Parkin ubiquitinates Drp1 for proteasome-dependent degradation: implication of dysregulated mitochondrial dynamics in Parkinson disease (Q34719767)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21292769%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

Parkin ubiquitinates Drp1 for proteasome-dependent degradation: implication of dysregulated mitochondrial dynamics in Parkinson disease (English)

1 reference

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21 January 2020

main subject

protein ubiquitination

1 reference

1 reference

11

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21 January 2020

Quan Chen

12

1 reference

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21 January 2020

6

Min Liu

1 reference

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21 January 2020

author name string

Hongxia Wang

1

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21 January 2020

Pingping Song

2

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21 January 2020

Lei Du

3

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21 January 2020

Weili Tian

4

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21 January 2020

Wen Yue

5

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21 January 2020

Dengwen Li

7

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21 January 2020

Bin Wang

8

1 reference

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21 January 2020

Yushan Zhu

9

1 reference

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21 January 2020

Cheng Cao

10

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21 January 2020

language of work or name

English

0 references

publication date

3 February 2011

1 reference

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Journal of Biological Chemistry

21 January 2020

published in

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21 January 2020

volume

286

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issue

13

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21 January 2020

page(s)

11649-11658

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describes a project that uses

21 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3064217/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation

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Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission

7 July 2018

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Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation

7 July 2018

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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

7 July 2018

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7 July 2018

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Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery

7 July 2018

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Unraveling the role of defective genes in Parkinson's disease

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1

7 July 2018

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7 July 2018

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7 July 2018

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Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants

7 July 2018

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Neuronal degeneration and mitochondrial dysfunction

7 July 2018

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The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis

7 July 2018

1 reference

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Parkin and the molecular pathways of Parkinson's disease

7 July 2018

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Mitochondria and degenerative disorders

7 July 2018

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Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

7 July 2018

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Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

7 July 2018

1 reference

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The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064217

Intra- and intermolecular domain interactions of the C-terminal GTPase effector domain of the multimeric dynamin-like GTPase Drp1.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064217

26 October 2018

Dynamic mitochondria.

1 reference

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26 October 2018

1 reference

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Clinical analysis of 17 patients in 12 Japanese families with autosomal-recessive type juvenile parkinsonism.

9 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21292769

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Fzo1, a protein involved in mitochondrial fusion, inhibits apoptosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21292769

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M110.144238

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21292769%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21292769%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

PubMed publication ID

21292769

1 reference