Synaptic protein degradation underlies destabilization of retrieved fear memory (Q34747479)

4 August 2017

title

Synaptic protein degradation underlies destabilization of retrieved fear memory (English)

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4 August 2017

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10

Bong-Kiun Kaang

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4 August 2017

Sue-Hyun Lee

1

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4 August 2017

Jun-Hyeok Choi

2

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4 August 2017

Nuribalhae Lee

3

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4 August 2017

Hye-Ryeon Lee

4

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4 August 2017

Jae-Ick Kim

5

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4 August 2017

Nam-Kyung Yu

6

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4 August 2017

Sun-Lim Choi

7

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4 August 2017

Seung-Hee Lee

8

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4 August 2017

Hyoung Kim

9

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4 August 2017

language of work or name

English

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publication date

7 February 2008

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4 August 2017

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4 August 2017

volume

319

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4 August 2017

issue

5867

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4 August 2017

page(s)

1253-1256

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Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval

4 August 2017

cites work

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Memory reconsolidation and extinction have distinct temporal and biochemical signatures.

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Temporally graded requirement for protein synthesis following memory reactivation

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Memory reconsolidation: sensitivity of spatial memory to inhibition of protein synthesis in dorsal hippocampus during encoding and retrieval

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Reconsolidation: the advantage of being refocused

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NMDA receptors are critical for unleashing consolidated auditory fear memories

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Stability of retrieved memory: inverse correlation with trace dominance

21 January 2018

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Protein synthesis at synaptic sites on dendrites

21 January 2018

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Activity level controls postsynaptic composition and signaling via the ubiquitin-proteasome system

21 January 2018

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Regulatory subunits of cAMP-dependent protein kinases are degraded after conjugation to ubiquitin: a molecular mechanism underlying long-term synaptic plasticity

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PKA-activated ApAF-ApC/EBP heterodimer is a key downstream effector of ApCREB and is necessary and sufficient for the consolidation of long-term facilitation

21 January 2018

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Behavioral and neural analysis of extinction

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Hippocampal involvement in contextual modulation of fear extinction.

21 January 2018

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Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation.

21 January 2018

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Glutamate stimulates glutamate receptor interacting protein 1 degradation by ubiquitin-proteasome system to regulate surface expression of GluR2.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1126/SCIENCE.1150541

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4 August 2017

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