

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12 December 2020

On the mechanism of post-splenectomy leukocytosis in mice

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12 December 2020

Leukaemia inhibitory factor is over-expressed by ischaemic brain tissue concomitant with reduced plasma expression following acute stroke

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12 December 2020

Experimental stroke induces massive, rapid activation of the peripheral immune system

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12 December 2020

10.1016/J.JNEUROIM.2014.11.020

Identifiers

DOI

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5 August 2017

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5 August 2017

1 reference