Promoter mutations that increase amyloid precursor-protein expression are associated with Alzheimer disease (Q34658251)

3 August 2017

title

Promoter mutations that increase amyloid precursor-protein expression are associated with Alzheimer disease (English)

1 reference

3 August 2017

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Cornelia M. van Duijn

8

Christine Van Broeckhoven

Cornelia M van Duijn

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10

Christine Van Broeckhoven

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Kristel Sleegers

4

Kristel Sleegers

1 reference

3 August 2017

1

Jessie Theuns

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3 August 2017

Sebastiaan Engelborghs

3

Sebastiaan Engelborghs

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3 August 2017

Nathalie Brouwers

2

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Peter Paul De Deyn

9

Peter P De Deyn

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3 August 2017

7

Tim De Pooter

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3 August 2017

5

Veerle Bogaerts

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3 August 2017

6

Ellen Corsmit

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3 August 2017

language of work or name

English

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publication date

10 April 2006

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American Journal of Human Genetics

3 August 2017

published in

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3 August 2017

volume

78

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3 August 2017

issue

6

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3 August 2017

page(s)

936-946

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APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy

3 August 2017

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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No evidence that common allelic variation in the Amyloid Precursor Protein (APP) gene confers susceptibility to Alzheimer's disease

7 July 2018

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Identification and characterization of a kappa B/Rel binding site in the regulatory region of the amyloid precursor protein gene.

7 July 2018

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Promoter activity of the gene encoding the beta-amyloid precursor protein is up-regulated by growth factors, phorbol ester, retinoic acid and interleukin-1.

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesis

7 July 2018

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7 July 2018

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The expression of the amyloid precursor protein (APP) is regulated by two GC-elements in the promoter

7 July 2018

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Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs

7 July 2018

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Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

7 July 2018

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Positive and negative regulatory elements for the expression of the Alzheimer's disease amyloid precursor-encoding gene in mouse

7 July 2018

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Screening for mutations in the open reading frame and promoter of the beta-amyloid precursor protein gene in familial Alzheimer's disease: identification of a further family with APP717 Val-->Ile

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474091

Dose dependent effect of APOE epsilon4 on behavioral symptoms in frontal lobe dementia

7 July 2018

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The UBQLN1 polymorphism, UBQ-8i, at 9q22 is not associated with Alzheimer's disease with onset before 70 years.

26 October 2018

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alpha-Synuclein promoter confers susceptibility to Parkinson's disease.

26 October 2018

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Alzheimer-associated C allele of the promoter polymorphism -22C>T causes a critical neuron-specific decrease of presenilin 1 expression.

26 October 2018

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PRNP Val129 homozygosity increases risk for early-onset Alzheimer's disease.

26 October 2018

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Neuronal injury affects expression of helix-loop-helix transcription factors

26 October 2018

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Polymorphisms in the promoter of the human APP gene: functional evaluation and allele frequencies in Alzheimer disease

26 October 2018

1 reference

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Genetic variability at the amyloid-beta precursor protein locus may contribute to the risk of late-onset Alzheimer's disease.

26 October 2018

1 reference

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A full genome scan for late onset Alzheimer's disease.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474091

Increased levels of the Kunitz protease inhibitor-containing beta APP mRNAs in rat brain following neurotoxic damage.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474091

Analysis of the c-FOS gene on chromosome 14 and the promoter of the amyloid precursor protein gene in familial Alzheimer's disease.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474091

Structural features of the 5' upstream regulatory region of the gene encoding rat amyloid precursor protein

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474091

Full genome screen for Alzheimer disease: Stage II analysis

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1474091

Expression of beta-amyloid precursor protein in reactive astrocytes following neuronal damage

26 October 2018

1 reference

12 December 2020

Beta-amyloid precursor protein (beta APP) as a marker for axonal injury after head injury

1 reference

12 December 2020

The initiator element and proximal upstream sequences affect transcriptional activity and start site selection in the amyloid beta-protein precursor promoter

1 reference

12 December 2020

Estimation of the Genetic Contribution of Presenilin-1 and -2 Mutations in a Population-Based Study of Presenile Alzheimer Disease

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Functional identification of the promoter of the gene encoding the Rhesus monkey β-amyloid precursor protein

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Increased susceptibility to sporadic Parkinson's disease by a certain combined alpha-synuclein/apolipoprotein E genotype

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12 December 2020

Identifiers

DOI

10.1086/504044

1 reference

3 August 2017

1 reference

3 August 2017

1 reference