Amyloid beta-degrading cryptidases: insulin degrading enzyme, presequence peptidase, and neprilysin (Q34777829)

4 August 2017

1 reference

title

Amyloid beta-degrading cryptidases: insulin degrading enzyme, presequence peptidase, and neprilysin (English)

1 reference

4 August 2017

1 reference

E Malito

1

1 reference

4 August 2017

R E Hulse

series ordinal

2

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4 August 2017

W-J Tang

series ordinal

3

1 reference

4 August 2017

language of work or name

1 reference

1 August 2008

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Cellular and Molecular Life Sciences

4 August 2017

published in

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4 August 2017

volume

65

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4 August 2017

issue

16

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4 August 2017

page(s)

2574-2585

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Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease

4 August 2017

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Structural studies of a bifunctional inhibitor of neprilysin and DPP-IV

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Alternative translation initiation generates a novel isoform of insulin-degrading enzyme targeted to mitochondria

7 July 2018

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7 July 2018

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Proteins interacting with the 26S proteasome

7 July 2018

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Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein

7 July 2018

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7 July 2018

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7 July 2018

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Human and mouse proteases: a comparative genomic approach

7 July 2018

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Amyloid-beta peptide levels in brain are inversely correlated with insulysin activity levels in vivo

7 July 2018

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7 July 2018

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Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

7 July 2018

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7 July 2018

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Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme

7 July 2018

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The HtrA Family of Proteases

7 July 2018

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7 July 2018

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Crystal structures of mitochondrial processing peptidase reveal the mode for specific cleavage of import signal sequences

7 July 2018

1 reference

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Degradation of the Alzheimer's amyloid beta peptide by endothelin-converting enzyme

7 July 2018

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Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases

7 July 2018

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A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

7 July 2018

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Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme

7 July 2018

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Structure of human neutral endopeptidase (Neprilysin) complexed with phosphoramidon

7 July 2018

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Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition

7 July 2018

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Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

7 July 2018

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7 July 2018

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Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

7 July 2018

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7 July 2018

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Electrostatic steering and ionic tethering in enzyme–ligand binding: Insights from simulations

7 July 2018

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7 July 2018

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7 July 2018

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Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Human insulin-degrading enzyme shares structural and functional homologies with E. coli protease III

7 July 2018

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7 July 2018

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Atrial natriuretic peptide (ANP) is a high-affinity substrate for rat insulin-degrading enzyme

7 July 2018

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7 July 2018

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7 July 2018

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The inactivation of insulin by tissue extracts; the effect of fasting on the insulinase content of rat liver.

7 July 2018

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Regulation of steady-state beta-amyloid levels in the brain by neprilysin and endothelin-converting enzyme but not angiotensin-converting enzyme

26 October 2018

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26 October 2018

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26 October 2018

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26 October 2018

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26 October 2018

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26 October 2018

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26 October 2018

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26 October 2018

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26 October 2018

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26 October 2018

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26 October 2018

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26 October 2018

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Abeta 42-induced increase in neprilysin is associated with prevention of amyloid plaque formation in vivo

26 October 2018

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26 October 2018

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Differential effects of proteases involved in intracellular degradation of amyloid beta-protein between detergent-soluble and -insoluble pools in CHO-695 cells

26 October 2018

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26 October 2018

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26 October 2018

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A three-dimensional model of endothelin-converting enzyme (ECE) based on the X-ray structure of neutral endopeptidase 24.11 (NEP).

26 October 2018

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Metabolic regulation of brain Abeta by neprilysin

26 October 2018

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Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy

26 October 2018

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A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

26 October 2018

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Reduced neprilysin in high plaque areas of Alzheimer brain: a possible relationship to deficient degradation of beta-amyloid peptide

26 October 2018

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Proteolytic Degradation of Alzheimer's Disease Amyloid β‐Peptide by a Metalloproteinase from Microglia Cells

26 October 2018

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Enzyme target to latch on to

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Effect of 'Insulinase-Inhibitor' on Destruction of Insulin by Intact Mouse

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Identifiers

DOI

1 reference

4 August 2017

1 reference

4 August 2017

1 reference