IFN-gamma receptor signaling mediates spinal microglia activation driving neuropathic pain (Q34976863)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19380717%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

IFN-gamma receptor signaling mediates spinal microglia activation driving neuropathic pain (English)

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26 January 2020

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2

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26 January 2020

author name string

Makoto Tsuda

1

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26 January 2020

Junko Kitano

3

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26 January 2020

Hiroshi Shimoyama

4

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26 January 2020

Hidetoshi Tozaki-Saitoh

5

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26 January 2020

Kazuhide Inoue

6

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26 January 2020

language of work or name

English

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publication date

20 April 2009

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Proceedings of the National Academy of Sciences of the United States of America

26 January 2020

published in

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26 January 2020

volume

106

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26 January 2020

issue

19

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26 January 2020

page(s)

8032-8037

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Do glial cells control pain?

26 January 2020

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Transformation of the output of spinal lamina I neurons after nerve injury and microglia stimulation underlying neuropathic pain

8 July 2018

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BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain

8 July 2018

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The function of microglia through purinergic receptors: neuropathic pain and cytokine release

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Role of the immune system in chronic pain.

8 July 2018

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The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathy

8 July 2018

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Pure albumin is a potent trigger of calcium signalling and proliferation in microglia but not macrophages or astrocytes.

8 July 2018

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Neuropathic pain and spinal microglia: a big problem from molecules in "small" glia

8 July 2018

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Src kinases: a hub for NMDA receptor regulation

8 July 2018

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P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury

8 July 2018

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8 July 2018

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Glial activation: a driving force for pathological pain

8 July 2018

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Neuronal plasticity: increasing the gain in pain

8 July 2018

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8 July 2018

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Characterization of cell proliferation in rat spinal cord following peripheral nerve injury and the relationship with neuropathic pain.

8 July 2018

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Activation of p38 mitogen-activated protein kinase in spinal hyperactive microglia contributes to pain hypersensitivity following peripheral nerve injury

21 January 2018

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Role of spinal microglia in rat models of peripheral nerve injury and inflammation

21 January 2018

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Complement induction in spinal cord microglia results in anaphylatoxin C5a-mediated pain hypersensitivity

21 January 2018

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21 January 2018

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Inhibition of Microglial Activation Attenuates the Development but Not Existing Hypersensitivity in a Rat Model of Neuropathy

21 January 2018

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P2Y12 receptors in spinal microglia are required for neuropathic pain after peripheral nerve injury.

21 January 2018

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P2Y12 receptor upregulation in activated microglia is a gateway of p38 signaling and neuropathic pain

21 January 2018

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A CD36-initiated signaling cascade mediates inflammatory effects of beta-amyloid.

21 January 2018

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Possible involvement of increase in spinal fibronectin following peripheral nerve injury in upregulation of microglial P2X4, a key molecule for mechanical allodynia

21 January 2018

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Fibronectin/integrin system is involved in P2X(4) receptor upregulation in the spinal cord and neuropathic pain after nerve injury.

21 January 2018

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Reduced potassium-chloride co-transporter expression in spinal cord dorsal horn neurons contributes to inflammatory pain hypersensitivity in rats

21 January 2018

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Increased responsiveness of rat dorsal horn neurons in vivo following prolonged intrathecal exposure to interferon-gamma

21 January 2018

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21 January 2018

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Interferon-gamma induces characteristics of central sensitization in spinal dorsal horn neurons in vitro

21 January 2018

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Involvement of interferon-gamma in microglial-mediated loss of dopaminergic neurons.

21 January 2018

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Transcriptional response of human microglial cells to interferon-gamma

21 January 2018

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p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain.

26 October 2018

1 reference

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ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model

26 October 2018

1 reference

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CD45 inhibits CD40L-induced microglial activation via negative regulation of the Src/p44/42 MAPK pathway

21 January 2018

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12 December 2020

Identification of elastase as a secretory protease from cultured rat microglia

1 reference

12 December 2020

Neuroglial activation repertoire in the injured brain: graded response, molecular mechanisms and cues to physiological function

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12 December 2020

Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice

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12 December 2020

Mechanical allodynia and spinal up-regulation of P2X4 receptor in experimental autoimmune neuritis rats

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12 December 2020

Interferon-gamma receptors in nociceptive pathways: role in neuropathic pain-related behaviour

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12 December 2020

Monocytes recruited into the alveolar air space of mice show a monocytic phenotype but upregulate CD14

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0810420106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19380717%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

0 references

1 reference

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26 January 2020

PubMed publication ID

19380717

1 reference