Melatonin prevents death of neuroblastoma cells exposed to the Alzheimer amyloid peptide. (Q34737994)

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1 November 2019

title

Melatonin prevents death of neuroblastoma cells exposed to the Alzheimer amyloid peptide (English)

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1 November 2019

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Spiros Efthimiopoulos

7

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15 May 2020

author name string

M A Pappolla

1

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15 May 2020

M Sos

2

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15 May 2020

R A Omar

3

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15 May 2020

R J Bick

4

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15 May 2020

D L Hickson-Bick

5

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R J Reiter

6

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N K Robakis

8

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language of work or name

English

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publication date

1 March 1997

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1 November 2019

published in

Journal of Neuroscience

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volume

17

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issue

5

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15 May 2020

page(s)

1683-1690

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Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

15 May 2020

cites work

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12 December 2020

Daily variation in the concentration of melatonin and 5-methoxytryptophol in the human pineal gland: effect of age and Alzheimer's disease

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Ca2+ channel blockers attenuate beta-amyloid peptide toxicity to cortical neurons in culture.

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beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

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Chrono-neuroendocrinological aspects of physiological aging and senile dementia.

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Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene

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beta-Amyloid peptide free radical fragments initiate synaptosomal lipoperoxidation in a sequence-specific fashion: implications to Alzheimer's disease

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Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs

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Calcium-Mediated Mechanisms in Chemically Induced Cell Death

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Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides

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12 December 2020

Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores

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12 December 2020

Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis

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12 December 2020

Apoptotic cell death induced by beta-amyloid 1-42 peptide is cell type dependent

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12 December 2020

Nuclear localization of melatonin in different mammalian tissues: immunocytochemical and radioimmunoassay evidence

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12 December 2020

Abnormal melatonin response to 5-methoxypsoralen in dementia

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12 December 2020

Localization of superoxide dismutases in Alzheimer's disease and Down's syndrome neocortex and hippocampus

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12 December 2020

Apoptosis suppression by bcl-2 is correlated with the regulation of nuclear and cytosolic Ca2+.

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12 December 2020

Human cortical neuronal (HCN) cell lines: a model for amyloid beta neurotoxicity

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12 December 2020

Evidence for intracellular cleavage of the Alzheimer's amyloid precursor in PC12 cells

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12 December 2020

Antioxidant enzymes and survival of normal and simian virus 40-transformed mouse embryo cells after hyperthermia

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12 December 2020

Direct evidence of oxidative injury produced by the Alzheimer's beta-amyloid peptide (1-40) in cultured hippocampal neurons

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12 December 2020

Immunohistochemical evidence of oxidative [corrected] stress in Alzheimer's disease

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12 December 2020

Activation of metabotropic glutamate receptors protects cultured neurons against apoptosis induced by beta-amyloid peptide

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12 December 2020

Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein.

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12 December 2020

Amyloid beta peptide induces necrosis rather than apoptosis

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12 December 2020

Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

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12 December 2020

Secreted forms of beta-amyloid precursor protein protect hippocampal neurons against amyloid beta-peptide-induced oxidative injury

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12 December 2020

Production of the Alzheimer amyloid beta protein by normal proteolytic processing

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12 December 2020

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

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12 December 2020

Age-dependent reduction in serum melatonin concentrations in healthy human subjects

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12 December 2020

A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease

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12 December 2020

Exact cleavage site of Alzheimer amyloid precursor in neuronal PC-12 cells

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12 December 2020

beta-Amyloid precursor protein metabolites and loss of neuronal Ca2+ homeostasis in Alzheimer's disease.

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12 December 2020

Effects of melatonin on microtubule assembly depend on hormone concentration: Role of melatonin as a calmodulin antagonist

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12 December 2020

Cell death induced by β-amyloid 1–40 in MES 23.5 hybrid clone: the role of nitric oxide and NMDA-gated channel activation leading to apoptosis

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12 December 2020

Morning bright light therapy for sleep and behavior disorders in elderly patients with dementia

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12 December 2020

Hydrogen peroxide mediates amyloid beta protein toxicity

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12 December 2020

Calcium and neuronal injury in Alzheimer's disease. Contributions of beta-amyloid precursor protein mismetabolism, free radicals, and metabolic compromise

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12 December 2020

beta-Amyloid neurotoxicity in human cortical culture is not mediated by excitotoxins

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12 December 2020

Oxygen free radicals as inducers of heat shock protein synthesis in cultured human neuroblastoma cells: relevance to neurodegenerative disease

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12 December 2020

Familial Alzheimer's disease. A pedigree with a mis-sense mutation in the amyloid precursor protein gene (amyloid precursor protein 717 valine-->glycine).

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12 December 2020

A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

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12 December 2020

The pineal control of aging. The effects of melatonin and pineal grafting on the survival of older mice

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12 December 2020

The pineal gland: a circadian or seasonal aging clock?

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12 December 2020

Heme oxygenase-1 is associated with the neurofibrillary pathology of Alzheimer's disease.

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12 December 2020

Amyloid beta-peptide is produced by cultured cells during normal metabolism

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12 December 2020

The pineal gland and melatonin in relation to aging: a summary of the theories and of the data

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12 December 2020

Flow cytometric analysis of cell cycle-dependent changes in cell thiol level by combining a new laser dye with Hoechst 33342.

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12 December 2020

Calmodulin mediates melatonin cytoskeletal effects.

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12 December 2020

Interfering with apoptosis: Ca(2+)-binding protein ALG-2 and Alzheimer's disease gene ALG-3

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12 December 2020

Amyloid beta-peptide impairs ion-motive ATPase activities: evidence for a role in loss of neuronal Ca2+ homeostasis and cell death

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12 December 2020

Chronic inhibition of superoxide dismutase produces apoptotic death of spinal neurons

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12 December 2020

Ion transport ATPases as targets for free radical damage. Protection by an aminosteroid of the Ca2+ pump ATPase and Na+/K+ pump ATPase of human red blood cell membranes

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12 December 2020

Vitamin E protects nerve cells from amyloid beta protein toxicity

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12 December 2020

The heat shock/oxidative stress connection. Relevance to Alzheimer disease.

1 reference

12 December 2020

Methodological variables in the assessment of beta amyloid neurotoxicity

1 reference

12 December 2020

10.1523/JNEUROSCI.17-05-01683.1997

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573387&resulttype=core&format=json

15 May 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6573387&resulttype=core&format=json

15 May 2020

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