Gene therapy for hemophilia A: production of therapeutic levels of human factor VIII in vivo in mice (Q34675871)

3 August 2017

title

Gene therapy for hemophilia A: production of therapeutic levels of human factor VIII in vivo in mice (English)

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3 August 2017

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Coagulation factor VIII

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hemophilia A

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author name string

Dwarki VJ

1

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3 August 2017

Belloni P

2

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3 August 2017

Nijjar T

3

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3 August 2017

Smith J

4

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3 August 2017

Couto L

5

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3 August 2017

Rabier M

6

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3 August 2017

Clift S

7

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3 August 2017

Berns A

8

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3 August 2017

Cohen LK

9

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3 August 2017

language of work or name

English

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publication date

1 February 1995

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Proceedings of the National Academy of Sciences of the United States of America

3 August 2017

published in

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3 August 2017

volume

92

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3 August 2017

issue

4

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3 August 2017

page(s)

1023-1027

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Recombinant factor VIII for the treatment of previously untreated patients with hemophilia A. Safety, efficacy, and development of inhibitors. Kogenate Previously Untreated Patient Study Group

3 August 2017

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In vivo production of human factor VII in mice after intrasplenic implantation of primary fibroblasts transfected by receptor-mediated, adenovirus-augmented gene delivery

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Assay of factor VIII:C with a chromogenic substrate

7 July 2018

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Purified human factor VIII procoagulant protein: comparative hemostatic response after infusions into hemophilic and von Willebrand disease dogs

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Characterization of the polypeptide composition of human factor VIII:C and the nucleotide sequence and expression of the human kidney cDNA.

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Hemophilia, beaten on one front, is beset on others

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7 July 2018

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Two independent domains of factor VIII co-expressed using recombinant vaccinia viruses have procoagulant activity

7 July 2018

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Proteolytic processing of human factor VIII. Correlation of specific cleavages by thrombin, factor Xa, and activated protein C with activation and inactivation of factor VIII coagulant activity

7 July 2018

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Construction and characterization of an active factor VIII variant lacking the central one-third of the molecule

7 July 2018

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7 July 2018

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A large region (approximately equal to 95 kDa) of human factor VIII is dispensable for in vitro procoagulant activity

7 July 2018

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7 July 2018

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Factor concentrates for treatment of hemophilia: which one to choose?

7 July 2018

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Use of recombinant antihemophilic factor in the treatment of two patients with classic hemophilia

7 July 2018

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7 July 2018

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7 July 2018

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Expression of functional factor VIII in primary human skin fibroblasts after retrovirus-mediated gene transfer.

7 July 2018

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Retroviral-mediated transfer and amplification of a functional human factor VIII gene

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Toward gene therapy for hemophilia A: long-term persistence of factor VIII-secreting fibroblasts after transplantation into immunodeficient mice.

26 October 2018

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26 October 2018

Lessons from hemophilia

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Twenty-five years' experience of prophylactic treatment in severe haemophilia A and B.

26 October 2018

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A2 domain of human recombinant-derived factor VIII is required for procoagulant activity but not for thrombin cleavage

26 October 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/7862626

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Toward gene therapy in haemophilia A: retrovirus-mediated transfer of a factor VIII gene into murine haematopoietic progenitor cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7862626

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.92.4.1023

1 reference

3 August 2017

0 references

1 reference

3 August 2017

1 reference