Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability (Q34979483)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25559257%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

title

Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability (English)

1 reference

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26 February 2020

8

1 reference

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26 February 2020

11

Jeffrey A Bluestone

1 reference

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26 February 2020

author name string

Alexandria Huynh

1

1 reference

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26 February 2020

Michel DuPage

2

1 reference

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26 February 2020

Bhavana Priyadharshini

3

1 reference

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26 February 2020

Peter T Sage

4

1 reference

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26 February 2020

Jason Quiros

5

1 reference

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26 February 2020

Christopher M Borges

6

1 reference

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26 February 2020

Natavudh Townamchai

7

1 reference

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26 February 2020

Jeffrey C Rathmell

9

1 reference

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26 February 2020

Arlene H Sharpe

10

1 reference

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26 February 2020

Laurence A Turka

12

1 reference

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26 February 2020

language of work or name

English

0 references

publication date

5 January 2015

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26 February 2020

1 reference

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26 February 2020

volume

16

1 reference

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26 February 2020

issue

2

1 reference

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26 February 2020

page(s)

188-196

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Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer

26 February 2020

cites work

1 reference

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Signals and pathways controlling regulatory T cells

8 July 2018

1 reference

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Characterization of two distinct lymphoproliferative diseases caused by ectopic expression of the Notch ligand DLL4 on T cells

8 July 2018

1 reference

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CCR7 provides localized access to IL-2 and defines homeostatically distinct regulatory T cell subsets

8 July 2018

1 reference

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Self-antigen-driven activation induces instability of regulatory T cells during an inflammatory autoimmune response

8 July 2018

1 reference

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Stability and function of regulatory T cells is maintained by a neuropilin-1-semaphorin-4a axis.

8 July 2018

1 reference

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mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function

8 July 2018

1 reference

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An obligate cell-intrinsic function for CD28 in Tregs

8 July 2018

1 reference

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Novel Foxo1-dependent transcriptional programs control T(reg) cell function

8 July 2018

1 reference

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Metabolic checkpoints in activated T cells

8 July 2018

1 reference

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Systemic elevation of PTEN induces a tumor-suppressive metabolic state

8 July 2018

1 reference

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Scaffold protein Disc large homolog 1 is required for T-cell receptor-induced activation of regulatory T-cell function

8 July 2018

1 reference

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Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1

8 July 2018

1 reference

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Cutting edge: PHLPP regulates the development, function, and molecular signaling pathways of regulatory T cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4297515

Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.

8 July 2018

1 reference

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Stability of the regulatory T cell lineage in vivo.

8 July 2018

1 reference

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Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

8 July 2018

1 reference

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The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment

8 July 2018

1 reference

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In vivo expansion of T reg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression

8 July 2018

1 reference

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Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity

8 July 2018

1 reference

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T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.

8 July 2018

1 reference

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AMPK phosphorylation of raptor mediates a metabolic checkpoint

8 July 2018

1 reference

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Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces

8 July 2018

1 reference

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The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells

8 July 2018

1 reference

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Differential impact of mammalian target of rapamycin inhibition on CD4+CD25+Foxp3+ regulatory T cells compared with conventional CD4+ T cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4297515

PTEN inhibits IL-2 receptor-mediated expansion of CD4+ CD25+ Tregs

8 July 2018

1 reference

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An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4297515

Distinct IL-2 receptor signaling pattern in CD4+CD25+ regulatory T cells

8 July 2018

1 reference

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

8 July 2018

1 reference

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Control of regulatory T cell development by the transcription factor Foxp3

8 July 2018

1 reference

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The CD28 signaling pathway regulates glucose metabolism

8 July 2018

1 reference

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Growth factors can influence cell growth and survival through effects on glucose metabolism

8 July 2018

1 reference

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Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

8 July 2018

1 reference

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PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

8 July 2018

1 reference

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Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis

8 July 2018

1 reference

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Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4297515

Distinct roles for PTEN in prevention of T cell lymphoma and autoimmunity in mice

26 October 2018

1 reference

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Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4297515

The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4297515

DNA methylation controls Foxp3 gene expression

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4297515

IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4297515

Natural recovery and protection from autoimmune encephalomyelitis: contribution of CD4+CD25+ regulatory cells within the central nervous system.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4297515

A noninvasive genetic/pharmacologic strategy for visualizing cell morphology and clonal relationships in the mouse.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4297515

Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4297515

T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

26 October 2018

1 reference

12 December 2020

Regulation of D-3 phosphoinositides during T cell activation via the T cell antigen receptor/CD3 complex and CD2 antigens

1 reference

12 December 2020

Impaired Fas response and autoimmunity in Pten+/- mice

1 reference

12 December 2020

Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression

1 reference

12 December 2020

Foxp3 Transcription-Factor-Dependent and -Independent Regulation of the Regulatory T Cell Transcriptional Signature

1 reference

12 December 2020

Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses.

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNI.3077

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NI.3077

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25559257%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25559257%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

PubMed publication ID

25559257

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25559257%20AND%20SRC:MED&resulttype=core&format=json